Zack Wheeler struck out his most hitters in a game against the Rays on May 29, 2021, with 14 strikeouts.

Interpreted as:

Zack Wheeler career high strikeouts in a regular-season game

	NAME	SO	DATE	TM		OPP	DEC	GS	ERA	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP
1	Zack Wheeler Z. Wheeler	14	5/29/2021	PHI	@	TBR		1	3.86	0	0	0	7.0	4	3	3	1	2	0	0	0	27	0
2	Zack Wheeler Z. Wheeler	13	4/18/2025	PHI	vs	MIA	W	1	2.57	0	0	0	7.0	5	2	2	1	0	0	0	0	26	0
3	Zack Wheeler Z. Wheeler	12	7/6/2025	PHI	vs	CIN	W	1	1.00	1	0	0	9.0	1	1	1	1	0	0	0	0	28	0
4	Zack Wheeler Z. Wheeler	12	5/27/2023	PHI	@	ATL	W	1	0.00	0	0	0	8.0	3	0	0	0	1	1	0	0	29	0
5	Zack Wheeler Z. Wheeler	12	6/10/2021	PHI	vs	ATL		1	0.00	0	0	0	8.0	4	0	0	0	0	0	0	0	27	1
6	Zack Wheeler Z. Wheeler	12	5/23/2021	PHI	vs	BOS	W	1	1.23	0	0	0	7.1	3	1	1	1	1	1	0	0	27	0
7	Zack Wheeler Z. Wheeler	12	8/15/2013	NYM	@	SDP		1	1.50	0	0	0	6.0	7	1	1	0	1	0	0	0	25	0
8	Zack Wheeler Z. Wheeler	11	9/28/2024	PHI	@	WSH		1	2.84	0	0	0	6.1	3	2	2	1	2	0	0	0	23	0
9	Zack Wheeler Z. Wheeler	11	5/6/2024	PHI	vs	SFG	W	1	0.00	0	0	0	7.0	4	0	1	0	1	0	0	0	26	1
10	Zack Wheeler Z. Wheeler	11	7/28/2023	PHI	@	PIT	W	1	1.35	0	0	0	6.2	3	1	1	0	1	0	0	0	24	0
11	Zack Wheeler Z. Wheeler	11	4/23/2023	PHI	vs	COL	W	1	4.50	0	0	0	6.0	3	3	3	0	3	1	0	0	25	1
12	Zack Wheeler Z. Wheeler	11	8/8/2021	PHI	vs	NYM	W	1	0.00	1	1	0	9.0	2	0	0	0	1	0	0	0	30	0
13	Zack Wheeler Z. Wheeler	11	5/10/2019	NYM	vs	MIA	W	1	2.57	0	0	0	7.0	9	2	2	0	1	0	0	0	32	0
14	Zack Wheeler Z. Wheeler	11	4/23/2019	NYM	vs	PHI	W	1	0.00	0	0	0	7.0	5	0	0	0	0	0	0	0	25	0
15	Zack Wheeler Z. Wheeler	10	8/2/2025	PHI	vs	DET	L	1	4.50	0	0	0	6.0	9	3	4	3	0	0	0	0	27	0
16	Zack Wheeler Z. Wheeler	10	7/21/2025	PHI	vs	BOS		1	3.00	0	0	0	6.0	7	2	2	1	0	1	0	0	24	0
17	Zack Wheeler Z. Wheeler	10	6/30/2025	PHI	vs	SDP	W	1	0.00	0	0	0	8.0	6	0	0	0	0	1	0	0	30	0
18	Zack Wheeler Z. Wheeler	10	4/2/2025	PHI	vs	COL	W	1	1.29	0	0	0	7.0	3	1	1	1	0	1	0	0	24	0
19	Zack Wheeler Z. Wheeler	10	4/14/2024	PHI	vs	PIT	L	1	7.20	0	0	0	5.0	5	4	5	1	3	0	0	0	24	2
20	Zack Wheeler Z. Wheeler	10	4/3/2024	PHI	vs	CIN	L	1	1.50	0	0	0	6.0	4	1	3	0	1	1	0	0	25	0
21	Zack Wheeler Z. Wheeler	10	9/1/2023	PHI	@	MIL		1	4.50	0	0	0	6.0	5	3	3	1	0	0	0	0	23	0
22	Zack Wheeler Z. Wheeler	10	8/26/2023	PHI	vs	STL	W	1	1.29	0	0	0	7.0	3	1	1	1	0	0	0	0	24	0
23	Zack Wheeler Z. Wheeler	10	5/23/2022	PHI	@	ATL	W	1	2.70	0	0	0	6.2	8	2	2	0	0	0	0	0	26	1
24	Zack Wheeler Z. Wheeler	10	8/25/2021	PHI	vs	TBR	L	1	5.63	0	0	0	8.0	10	5	7	2	0	0	0	0	35	0
25	Zack Wheeler Z. Wheeler	10	5/18/2021	PHI	vs	MIA		1	0.00	0	0	0	7.0	5	0	1	0	0	0	0	0	26	0

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Results may be incomplete. StatMuse has complete game-level data for strikeouts going back to the 1901 season.

Some of the information used here was obtained free of charge from Retrosheet.

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