Derek Jeter has put up the most career runs in the postseason, with 111 runs.

Interpreted as:

most postseason runs by a player in a career

	NAME	R	G	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Derek Jeter D. Jeter	111	158	650	200	32	5	20	61	66	5	135	18	5	734	302	57	9	4	3	14	.308	.374	.465	.838
2	Jose Altuve J. Altuve	89	105	436	118	21	0	27	56	43	2	75	9	5	484	220	48	0	3	2	15	.271	.337	.505	.841
3	Bernie Williams B. Williams	83	121	465	128	29	0	22	80	71	3	85	8	5	545	223	51	0	6	11	17	.275	.371	.480	.850
4	Manny Ramirez M. Ramirez	67	111	410	117	19	0	29	78	72	5	91	1	1	493	223	48	0	6	12	17	.285	.394	.544	.937
5	Kenny Lofton K. Lofton	65	95	392	97	12	4	7	34	38	2	68	34	6	438	138	23	3	3	3	4	.247	.315	.352	.667
6	Alex Bregman A. Bregman	63	102	380	91	18	1	19	55	56	9	66	3	1	447	168	38	0	2	4	11	.239	.349	.442	.791
7	Mookie Betts M. Betts	58	91	363	92	26	1	8	42	50	2	63	16	1	420	144	35	0	5	8	6	.253	.343	.397	.740
8	Chipper Jones C. Jones	58	93	338	97	18	0	13	47	72	1	61	8	3	417	154	31	1	5	11	10	.287	.409	.456	.864
9	George Springer G. Springer	57	83	343	93	21	0	23	48	36	4	91	4	2	384	183	44	0	1	1	5	.271	.346	.534	.880
10	Albert Pujols A. Pujols	57	88	304	97	18	1	19	54	50	5	46	1	2	360	174	38	0	1	20	7	.319	.422	.572	.995
11	Corey Seager C. Seager	55	78	299	76	17	1	19	48	42	3	79	3	0	346	152	37	0	2	3	6	.254	.350	.508	.858
12	David Justice D. Justice	55	112	398	89	17	2	14	63	64	5	79	3	2	471	152	33	0	4	7	7	.224	.335	.382	.717
13	Jorge Posada J. Posada	53	125	416	103	23	1	11	42	70	3	109	3	3	492	161	35	0	3	9	15	.248	.358	.387	.745
14	David Ortiz D. Ortiz	51	85	304	88	22	2	17	61	59	2	72	0	1	369	165	41	0	4	11	4	.289	.404	.543	.947
15	Rickey Henderson R. Henderson	47	60	222	63	12	4	5	20	37	2	32	33	6	262	98	21	0	1	0	1	.284	.389	.441	.831
16	Max Muncy M. Muncy	46	79	259	56	9	0	16	37	65	4	93	4	0	328	113	25	0	0	3	4	.216	.381	.436	.817
17	Enrique Hernández E. Hernández	46	103	294	80	11	2	16	42	27	4	75	3	3	328	143	29	1	2	2	3	.272	.339	.486	.826
18	Carlos Beltran C. Beltran	45	65	215	66	15	1	16	42	37	2	33	11	0	256	131	32	1	1	2	3	.307	.412	.609	1.021
19	Kyle Schwarber K. Schwarber	44	73	244	57	7	0	23	37	46	4	79	5	0	296	133	30	0	2	5	4	.234	.361	.545	.907
20	Tino Martinez T. Martinez	44	99	356	83	15	0	9	38	41	6	72	3	2	405	125	24	0	2	7	1	.233	.321	.351	.672
21	Justin Turner J. Turner	43	87	317	86	19	1	13	42	38	13	59	5	0	370	146	33	0	2	1	6	.271	.370	.461	.831
22	Andruw Jones A. Jones	43	76	238	65	8	0	10	34	34	2	50	5	5	279	103	18	1	4	2	5	.273	.363	.433	.796
23	Alex Rodriguez A. Rodriguez	43	76	278	72	16	0	13	41	39	9	77	8	3	330	127	29	1	3	4	6	.259	.365	.457	.822
24	Aaron Judge A. Judge	42	65	246	58	8	0	17	41	40	3	91	5	1	292	117	25	0	3	3	4	.236	.346	.476	.822
25	Bryce Harper B. Harper	42	57	208	57	14	1	17	34	38	2	56	8	1	250	124	32	1	1	4	5	.274	.390	.596	.986