Since 2018, 44 players are tied for the most strikeouts in a game, with 5 strikeouts. The first three are Austin Slater last Thursday, Tyler Stephenson on May 6 and Nick Castellanos on April 10.

Interpreted as:

most strikeouts by a player in a regular-season game since 2018

	NAME	SO	DATE	TM		OPP	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP
1	Austin Slater A. Slater	5	6/12/2025	CWS	@	HOU	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
2	Tyler Stephenson T. Stephenson	5	5/6/2025	CIN	@	ATL	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
3	Nick Castellanos N. Castellanos	5	4/10/2025	PHI	@	ATL	5	1	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
4	Jose Altuve J. Altuve	5	4/3/2025	HOU	@	MIN	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
5	Dylan Crews D. Crews	5	3/29/2025	WSH	vs	PHI	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
6	Jackson Chourio J. Chourio	5	3/27/2025	MIL	@	NYY	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
7	Aaron Judge A. Judge	5	9/28/2024	NYY	vs	PIT	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
8	Connor Norby C. Norby	5	9/26/2024	MIA	@	MIN	6	0	0	0	0	0	0	1	0	0	0	7	0	0	0	0	0	0
9	Mark Vientos M. Vientos	5	9/21/2024	NYM	vs	PHI	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
10	Randy Arozarena R. Arozarena	5	8/17/2024	SEA	@	PIT	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
11	Julio Rodríguez J. Rodríguez	5	8/11/2024	SEA	vs	NYM	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
12	Jake Burger J. Burger	5	7/4/2024	MIA	vs	BOS	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
13	Nolan Jones N. Jones	5	6/30/2024	COL	@	CWS	6	0	0	0	0	0	0	0	0	0	0	6	0	0	0	0	0	0
14	Ryan McMahon R. McMahon	5	9/16/2023	COL	vs	SFG	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
15	Jake Bauers J. Bauers	5	8/13/2023	NYY	@	MIA	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
16	Anthony Rizzo A. Rizzo	5	7/30/2023	NYY	@	BAL	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
17	LaMonte Wade Jr. L. Wade Jr.	5	5/26/2023	SFG	@	MIL	6	0	0	0	0	0	0	0	0	0	0	6	0	0	0	0	0	0
18	Jake Burger J. Burger	5	5/23/2023	CWS	@	CLE	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
19	Bryan De La Cruz B. De La Cruz	5	4/27/2023	MIA	@	ATL	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
20	Brandon Lowe B. Lowe	5	4/24/2023	TBR	vs	HOU	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
21	Dansby Swanson D. Swanson	5	4/14/2023	CHC	@	LAD	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
22	Ramón Urías R. Urías	5	4/1/2023	BAL	@	BOS	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
23	Max Muncy M. Muncy	5	3/30/2023	LAD	vs	ARI	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
24	Jonathan India J. India	5	9/11/2022	CIN	@	MIL	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
25	Tyler Naquin T. Naquin	5	8/19/2022	NYM	@	PHI	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0