Since 2010, the Miami Marlins have lost the most games by a team, with 1,332 losses.

Interpreted as:

teams with the most regular-season losses since 2010

	TEAM	L	W	L%	G	W%	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Marlins	1,332	1,036	.563	2,368	.438	80,210	9,309	19,828	3,678	428	2,089	8,852	6,668	814	19,580	1,375	472	88,881	30,629	6,195	653	536	447	1,806	.247	.310	.382	.691
2	Rockies	1,324	1,047	.558	2,371	.442	81,120	10,998	21,190	4,213	591	2,635	10,518	6,937	680	19,901	1,246	499	90,011	34,490	7,439	681	593	475	1,734	.261	.322	.425	.748
3	White Sox	1,302	1,068	.549	2,370	.451	80,548	9,874	20,182	3,759	334	2,470	9,446	6,361	928	19,164	1,262	526	88,778	32,019	6,563	405	536	268	1,792	.251	.311	.398	.708
4	Royals	1,283	1,090	.541	2,373	.459	80,873	9,950	20,766	4,019	500	2,115	9,474	6,167	762	16,999	1,868	570	88,913	32,130	6,634	438	673	316	1,770	.257	.313	.397	.710
5	Pirates	1,269	1,101	.535	2,371	.465	79,916	9,619	19,588	3,875	460	2,175	9,183	7,194	912	19,451	1,312	565	89,218	30,908	6,510	637	559	455	1,659	.245	.313	.387	.699
6	Orioles	1,247	1,122	.526	2,369	.474	80,956	10,390	20,285	3,909	272	2,974	9,959	6,546	829	19,262	1,000	364	89,200	33,660	7,155	306	563	284	1,753	.251	.311	.416	.727
7	Reds	1,242	1,130	.524	2,372	.476	80,035	10,353	19,846	3,854	372	2,662	9,885	7,559	1,053	19,657	1,584	579	89,914	32,430	6,888	699	568	454	1,634	.248	.319	.405	.724
8	Diamondbacks	1,232	1,140	.519	2,372	.481	80,794	10,772	20,262	4,201	570	2,538	10,249	7,738	797	19,480	1,489	484	90,565	33,217	7,309	597	639	505	1,663	.251	.320	.411	.731
9	Twins	1,227	1,144	.518	2,371	.482	80,895	10,732	20,376	4,198	383	2,643	10,227	7,606	860	19,137	1,059	408	90,272	33,269	7,224	309	602	341	1,700	.252	.321	.411	.732
10	Tigers	1,226	1,141	.518	2,367	.482	80,848	10,293	20,749	4,008	503	2,382	9,864	6,975	710	19,237	985	403	89,461	32,909	6,893	307	621	398	1,820	.257	.319	.407	.726
11	Padres	1,224	1,146	.516	2,370	.484	79,339	9,768	19,198	3,689	400	2,356	9,281	7,438	760	19,578	1,624	531	88,758	30,755	6,445	642	579	438	1,618	.242	.311	.388	.699
12	Angels	1,219	1,151	.514	2,370	.486	80,156	10,371	19,927	3,810	352	2,687	9,884	7,154	896	18,445	1,352	512	89,195	32,502	6,849	387	602	431	1,819	.249	.315	.405	.721
13	Athletics	1,209	1,162	.510	2,371	.490	80,040	10,268	19,392	3,988	365	2,614	9,767	7,687	856	18,884	1,279	386	89,476	31,952	6,967	288	605	272	1,763	.242	.313	.399	.712
14	Mariners	1,209	1,161	.510	2,370	.490	79,932	9,831	19,183	3,637	292	2,626	9,390	7,399	953	20,035	1,424	509	89,164	31,282	6,555	339	541	316	1,596	.240	.310	.391	.701
15	Rangers	1,189	1,184	.501	2,373	.499	80,699	10,953	20,505	3,887	354	2,782	10,405	7,174	897	18,671	1,622	572	89,797	33,446	7,023	398	629	350	1,635	.254	.320	.414	.734
16	Nationals	1,186	1,185	.500	2,371	.500	80,094	10,442	20,330	4,004	359	2,539	9,931	7,482	886	18,575	1,590	502	89,757	32,669	6,902	683	612	503	1,728	.254	.322	.408	.730
17	Cubs	1,185	1,187	.500	2,373	.500	80,170	10,488	19,806	3,979	431	2,651	9,980	7,756	1,073	20,204	1,234	493	90,091	32,600	7,061	551	541	474	1,671	.247	.320	.407	.726
18	Mets	1,183	1,189	.499	2,372	.501	80,196	10,212	19,838	3,948	365	2,568	9,794	7,618	1,074	18,900	1,224	418	90,003	32,220	6,881	556	559	506	1,712	.247	.319	.402	.721
19	Phillies	1,177	1,194	.496	2,371	.504	80,611	10,344	20,084	3,915	445	2,556	9,880	7,349	861	19,174	1,437	388	89,932	32,557	6,916	574	537	520	1,631	.249	.317	.404	.721
20	Blue Jays	1,177	1,193	.497	2,370	.503	80,528	10,935	20,240	4,192	277	3,071	10,457	7,627	781	18,432	1,174	416	89,818	34,199	7,540	302	580	276	1,833	.251	.320	.425	.745
21	Giants	1,150	1,222	.485	2,372	.515	80,616	10,005	20,120	4,029	470	2,221	9,531	7,290	770	18,760	1,052	429	89,897	31,752	6,720	572	649	501	1,787	.250	.315	.394	.709
22	Astros	1,150	1,219	.485	2,369	.515	80,524	10,734	20,482	4,114	319	2,771	10,233	7,381	847	18,415	1,394	514	89,776	33,547	7,204	411	613	338	1,845	.254	.321	.417	.738
23	Brewers	1,133	1,240	.477	2,373	.523	79,919	10,526	19,825	3,878	383	2,774	10,038	7,768	957	20,088	1,790	518	89,783	32,791	7,035	610	529	453	1,753	.248	.320	.410	.730
24	Red Sox	1,126	1,247	.475	2,373	.525	82,364	11,702	21,763	4,865	354	2,757	11,136	7,784	836	18,919	1,330	406	91,883	35,607	7,976	250	649	501	1,839	.264	.332	.432	.764
25	Guardians	1,113	1,255	.470	2,368	.530	80,078	10,491	20,100	4,159	348	2,454	9,971	7,666	877	17,794	1,644	482	89,712	32,317	6,961	417	674	411	1,709	.251	.321	.404	.724