Since 2016, Mookie Betts put up the most runs, with 1,040 runs.

Interpreted as:

most runs by a player scored 2016 to 2025

	NAME	R	G	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	wRC	WRAA	wOBA	wRC+	BRAA
1	Mookie Betts M. Betts	1,040	1,334	5,297	1,538	340	32	268	818	669	48	811	168	32	6,069	2,746	640	0	55	34	82	.290	.372	.518	.890	1033	306.1	.377	139	285.4
2	Freddie Freeman F. Freeman	974	1,428	5,405	1,660	384	25	263	898	741	78	1,120	91	23	6,266	2,883	672	0	42	117	112	.307	.396	.533	.929	1138	388.6	.391	147	365.7
3	Francisco Lindor F. Lindor	961	1,436	5,696	1,542	317	22	267	805	561	79	1,051	204	49	6,410	2,704	606	18	56	36	97	.271	.341	.475	.816	935	167.9	.348	121	162.4
4	José Ramírez J. Ramírez	919	1,429	5,406	1,533	374	37	277	905	619	43	726	267	56	6,122	2,812	688	1	53	110	79	.284	.359	.520	.879	992	260.6	.367	135	256.5
5	Jose Altuve J. Altuve	895	1,308	5,160	1,558	293	18	219	663	509	56	831	156	47	5,764	2,544	530	10	29	30	141	.302	.369	.493	.862	940	251.3	.368	138	263.2
6	Paul Goldschmidt P. Goldschmidt	889	1,453	5,363	1,518	312	16	256	820	725	42	1,390	107	18	6,162	2,630	584	0	32	59	110	.283	.371	.490	.861	999	261	.367	132	240.4
7	George Springer G. Springer	878	1,265	4,872	1,305	222	20	257	704	587	68	1,092	99	35	5,556	2,338	499	0	29	10	113	.268	.353	.480	.833	855	190.5	.357	130	200.9
8	Aaron Judge A. Judge	873	1,145	4,105	1,205	203	7	368	830	817	40	1,369	65	21	4,995	2,526	578	0	33	104	116	.294	.413	.615	1.028	1050	453.4	.425	178	457.2
9	Marcus Semien M. Semien	866	1,389	5,509	1,398	286	27	230	721	567	25	1,081	123	33	6,145	2,428	543	4	40	7	79	.254	.324	.441	.765	805	69.9	.329	110	75.1
10	Trea Turner T. Turner	865	1,239	5,117	1,523	281	48	185	640	379	41	1,016	313	51	5,560	2,455	514	2	21	11	87	.298	.350	.480	.829	847	181.6	.355	123	159.2
11	Christian Yelich C. Yelich	842	1,284	4,810	1,364	255	26	213	737	686	45	1,244	174	30	5,567	2,310	494	2	24	54	97	.284	.376	.480	.857	900	233.6	.366	132	218.8
12	Manny Machado M. Machado	830	1,443	5,606	1,558	293	11	301	929	535	21	1,103	83	26	6,216	2,776	605	0	54	68	173	.278	.340	.495	.835	929	185.2	.352	125	190.1
13	Bryce Harper B. Harper	826	1,275	4,605	1,273	303	9	266	803	826	39	1,205	115	36	5,522	2,392	578	4	48	114	106	.276	.387	.519	.907	958	296.1	.381	139	268.1
14	Xander Bogaerts X. Bogaerts	797	1,348	5,154	1,486	319	14	177	706	517	47	1,018	113	19	5,771	2,364	510	1	52	21	132	.288	.355	.459	.814	851	159.6	.349	119	134.5
15	Nolan Arenado N. Arenado	788	1,386	5,273	1,490	299	24	283	941	495	34	854	25	17	5,866	2,686	606	2	62	65	156	.283	.344	.509	.854	908	205.9	.358	119	139
16	Juan Soto J. Soto	775	1,096	3,857	1,086	199	16	244	697	896	19	833	95	27	4,801	2,049	459	3	26	80	101	.282	.417	.531	.948	919	344.3	.402	158	338.1
17	Charlie Blackmon C. Blackmon	762	1,162	4,501	1,325	250	54	182	632	394	78	860	64	33	5,014	2,229	486	11	30	27	59	.294	.359	.495	.854	798	196.4	.363	114	87.2
18	Alex Bregman A. Bregman	758	1,225	4,590	1,250	293	18	209	725	627	67	716	43	15	5,327	2,206	520	1	42	17	120	.272	.365	.481	.846	845	207.3	.362	133	214.7
19	Eugenio Suárez E. Suárez	756	1,448	5,204	1,271	234	12	308	878	593	95	1,653	29	17	5,952	2,453	554	0	60	15	120	.244	.329	.471	.801	841	127.8	.342	114	104.2
20	Kyle Schwarber K. Schwarber	748	1,222	4,312	993	169	13	324	741	728	46	1,450	34	16	5,111	2,160	506	1	24	46	49	.230	.346	.501	.847	795	182.7	.359	127	164.5
21	Nick Castellanos N. Castellanos	734	1,375	5,312	1,459	335	33	224	781	357	50	1,324	40	17	5,758	2,532	592	0	39	15	116	.275	.324	.477	.801	806	116.2	.340	113	93.5
22	Mike Trout M. Trout	719	996	3,518	1,010	182	23	265	621	706	69	1,015	101	17	4,323	2,033	470	0	30	96	41	.287	.413	.578	.991	861	342.9	.412	165	339.3
23	Rafael Devers R. Devers	715	1,143	4,409	1,215	288	12	235	747	470	40	1,086	33	19	4,944	2,232	535	1	24	68	101	.276	.349	.506	.855	776	183.1	.360	126	154.6
24	Carlos Santana C. Santana	713	1,400	4,974	1,184	236	10	218	715	791	27	921	35	4	5,827	2,094	464	0	35	34	109	.238	.344	.421	.765	777	78.2	.332	109	62
25	Matt Olson M. Olson	712	1,223	4,496	1,155	250	7	288	808	613	56	1,238	9	2	5,197	2,283	545	0	32	46	105	.257	.351	.508	.859	830	208.7	.363	133	209.2