Since 1995, the New York Yankees have their most runs in a game on August 25, 2011 and on June 19, 2000, with 22 runs.

Interpreted as:

yankees most runs in a regular-season game since 1995

	TEAM	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	22	8/25/2011	NYY	vs	OAK	W 22-9	43	21	2	1	5	22	13	1	9	0	0	58	40	8	0	1	1	0	.488	.603	.930	1.534
2	Yankees	22	6/19/2000	NYY	@	BOS	W 22-1	47	19	4	1	5	21	7	0	4	1	0	55	40	10	0	1	1	0	.404	.473	.851	1.324
3	Yankees	21	7/28/2015	NYY	@	TEX	W 21-5	46	19	5	1	2	20	10	2	11	0	0	58	32	8	0	0	0	1	.413	.534	.696	1.230
4	Yankees	21	7/22/2007	NYY	vs	TBD	W 21-4	48	25	4	1	6	20	7	1	8	3	0	56	49	11	0	0	0	1	.521	.589	1.021	1.610
5	Yankees	21	8/23/1999	NYY	@	TEX	W 21-3	50	23	7	1	2	21	5	0	6	1	0	55	38	10	0	0	0	0	.460	.509	.760	1.269
6	Yankees	21	7/24/1999	NYY	vs	CLE	W 21-1	44	21	5	0	2	21	9	0	7	0	0	54	32	7	0	1	1	0	.477	.556	.727	1.283
7	Yankees	20	3/29/2025	NYY	vs	MIL	W 20-9	40	16	2	0	9	20	8	2	5	0	0	51	45	11	0	1	0	0	.400	.510	1.125	1.635
8	Yankees	20	9/15/2020	NYY	vs	TOR	W 20-6	41	16	5	0	6	20	7	2	9	0	0	50	39	11	0	0	0	0	.390	.500	.951	1.451
9	Yankees	20	8/30/2015	NYY	@	ATL	W 20-6	46	21	3	0	3	20	9	1	7	0	0	57	33	6	0	1	0	1	.457	.544	.717	1.261
10	Yankees	20	8/21/2009	NYY	@	BOS	W 20-11	49	23	8	1	2	20	5	0	5	0	0	54	39	11	0	0	0	1	.469	.519	.796	1.314
11	Yankees	20	6/21/2005	NYY	vs	TBD	W 20-11	46	23	4	1	6	20	4	0	5	0	0	51	47	11	0	1	1	0	.500	.529	1.022	1.551
12	Yankees	20	6/19/2002	NYY	@	COL	W 20-10	45	18	7	0	3	19	8	3	7	2	0	58	34	10	0	2	2	0	.400	.500	.756	1.256
13	Yankees	19	9/26/2008	NYY	@	BOS	W 19-8	44	20	7	0	3	18	5	2	5	1	0	54	36	10	0	3	0	1	.455	.500	.818	1.318
14	Yankees	19	4/18/2005	NYY	vs	TBD	W 19-8	45	20	4	0	3	19	7	2	3	0	0	54	33	7	0	0	1	0	.444	.537	.733	1.270
15	Yankees	19	7/25/2000	NYY	@	BAL	W 19-1	43	20	1	0	5	19	7	0	5	0	1	52	36	6	1	1	0	0	.465	.529	.837	1.367
16	Yankees	19	9/25/1996	NYY	vs	MIL	W 19-2	42	20	4	1	2	17	8	1	4	1	0	52	32	7	0	1	1	2	.476	.558	.762	1.320
17	Yankees	18	6/12/2022	NYY	vs	CHC	W 18-4	41	17	4	0	4	18	7	0	7	0	0	48	33	8	0	0	0	0	.415	.500	.805	1.305
18	Yankees	18	8/3/2011	NYY	@	CWS	W 18-7	48	23	4	2	2	18	2	1	9	1	0	52	37	8	0	1	0	1	.479	.500	.771	1.271
19	Yankees	18	7/2/2008	NYY	vs	TEX	W 18-7	41	16	4	0	2	18	7	1	0	1	0	49	26	6	0	0	0	1	.390	.490	.634	1.124
20	Yankees	18	8/28/2004	NYY	@	TOR	W 18-6	44	19	4	0	6	18	7	1	11	0	1	52	41	10	0	0	0	0	.432	.519	.932	1.451
21	Yankees	18	5/27/2004	NYY	@	BAL	W 18-5	46	21	6	0	2	18	4	2	5	0	0	54	33	8	0	2	0	1	.457	.500	.717	1.217
22	Yankees	18	8/26/1997	NYY	@	OAK	W 18-2	45	22	6	0	2	14	6	0	0	0	0	53	34	8	0	2	2	3	.489	.528	.756	1.284
23	Yankees	17	6/29/2019	NYY	@	BOS	W 17-13	45	19	7	0	3	17	6	0	11	0	0	51	35	10	0	0	0	1	.422	.490	.778	1.268
24	Yankees	17	7/30/2011	NYY	vs	BAL	W 17-3	48	24	6	1	2	17	4	0	7	0	0	52	38	9	0	0	0	1	.500	.538	.792	1.330
25	Yankees	17	7/22/2011	NYY	vs	OAK	W 17-7	38	17	1	0	2	17	9	1	10	2	0	49	24	3	0	1	0	1	.447	.551	.632	1.183