The New York Yankees had the most runs by an AL team in a home game in 2022, with 18 runs against the Cubs on June 12, 2022.

Interpreted as:

team most runs in a home regular-season game 2022 al

	TEAM	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	18	6/12/2022	NYY	vs	CHC	W 18-4	41	17	4	0	4	18	7	0	7	0	0	48	33	8	0	0	0	0	.415	.500	.805	1.305
2	Royals	15	8/28/2022	KCR	vs	SDP	W 15-7	42	18	3	0	2	14	6	1	9	3	0	50	27	5	0	1	0	0	.429	.500	.643	1.143
3	Orioles	15	8/19/2022	BAL	vs	BOS	W 15-10	40	18	6	0	5	15	3	1	6	0	0	45	39	11	0	1	0	0	.450	.489	.975	1.464
4	Yankees	14	9/21/2022	NYY	vs	PIT	W 14-2	35	11	7	0	3	14	5	0	13	0	0	40	27	10	0	0	0	0	.314	.400	.771	1.171
5	Yankees	14	7/16/2022	NYY	vs	BOS	W 14-1	37	12	2	0	4	14	8	2	9	0	0	47	26	6	0	0	0	0	.324	.468	.703	1.171
6	Tigers	14	6/18/2022	DET	vs	TEX	W 14-7	41	19	4	1	3	12	2	1	7	0	0	45	34	8	0	1	0	1	.463	.489	.829	1.318
7	Red Sox	13	9/27/2022	BOS	vs	BAL	W 13-9	34	11	1	0	1	12	8	3	7	0	0	46	15	2	0	1	1	3	.324	.478	.441	.919
8	Royals	13	9/25/2022	KCR	vs	SEA	W 13-12	35	14	4	0	1	13	7	0	6	1	0	42	21	5	0	0	0	2	.400	.500	.600	1.100
9	Red Sox	13	9/18/2022	BOS	vs	KCR	W 13-3	39	20	9	0	0	13	5	0	8	0	0	48	29	9	1	3	0	1	.513	.532	.744	1.276
10	White Sox	13	9/3/2022	CWS	vs	MIN	W 13-0	36	13	2	0	3	13	4	0	5	0	0	40	24	5	0	0	0	1	.361	.425	.667	1.092
11	Royals	13	8/7/2022	KCR	vs	BOS	W 13-5	31	11	3	2	1	12	6	1	6	0	1	40	21	6	0	2	0	0	.355	.450	.677	1.127
12	Yankees	13	7/17/2022	NYY	vs	BOS	W 13-2	37	14	2	0	2	13	6	3	6	2	0	47	22	4	0	1	0	1	.378	.489	.595	1.084
13	Astros	13	6/17/2022	HOU	vs	CWS	W 13-3	35	12	1	0	5	12	4	1	7	0	0	40	28	6	0	0	0	1	.343	.425	.800	1.225
14	Yankees	13	6/3/2022	NYY	vs	DET	W 13-0	35	15	3	1	4	13	5	1	7	0	0	41	32	8	0	0	0	2	.429	.512	.914	1.426
15	Tigers	13	4/23/2022	DET	vs	COL	W 13-0	42	20	1	0	1	13	3	0	7	0	0	45	24	2	0	0	0	1	.476	.511	.571	1.083
16	Mariners	13	4/23/2022	SEA	vs	KCR	W 13-7	40	16	6	0	2	13	8	0	10	2	0	48	28	8	0	0	0	0	.400	.500	.700	1.200
17	Astros	12	9/11/2022	HOU	vs	LAA	W 12-4	35	12	1	0	5	11	8	1	9	1	0	44	28	6	0	0	1	0	.343	.477	.800	1.277
18	Tigers	12	7/25/2022	DET	vs	SDP	W 12-4	37	13	1	0	4	11	3	0	5	0	0	41	26	5	0	1	0	0	.351	.390	.703	1.093
19	Blue Jays	12	6/4/2022	TOR	vs	MIN	W 12-3	39	16	2	1	3	11	6	1	5	2	0	47	29	6	0	1	0	1	.410	.489	.744	1.233
20	Red Sox	12	5/29/2022	BOS	vs	BAL	W 12-2	38	15	5	0	5	12	5	0	8	0	0	43	35	10	0	0	0	1	.395	.465	.921	1.386
21	Red Sox	12	5/19/2022	BOS	vs	SEA	W 12-6	39	16	4	0	3	11	4	1	7	1	0	44	29	7	0	0	0	1	.410	.477	.744	1.221
22	Twins	12	5/13/2022	MIN	vs	CLE	W 12-8	34	13	3	0	4	11	5	1	8	0	0	41	28	7	0	1	0	2	.382	.463	.824	1.287
23	Angels	12	5/10/2022	LAA	vs	TBR	W 12-0	41	18	4	0	4	12	1	0	6	1	0	43	34	8	0	1	0	0	.439	.442	.829	1.271
24	Yankees	12	4/26/2022	NYY	vs	BAL	W 12-8	38	13	1	1	5	12	2	0	9	0	0	40	31	7	0	0	0	0	.342	.375	.816	1.191
25	Guardians	11	9/19/2022	CLE	vs	MIN	W 11-4	38	14	1	2	3	10	5	1	4	4	0	44	28	6	0	0	0	1	.368	.455	.737	1.191