The Philadelphia Phillies have scored the most runs by an NL team in a loss, with 23 runs against the Cubs on August 25, 1922.

Interpreted as:

team most runs in a regular-season game in losses nl

	TEAM	R	L	DATE	TM		OPP	RESULT	W	L%	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Phillies	23	1	8/25/1922	PHN	@	CHC	L 23-26	0	1.000	52	26	4	2	0	19	11	0	5	1	1	66	34	6	3				.500	.587	.654	1.241
2	Cubs	22	1	5/17/1979	CHC	vs	PHI	L 22-23	0	1.000	56	26	3	1	6	22	3	0	4	0	0	59	49	10	0	0	0	2	.464	.492	.875	1.367
3	Marlins	17	1	7/4/2008	FLA	@	COL	L 17-18	0	1.000	47	22	7	0	2	17	6	2	4	0	0	56	35	9	1	0	1	1	.468	.545	.745	1.290
4	Phillies	17	1	8/3/1969	PHI	vs	CIN	L 17-19	0	1.000	47	21	4	1	3	17	4	0	6	1	0	51	36	8	0	0	1	2	.447	.490	.766	1.256
5	Beaneaters	17	1	4/19/1900	BSN	vs	PHI	L 17-19	0	1.000
6	Alleghenys	17	1	8/7/1890	PTN	@	CIN	L 17-23	0	1.000
7	Giants	17	1	5/23/1889	NYG	vs	CWS	L 17-18	0	1.000
8	Wolverines	17	1	7/28/1888	DET	@	CWS	L 17-21	0	1.000
9	White Stockings	17	1	8/14/1883	CWS	@	BUF	L 17-19	0	1.000
10	Cubs	16	1	4/17/1976	CHC	vs	PHI	L 16-18	0	1.000	48	19	5	0	3	16	6	3	7	0	0	58	33	8	1	0	1	1	.396	.491	.688	1.179
11	Giants	16	1	5/23/1970	SFG	vs	SDP	L 16-17	0	1.000	60	23	2	0	4	16	10	0	12	1	2	76	37	6	6	0	3	1	.383	.471	.617	1.088
12	Phillies	16	1	9/23/1930	PHN	vs	SLN	L 16-19	0	1.000	44	16	4	0	1	13	6	0	7	0	0	50	23	5	0				.364	.440	.523	.963
13	Phillies	16	1	5/18/1929	PHN	vs	BKN	L 16-20	0	1.000	41	17	6	0	2	16	12	0	6	2	0	53	29	8	0				.415	.547	.707	1.254
14	Cardinals	16	1	6/2/1900	STL	@	BSN	L 16-17	0	1.000
15	Bridegrooms	16	1	9/23/1896	BKN	@	PHI	L 16-17	0	1.000
16	Senators	16	1	8/8/1896	WSH	vs	BAL	L 16-21	0	1.000
17	Pirates	16	1	6/30/1893	PIT	vs	BKN	L 16-22	0	1.000
18	Colts	16	1	10/2/1891	CHI	vs	CNN	L 16-17	0	1.000
19	Cubs	15	1	5/14/2000	CHC	@	MON	L 15-16	0	1.000	46	21	1	0	3	14	4	1	9	6	0	51	31	4	0	0	0	0	.457	.510	.674	1.184
20	Dodgers	15	1	6/30/1996	LAD	@	COL	L 15-16	0	1.000	44	18	2	1	6	15	6	0	12	2	0	51	40	9	0	1	0	0	.409	.471	.909	1.380
21	Cubs	15	1	9/24/1985	CHC	vs	MON	L 15-17	0	1.000	46	20	2	0	3	15	4	0	4	1	1	51	31	5	0	1	0	0	.435	.471	.674	1.145
22	Reds	15	1	7/28/1977	CIN	@	CHC	L 15-16	0	1.000	58	19	5	0	5	14	10	0	12	6	0	69	39	10	1	0	4	2	.328	.426	.672	1.099
23	Cardinals	15	1	7/1/1956	STL	vs	CIN	L 15-19	0	1.000	52	23	2	0	3	14	7	1	3	1	0	60	34	5	0	0	0	1	.442	.517	.654	1.171
24	Cardinals	15	1	7/6/1934	SLN	vs	CIN	L 15-16	0	1.000	43	16	5	1	1	15	11	0	9	0	0	54	26	7	0			0	.372	.500	.605	1.105
25	Phillies	15	1	7/24/1930	PHN	vs	CHC	L 15-19	0	1.000	42	17	3	0	0	15	8	0	5	0	0	51	20	3	1				.405	.500	.476	.976