Between the 2009 and 2012 seasons, the New York Yankees had the most wins by a team, with 390 wins.

Interpreted as:

most regular-season wins by a team in MLB 2009 to 2012

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	390	258	.602	648	22,269	3,445	6,003	1,147	99	912	3,314	2,517	263	4,464	454	131	25,363	10,084	2,158	131	183	136	550	.270	.348	.453	.801
2	Phillies	373	275	.576	648	22,282	2,989	5,713	1,131	135	701	2,876	2,142	253	4,337	439	96	25,078	9,217	1,967	236	165	209	432	.256	.326	.414	.740
3	Rangers	366	282	.565	648	22,410	3,234	6,117	1,177	116	796	3,075	1,936	178	4,272	506	173	24,899	9,914	2,089	168	207	139	482	.273	.333	.442	.775
4	Rays	361	287	.557	648	21,735	3,009	5,394	1,115	140	706	2,873	2,456	237	5,037	655	214	24,742	8,907	1,961	135	179	123	430	.248	.329	.410	.738
5	Braves	360	288	.556	648	21,955	2,814	5,556	1,119	91	610	2,665	2,307	165	4,753	299	131	24,877	8,687	1,820	292	158	186	499	.253	.327	.396	.722
6	Giants	360	288	.556	648	22,025	2,642	5,644	1,128	154	508	2,481	1,810	181	4,476	336	150	24,490	8,604	1,790	274	200	185	504	.256	.315	.391	.706
7	Cardinals	355	293	.548	648	22,161	2,993	5,931	1,177	106	631	2,841	2,144	208	4,238	302	148	24,972	9,213	1,914	287	172	260	555	.268	.336	.416	.751
8	Angels	352	296	.543	648	22,159	2,998	5,879	1,131	108	670	2,858	1,904	191	4,323	521	200	24,598	9,236	1,909	182	162	122	517	.265	.327	.417	.743
9	Tigers	350	299	.539	649	22,222	3,007	5,965	1,129	140	667	2,883	2,118	198	4,507	249	106	24,895	9,375	1,936	180	177	173	547	.268	.335	.422	.757
10	Reds	345	303	.532	648	22,130	2,867	5,679	1,133	104	701	2,731	2,069	231	4,863	373	160	24,915	9,123	1,938	317	168	177	414	.257	.324	.412	.737
11	Dodgers	343	304	.530	647	21,892	2,728	5,643	1,054	119	498	2,580	2,119	206	4,495	438	182	24,708	8,429	1,671	316	175	243	504	.258	.327	.385	.712
12	Red Sox	343	305	.529	648	22,503	3,299	6,065	1,384	98	791	3,141	2,252	212	4,565	393	129	25,273	10,018	2,273	104	202	161	508	.270	.339	.445	.784
13	Brewers	336	312	.519	648	22,120	3,032	5,782	1,150	140	751	2,901	2,103	298	4,770	401	133	24,936	9,465	2,041	254	161	167	468	.261	.332	.428	.759
14	White Sox	331	317	.511	648	21,967	2,878	5,673	989	86	726	2,756	1,937	290	4,136	463	219	24,520	9,012	1,801	167	159	103	524	.258	.324	.410	.735
15	Athletics	324	324	.500	648	22,011	2,780	5,505	1,130	112	553	2,630	2,113	192	4,588	528	161	24,647	8,518	1,795	135	196	81	475	.250	.319	.387	.706
16	Blue Jays	314	334	.485	648	22,237	3,012	5,610	1,190	90	850	2,879	2,017	203	4,627	385	136	24,736	9,530	2,130	104	175	118	461	.252	.318	.429	.746
17	Padres	312	336	.481	648	21,698	2,547	5,276	1,020	140	485	2,408	2,164	209	4,923	531	169	24,505	8,031	1,645	271	163	197	442	.243	.316	.370	.686
18	Rockies	312	336	.481	648	22,049	3,067	5,815	1,150	196	692	2,914	2,250	187	4,965	423	178	24,957	9,433	2,038	281	190	181	458	.264	.334	.428	.762
19	Twins	310	339	.478	649	22,225	2,918	5,865	1,118	136	548	2,757	2,089	174	4,105	380	136	24,832	8,899	1,802	153	191	143	570	.264	.329	.400	.730
20	Diamondbacks	310	338	.478	648	21,921	2,898	5,547	1,208	149	690	2,789	2,230	178	5,342	414	187	24,695	9,123	2,047	206	160	194	396	.253	.325	.416	.741
21	Marlins	308	340	.475	648	22,048	2,725	5,581	1,125	131	597	2,585	2,108	204	5,073	411	143	24,794	8,759	1,853	270	164	172	442	.253	.322	.397	.719
22	Nationals	306	341	.473	647	21,967	2,720	5,558	1,079	116	653	2,601	2,069	222	5,076	394	154	24,682	8,828	1,848	267	157	158	471	.253	.321	.402	.723
23	Mets	300	348	.463	648	21,968	2,695	5,667	1,156	149	470	2,557	2,102	175	4,358	461	161	24,726	8,531	1,775	291	190	201	475	.258	.325	.388	.713
24	Orioles	292	356	.451	648	22,317	2,774	5,757	1,114	69	698	2,646	1,873	195	4,504	291	125	24,655	9,103	1,881	106	164	105	591	.258	.319	.408	.727
25	Cubs	290	357	.448	647	21,958	2,659	5,532	1,141	128	595	2,516	1,943	211	4,858	274	133	24,478	8,714	1,864	227	139	140	506	.252	.317	.397	.714