most wins by a team vs one team in a single season since 2000

Since 2000, the Tampa Bay Rays, the Houston Astros and the Cleveland Indians are tied for the most wins against a team in a season, with 18 wins.

	TEAM	W	OPP	SEASON	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Rays	18	Orioles	2021	1	.947	19	679	150	199	35	6	40	144	74	6	163	7	4	764	366	81	0	5	1	7	.293	.365	.539	.904
2	Astros	18	Mariners	2019	1	.947	19	683	123	187	51	6	30	117	72	8	124	11	2	776	340	87	2	11	4	15	.274	.345	.498	.843
3	Indians	18	Tigers	2019	1	.947	19	653	116	197	48	5	29	111	67	5	143	21	7	738	342	82	5	8	3	13	.302	.367	.524	.891
4	Giants	17	Diamondbacks	2021	2	.895	19	674	126	201	47	7	33	123	71	7	142	7	1	764	361	87	7	5	6	8	.298	.369	.536	.904
5	Yankees	17	Orioles	2019	2	.895	19	673	151	204	34	2	61	147	88	5	134	4	2	769	425	97	0	3	2	17	.303	.386	.632	1.018
6	Indians	17	White Sox	2013	2	.895	19	645	118	182	35	3	25	114	73	10	138	18	4	743	298	63	3	12	3	11	.282	.358	.462	.820
7	Rangers	17	Astros	2013	2	.895	19	643	126	182	37	8	25	117	73	8	116	16	9	739	310	70	7	8	7	11	.283	.359	.482	.841
8	Athletics	17	Mariners	2006	2	.895	19	665	124	205	49	6	17	117	96	8	107	4	3	776	317	72	2	5	8	25	.308	.399	.477	.876
9	Phillies	16	Nationals	2022	3	.842	19	639	127	176	32	7	41	121	74	8	124	14	2	724	345	80	0	3	2	13	.275	.356	.540	.896
10	Blue Jays	16	Red Sox	2022	3	.842	19	699	125	218	42	3	24	124	64	6	157	13	3	777	338	69	1	7	1	15	.312	.371	.484	.855
11	Dodgers	16	Diamondbacks	2021	3	.842	19	651	124	191	36	5	36	118	84	13	137	9	1	764	345	77	8	8	4	20	.293	.381	.530	.911
12	Red Sox	16	Orioles	2018	3	.842	19	664	127	196	48	4	36	117	87	6	131	19	4	766	360	88	2	7	4	17	.295	.378	.542	.920
13	Red Sox	16	Orioles	2009	2	.889	18	663	130	222	44	4	29	128	75	10	101	16	3	758	361	77	3	7	5	11	.335	.407	.544	.951
14	Dodgers	16	Diamondbacks	2004	3	.842	19	677	118	191	30	4	27	112	79	11	149	20	4	782	310	61	10	5	13	8	.282	.364	.458	.822
15	Red Sox	16	Devil Rays	2002	3	.842	19	674	131	208	47	2	31	125	74	14	97	9	2	771	352	80	1	8	3	20	.309	.384	.522	.907
16	Dodgers	15	Giants	2022	4	.789	19	646	99	171	44	5	23	98	63	6	147	9	5	721	294	72	1	5	3	8	.265	.333	.455	.788
17	Marlins	15	Nationals	2022	4	.789	19	652	89	172	39	2	21	84	56	10	143	17	5	725	278	62	1	6	1	12	.264	.329	.426	.755
18	Mariners	15	Athletics	2021	4	.789	19	643	87	157	33	2	22	84	55	9	175	7	2	711	260	57	1	3	1	8	.244	.311	.404	.716
19	Athletics	15	Angels	2021	4	.789	19	611	86	144	29	2	21	78	82	16	153	8	3	722	240	52	3	10	6	15	.236	.337	.393	.729
20	Giants	15	Rockies	2021	4	.789	19	637	125	185	33	4	28	124	81	11	159	8	2	734	310	65	4	1	3	17	.290	.379	.487	.866
21	Brewers	15	Cubs	2021	4	.789	19	636	124	165	37	2	29	119	83	18	161	15	1	743	293	68	3	3	4	12	.259	.359	.461	.820
22	Brewers	15	Pirates	2019	4	.789	19	668	117	185	41	5	38	111	85	9	169	11	4	771	350	84	3	6	7	10	.277	.363	.524	.887
23	Nationals	15	Marlins	2019	4	.789	19	644	112	169	41	2	31	107	63	13	143	9	4	726	307	74	2	4	5	12	.262	.338	.477	.815
24	Braves	15	Marlins	2019	4	.789	19	631	87	143	29	3	26	86	84	9	164	5	2	732	256	58	4	4	11	17	.227	.324	.406	.730
25	Dodgers	15	Rockies	2019	4	.789	19	666	142	193	40	5	44	136	75	7	149	5	2	767	375	89	12	7	5	15	.290	.364	.563	.927