Kyle Freeland has allowed the most runs this season, with 46 runs.

Interpreted as:

pitcher most runs allowed in 1st inning this regular season

	NAME	R	SEASON	TM	G	W	L	W%	GS	ERA	SO	CG	SHO	SV	IP	H	ER	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Kyle Freeland K. Freeland	46	2025	COL	11	0	7	.000	11	5.86	44	0	0	0	55.1	80	36	5	13	1	0	1	256	1	7.16	2.11	3.38	0.81	17.2	5.1	1.68	.389	7.48	126	3.41	81	13.01	4.7
2	Germán Márquez G. Márquez	45	2025	COL	10	1	7	.125	10	7.66	26	0	0	0	47.0	61	40	4	18	4	0	0	219	4	4.98	3.45	1.44	0.77	11.9	8.2	1.68	.341	8.62	165	4.47	107	11.68	-1.3
3	Sandy Alcantara S. Alcantara	43	2025	MIA	10	2	7	.222	10	8.04	40	0	0	0	47.0	49	42	8	25	2	0	0	216	4	7.66	4.79	1.60	1.53	18.5	11.6	1.57	.291	8.23	192	5.30	133	9.38	-6.8
4	Tanner Houck T. Houck	41	2025	BOS	9	0	3	.000	9	8.04	32	0	0	0	43.2	57	39	10	17	5	0	0	203	2	6.60	3.50	1.88	2.06	15.8	8.4	1.69	.338	8.45	192	6.09	148	11.75	-9.5
5	Eduardo Rodriguez E. Rodriguez	41	2025	AZ	9	1	3	.250	9	7.05	52	0	0	0	44.2	58	35	8	18	0	0	0	211	2	10.48	3.63	2.89	1.61	24.6	8.5	1.70	.376	8.26	170	4.28	110	11.69	-2.1
6	Antonio Senzatela A. Senzatela	41	2025	COL	10	1	8	.111	10	6.34	25	0	0	0	49.2	84	35	9	14	1	0	0	239	1	4.53	2.54	1.79	1.63	10.5	5.9	1.97	.395	7.43	137	5.32	127	15.22	-5.8
7	Charlie Morton C. Morton	36	2025	BAL	12	0	7	.000	6	7.68	40	0	0	0	41.0	48	35	9	24	2	1	0	195	0	8.78	5.27	1.67	1.98	20.5	12.3	1.76	.325	7.90	199	5.87	147	10.54	-8.8
8	Trevor Williams T. Williams	36	2025	WSH	10	2	5	.286	10	6.39	41	0	0	0	49.1	62	35	7	15	2	0	0	224	1	7.48	2.74	2.73	1.28	18.3	6.7	1.56	.346	6.57	157	4.28	106	11.31	-1.3
9	Dean Kremer D. Kremer	36	2025	BAL	10	3	5	.375	10	5.50	40	0	0	0	55.2	62	34	10	15	1	0	0	242	4	6.47	2.43	2.67	1.62	16.5	6.2	1.38	.295	5.82	142	4.83	121	10.02	-5.4
10	Zac Gallen Z. Gallen	36	2025	AZ	11	3	6	.333	11	5.25	63	0	0	0	61.2	55	36	10	29	2	0	1	267	1	9.19	4.23	2.17	1.46	23.6	10.9	1.36	.276	5.25	127	4.64	120	8.03	-5.5
11	Aaron Nola A. Nola	35	2025	PHI	9	1	7	.125	9	6.16	52	0	0	0	49.2	59	34	11	16	3	0	0	220	1	9.42	2.90	3.25	1.99	23.6	7.3	1.51	.348	6.34	150	5.00	123	10.69	-5
12	Jordan Hicks J. Hicks	35	2025	SFG	11	1	5	.167	9	6.46	41	0	0	0	47.1	55	34	3	17	4	1	0	210	4	7.80	3.23	2.41	0.57	19.5	8.1	1.52	.359	6.65	162	3.49	91	10.46	1.8
13	Bowden Francis B. Francis	33	2025	TOR	10	2	6	.250	10	5.54	40	0	0	0	50.1	55	31	15	16	3	0	0	218	3	7.15	2.86	2.50	2.68	18.3	7.3	1.41	.278	5.90	142	6.48	160	9.83	-13.5
14	Luis Severino L. Severino	31	2025	ATH	11	1	4	.200	11	4.11	50	0	0	0	65.2	63	30	4	20	3	0	1	280	1	6.85	2.74	2.50	0.55	17.9	7.1	1.26	.291	4.25	104	3.39	83	8.63	4.9
15	Brady Singer B. Singer	31	2025	CIN	10	5	3	.625	10	4.88	46	0	0	0	51.2	48	28	7	22	1	0	0	221	0	8.01	3.83	2.09	1.22	20.8	10.0	1.35	.283	5.40	112	4.38	104	8.36	-0.7
16	Jack Kochanowicz J. Kochanowicz	31	2025	LAA	10	3	5	.375	10	5.03	35	0	0	0	53.2	58	30	9	27	3	0	2	236	2	5.87	4.53	1.30	1.51	14.8	11.4	1.58	.302	5.20	125	5.62	134	9.73	-8.2
17	Sean Burke S. Burke	31	2025	CWS	11	3	5	.375	10	4.33	39	0	0	0	54.0	49	26	9	30	4	0	0	241	2	6.50	5.00	1.30	1.50	16.2	12.4	1.46	.252	5.17	109	5.68	136	8.17	-8.6
18	José Berríos J. Berríos	30	2025	TOR	11	1	2	.333	11	4.22	56	0	0	0	64.0	61	30	10	26	3	0	1	272	1	7.88	3.66	2.15	1.41	20.6	9.6	1.36	.288	4.22	108	4.71	116	8.58	-4.6
19	Shane Baz S. Baz	30	2025	TBR	10	4	3	.571	10	4.94	52	0	0	0	54.2	54	30	10	22	3	0	0	233	0	8.56	3.62	2.36	1.65	22.3	9.4	1.39	.301	4.94	130	4.91	125	8.89	-6.2
20	Osvaldo Bido O. Bido	30	2025	ATH	9	2	4	.333	9	5.82	29	0	0	0	43.1	52	28	10	18	2	0	0	198	0	6.02	3.74	1.61	2.08	14.6	9.1	1.62	.302	6.23	147	6.11	150	10.80	-9.9
21	Chase Dollander C. Dollander	30	2025	COL	8	2	5	.286	8	6.28	38	0	0	0	38.2	37	27	10	18	2	0	0	172	1	8.84	4.19	2.11	2.33	22.1	10.5	1.42	.260	6.98	135	6.02	143	8.61	-7.4
22	Dylan Cease D. Cease	29	2025	SDP	10	1	3	.250	10	4.50	64	0	0	0	54.0	48	27	7	19	1	0	1	227	1	10.67	3.17	3.37	1.17	28.2	8.4	1.24	.301	4.83	114	3.49	88	8.00	2.8
23	Mitch Keller M. Keller	29	2025	PIT	11	1	6	.143	11	3.66	55	0	0	0	64.0	66	26	4	17	4	0	0	273	1	7.73	2.39	3.24	0.56	20.1	6.2	1.30	.321	4.08	87	3.15	79	9.28	6
24	Cal Quantrill C. Quantrill	29	2025	MIA	9	3	4	.429	9	6.37	29	0	0	0	41.0	48	29	6	15	1	0	0	177	1	6.37	3.29	1.93	1.32	16.4	8.5	1.54	.333	6.37	152	4.73	118	10.54	-3.3
25	Jeffrey Springs J. Springs	29	2025	ATH	10	5	3	.625	10	3.91	41	0	0	0	53.0	45	23	7	21	0	0	0	225	0	6.96	3.57	1.95	1.19	18.2	9.3	1.25	.244	4.92	99	4.43	109	7.64	-2.1