The Boston Red Sox had their most strikeouts in a game on September 20, on June 5, 2001 and on June 14, 1974, with 20 strikeouts.

Interpreted as:

most so in a regular-season game for red sox

	TEAM	SO	DATE	TM		OPP	RESULT	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Red Sox	20	9/20/2024	BOS	vs	MIN	L 2-4	43	2	9	2	0	0	2	7	1	3	0	52	11	2	1	0	3	1	.209	.333	.256	.589
2	Red Sox	20	6/5/2001	BOS	vs	DET	W 4-3	62	4	12	0	0	4	4	6	3	2	0	72	24	4	1	0	4	0	.194	.296	.387	.683
3	Red Sox	20	6/14/1974	BOS	@	CAL	L 3-4	54	3	8	0	0	1	3	10	0	0	0	64	11	1	0	0	0	0	.148	.281	.204	.485
4	Red Sox	19	9/13/2015	BOS	@	TBR	W 2-0	49	2	14	1	0	0	2	2	0	3	2	51	15	1	0	0	0	2	.286	.314	.306	.620
5	Red Sox	19	8/12/1974	BOS	@	CAL	L 2-4	34	2	7	0	1	0	2	2	0	1	1	36	9	1	0	0	0	0	.206	.250	.265	.515
6	Red Sox	18	8/9/2014	BOS	@	LAA	L 4-5	60	4	6	1	0	0	3	4	0	2	0	66	7	1	0	2	0	1	.100	.152	.117	.268
7	Red Sox	18	5/6/2012	BOS	vs	BAL	L 6-9	63	6	16	4	0	1	6	4	0	0	2	68	23	5	0	1	0	2	.254	.294	.365	.659
8	Red Sox	18	10/2/2010	BOS	vs	NYY	L 5-6	39	5	11	2	0	0	3	8	0	1	0	47	13	2	0	0	0	1	.282	.404	.333	.738
9	Red Sox	18	7/9/2006	BOS	@	CWS	L 5-6	65	5	11	4	0	1	5	11	2	3	0	79	18	5	1	0	2	2	.169	.308	.277	.585
10	Red Sox	18	6/15/1965	BOS	@	DET	L 5-6	38	5	10	1	0	0	5	2	0	1	0	40	11	1	0	0	0	0	.263	.300	.289	.589
11	Americans	18	9/1/1906	BSA	vs	PHA	L 1-4	80	1	15	2	1	0	1	6	1	1		89	19	3	2				.188	.253	.238	.490
12	Red Sox	17	9/6/2023	BOS	@	TBR	L 1-3	32	1	5	2	1	0	1	1	0	1	0	33	9	3	0	0	0	0	.156	.182	.281	.463
13	Red Sox	17	6/23/2023	BOS	@	CWS	W 3-1	32	3	4	0	0	1	2	1	1	2	0	34	7	1	0	0	0	0	.125	.176	.219	.395
14	Red Sox	17	5/21/2021	BOS	@	PHI	W 11-3	41	11	13	4	0	2	10	2	0	1	0	43	23	6	0	0	1	0	.317	.349	.561	.910
15	Red Sox	17	6/18/2019	BOS	@	MIN	L 3-4	64	3	17	2	0	2	3	2	1	2	1	68	25	4	1	0	1	2	.266	.299	.391	.689
16	Red Sox	17	8/5/2018	BOS	vs	NYY	W 5-4	40	5	10	1	0	1	4	6	1	0	1	47	14	2	0	0	1	0	.250	.362	.350	.712
17	Red Sox	17	6/10/2013	BOS	@	TBR	W 10-8	54	10	15	3	0	0	10	8	0	3	0	62	18	3	0	0	1	3	.278	.371	.333	.704
18	Red Sox	17	6/4/2011	BOS	vs	OAK	W 9-8	57	9	18	7	0	1	9	5	0	3	1	62	28	8	0	0	3	1	.316	.371	.491	.862
19	Red Sox	17	9/21/2007	BOS	@	TBD	W 8-1	35	8	9	1	1	3	6	6	3	1	0	45	21	5	1	0	0	0	.257	.409	.600	1.009
20	Red Sox	17	9/18/1968	BOS	vs	BAL	W 4-0	27	4	5	0	0	0	4	5	0	0	0	34	5	0	1	1	0	0	.185	.303	.185	.488
21	Red Sox	17	5/6/1966	BOS	@	MIN	L 4-5	32	4	6	0	0	3	4	4	0	0	1	36	15	3	0	0	0	0	.188	.278	.469	.747
22	Red Sox	17	4/15/1966	BOS	@	CLE	L 7-8	41	7	7	2	1	0	7	10	1	0	0	54	11	3	2	0	3	0	.171	.346	.268	.614
23	Red Sox	17	7/4/1963	BOS	@	CLE	L 3-4	52	3	12	1	0	0	1	4	0	1	0	56	13	1	0	0	1	2	.231	.286	.250	.536
24	Red Sox	17	5/10/1961	BOS	@	LAA	W 3-2	34	3	6	0	0	1	3	1	0	0	0	35	9	1	0	0	0	0	.176	.200	.265	.465
25	Americans	17	9/5/1905	BSA	vs	PHA	W 3-2	35	3	4	0	0	0	1	7	1	0		49	4	0	6				.114	.279	.114	.393