Since 2020, the Los Angeles Dodgers have the most wins by a team, with 487 wins.

Interpreted as:

teams with most regular-season wins in MLB since 2020

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Dodgers	487	266	.647	753	25,592	4,033	6,533	1,343	116	1,123	3,880	2,865	352	6,321	465	100	29,111	11,477	2,582	56	246	134	459	.255	.336	.448	.784
2	Braves	440	312	.585	752	25,544	3,757	6,498	1,326	78	1,151	3,614	2,430	295	6,656	399	110	28,495	11,433	2,555	50	176	97	494	.254	.324	.448	.772
3	Astros	431	320	.574	751	25,550	3,626	6,567	1,295	82	953	3,488	2,429	303	5,603	380	114	28,546	10,885	2,330	58	206	98	581	.257	.326	.426	.752
4	Yankees	426	327	.566	753	24,982	3,579	6,010	1,073	63	1,104	3,411	2,905	284	6,511	413	124	28,417	10,521	2,240	49	197	108	609	.241	.324	.421	.745
5	Rays	426	327	.566	753	25,305	3,454	6,143	1,279	115	857	3,279	2,472	340	6,833	624	194	28,317	10,223	2,251	29	171	71	434	.243	.317	.404	.721
6	Brewers	416	337	.552	753	25,044	3,408	5,944	1,154	93	867	3,252	2,722	326	6,751	597	146	28,325	9,885	2,114	68	165	99	537	.237	.318	.395	.713
7	Phillies	408	344	.543	752	25,385	3,577	6,408	1,249	123	948	3,429	2,495	292	6,445	546	119	28,452	10,747	2,320	91	189	117	507	.252	.324	.423	.748
8	Padres	407	344	.542	751	25,180	3,468	6,277	1,248	89	862	3,313	2,616	279	5,813	505	143	28,395	10,289	2,199	125	195	111	549	.249	.324	.409	.733
9	Mariners	404	347	.538	751	24,944	3,281	5,757	1,116	62	910	3,148	2,628	442	7,043	500	138	28,235	9,727	2,088	47	174	60	474	.231	.313	.390	.703
10	Giants	402	351	.534	753	25,245	3,404	6,086	1,229	105	905	3,261	2,562	331	6,755	299	86	28,411	10,240	2,239	79	194	104	532	.241	.317	.406	.723
11	Guardians	400	351	.533	751	25,093	3,213	6,096	1,213	108	748	3,043	2,224	328	5,710	587	147	27,940	9,769	2,069	86	209	134	504	.243	.310	.389	.700
12	Blue Jays	400	353	.531	753	25,538	3,517	6,542	1,347	75	934	3,376	2,402	281	5,837	380	120	28,448	10,841	2,356	53	174	71	576	.256	.325	.425	.749
13	Mets	397	357	.527	754	25,123	3,389	6,231	1,188	99	907	3,246	2,410	476	6,168	394	100	28,265	10,338	2,194	85	171	86	548	.248	.324	.411	.735
14	Cardinals	392	359	.522	751	25,157	3,331	6,245	1,235	84	863	3,193	2,428	344	6,036	426	125	28,215	10,237	2,182	83	203	81	498	.248	.321	.407	.727
15	Twins	381	372	.506	753	25,315	3,399	6,179	1,267	90	955	3,239	2,425	379	6,612	282	89	28,350	10,491	2,312	41	190	68	555	.244	.317	.414	.732
16	Red Sox	375	379	.497	754	25,860	3,602	6,661	1,532	98	888	3,436	2,312	309	6,672	426	131	28,714	11,053	2,518	47	186	108	531	.258	.324	.427	.751
17	Cubs	372	382	.493	754	25,190	3,446	6,091	1,175	136	874	3,281	2,535	389	6,733	561	158	28,397	10,160	2,185	97	186	77	509	.242	.319	.403	.722
18	Orioles	367	385	.488	752	25,386	3,365	6,224	1,274	114	911	3,230	2,217	305	6,475	404	126	28,165	10,459	2,299	69	188	58	451	.245	.311	.412	.723
19	Tigers	360	392	.479	752	25,136	3,096	5,974	1,104	159	738	2,976	2,159	241	6,833	334	105	27,778	9,610	2,001	49	193	43	489	.238	.302	.382	.684
20	Reds	357	397	.473	754	25,016	3,372	5,980	1,207	103	889	3,226	2,462	427	6,758	570	173	28,157	10,060	2,199	87	165	51	512	.239	.316	.402	.718
21	Diamondbacks	348	405	.462	753	25,311	3,512	6,208	1,309	155	813	3,333	2,534	312	6,116	494	119	28,535	10,266	2,277	142	236	77	499	.245	.319	.406	.724
22	Rangers	342	412	.454	754	25,371	3,278	6,093	1,132	90	884	3,124	2,260	253	6,431	495	138	28,105	10,057	2,106	46	175	64	453	.240	.307	.396	.703
23	Royals	332	422	.440	754	25,239	3,142	6,201	1,194	162	732	3,014	2,010	258	5,951	613	179	27,845	9,915	2,088	105	233	59	442	.246	.305	.393	.698
24	Angels	330	421	.439	751	25,138	3,178	5,976	1,111	108	920	3,039	2,256	321	6,789	401	148	27,957	10,063	2,139	84	158	107	511	.238	.307	.400	.707
25	Marlins	330	422	.439	752	25,201	2,957	6,097	1,128	100	718	2,813	2,044	277	6,599	529	150	27,782	9,579	1,946	95	165	81	550	.242	.304	.380	.684