Since 2020, the Los Angeles Dodgers have the most wins by a team, with 551 wins.

Interpreted as:

teams with most regular-season wins in MLB since 2020

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Dodgers	551	319	.633	870	29,540	4,599	7,501	1,521	128	1,293	4,421	3,274	395	7,301	521	116	33,559	13,157	2,942	66	284	160	532	.254	.334	.445	.779
2	Astros	495	374	.570	869	29,581	4,132	7,576	1,477	89	1,098	3,972	2,758	357	6,559	443	133	32,995	12,525	2,664	66	233	108	673	.256	.325	.423	.748
3	Yankees	494	376	.568	870	28,912	4,170	6,977	1,244	77	1,300	3,983	3,360	314	7,569	514	152	32,874	12,275	2,621	55	233	146	687	.241	.325	.425	.749
4	Braves	493	376	.567	869	29,532	4,302	7,482	1,506	91	1,295	4,144	2,856	332	7,645	452	126	32,984	13,055	2,892	60	204	107	568	.253	.324	.442	.766
5	Brewers	492	378	.566	870	29,067	4,021	7,023	1,360	107	996	3,829	3,136	380	7,648	703	185	32,872	11,585	2,463	84	205	108	610	.242	.321	.399	.720
6	Rays	482	388	.554	870	29,264	3,990	7,147	1,458	128	1,000	3,789	2,803	376	7,847	763	230	32,687	11,861	2,586	45	199	81	511	.244	.316	.405	.722
7	Phillies	478	392	.549	870	29,402	4,145	7,447	1,451	140	1,115	3,982	2,853	338	7,433	630	141	32,917	12,523	2,706	103	221	130	571	.253	.324	.426	.750
8	Blue Jays	472	398	.543	870	29,533	4,138	7,625	1,562	87	1,085	3,976	2,779	330	6,603	429	136	32,925	12,616	2,734	79	204	88	675	.258	.327	.427	.754
9	Padres	470	400	.540	870	29,175	3,973	7,270	1,437	101	975	3,797	2,985	325	6,679	577	164	32,874	11,834	2,513	163	226	124	623	.249	.323	.406	.729
10	Mariners	470	400	.540	870	28,991	3,841	6,753	1,294	69	1,089	3,684	3,001	507	8,108	616	162	32,764	11,452	2,452	63	202	86	550	.233	.314	.395	.709
11	Guardians	463	406	.533	869	28,982	3,676	6,966	1,399	123	866	3,495	2,573	371	6,708	681	170	32,274	11,209	2,388	107	241	158	557	.240	.308	.387	.695
12	Giants	457	413	.525	870	29,120	3,891	6,988	1,394	128	1,029	3,725	2,960	385	7,746	342	100	32,794	11,725	2,551	95	234	115	611	.240	.316	.403	.719
13	Mets	451	419	.518	870	29,052	3,945	7,208	1,368	107	1,079	3,790	2,804	537	7,145	507	113	32,699	12,027	2,554	99	207	108	627	.248	.324	.414	.738
14	Cardinals	445	423	.513	868	29,049	3,798	7,169	1,409	92	968	3,637	2,746	413	7,009	484	142	32,541	11,666	2,469	104	229	90	577	.247	.318	.402	.720
15	Red Sox	442	428	.508	870	29,818	4,165	7,668	1,774	115	1,017	3,971	2,674	361	7,665	518	158	33,127	12,723	2,906	57	217	122	609	.257	.324	.427	.750
16	Cubs	437	433	.502	870	29,089	3,975	7,058	1,361	153	1,032	3,793	2,908	421	7,642	665	183	32,747	11,821	2,546	102	227	88	561	.243	.318	.406	.725
17	Orioles	427	443	.491	870	29,353	3,877	7,163	1,465	127	1,052	3,717	2,576	359	7,544	501	154	32,577	12,038	2,644	72	217	70	519	.244	.311	.410	.721
18	Twins	426	444	.490	870	29,255	3,892	7,118	1,443	105	1,104	3,706	2,791	442	7,618	371	114	32,753	12,083	2,652	50	215	75	632	.243	.317	.413	.730
19	Reds	418	452	.480	870	28,917	3,875	6,940	1,381	123	1,007	3,698	2,823	460	7,763	625	189	32,497	11,588	2,511	96	201	62	593	.240	.316	.401	.716
20	Tigers	417	451	.480	868	29,023	3,604	6,913	1,282	188	876	3,462	2,512	287	7,882	376	118	32,102	11,199	2,346	50	230	51	550	.238	.303	.386	.689
21	Diamondbacks	404	466	.464	870	29,275	4,073	7,199	1,493	186	966	3,876	2,903	373	7,095	575	147	33,003	11,962	2,645	171	281	92	575	.246	.319	.409	.728
22	Rangers	399	471	.459	870	29,329	3,804	7,029	1,320	101	1,011	3,627	2,631	300	7,402	593	161	32,519	11,584	2,432	55	204	81	519	.240	.307	.395	.702
23	Marlins	392	478	.451	870	29,240	3,484	7,115	1,329	123	832	3,316	2,392	319	7,463	628	180	32,254	11,186	2,284	105	198	89	624	.243	.306	.383	.688
24	Royals	389	481	.447	870	29,132	3,636	7,171	1,409	174	861	3,497	2,328	313	6,725	685	207	32,157	11,511	2,444	125	259	71	516	.246	.306	.395	.701
25	Angels	384	486	.441	870	29,100	3,687	6,879	1,268	120	1,087	3,529	2,636	390	7,990	470	169	32,404	11,648	2,475	94	184	124	583	.236	.307	.400	.707