Since 1960, Nolan Ryan has fanned the most hitters in a season, with 383 strikeouts in 1973.

Interpreted as:

most so/ (r) by season since 1960 25 gs by a player

	NAME	SO	R	GS	SEASON	TM	G	W	L	W%	ERA	CG	SHO	SV	IP	H	ER	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Nolan Ryan N. Ryan	383	113	39	1973	CAL	41	21	16	.568	2.87	26	4	1	326.0	238	104	18	162	7	2	2	1,355	15	10.57	4.47	2.36	0.50	28.3	12.0	1.23	.280	3.12	80	2.48	69	6.57	40.9
2	Sandy Koufax S. Koufax	382	90	41	1965	LAD	43	26	8	.765	2.04	27	8	2	335.2	216	76	26	71	5	2	4	1,297	11	10.24	1.90	5.38	0.70	29.5	5.5	0.86	.234	2.41	63	1.93	61	5.79	47.9
3	Randy Johnson R. Johnson	372	74	34	2001	ARI	35	21	6	.778	2.49	3	2	0	249.2	181	69	19	71	18	1	2	994	8	13.41	2.56	5.24	0.68	37.4	7.1	1.01	.315	2.67	55	2.12	48	6.52	63.9
4	Nolan Ryan N. Ryan	367	127	41	1974	CAL	42	22	16	.579	2.89	26	3	0	332.2	221	107	18	202	9	1	3	1,392	9	9.93	5.46	1.82	0.49	26.4	14.5	1.27	.255	3.44	85	2.97	84	5.98	20.2
5	Randy Johnson R. Johnson	364	86	35	1999	ARI	35	17	9	.654	2.48	12	2	0	271.2	207	75	30	70	9	0	3	1,079	4	12.06	2.32	5.20	0.99	33.7	6.5	1.02	.292	2.85	53	2.75	59	6.86	57.2
6	Randy Johnson R. Johnson	347	89	35	2000	ARI	35	19	7	.731	2.64	8	3	0	248.2	202	73	23	76	6	0	1	1,001	5	12.56	2.75	4.57	0.83	34.7	7.6	1.12	.326	3.22	56	2.53	53	7.31	61.1
7	Nolan Ryan N. Ryan	341	110	37	1977	CAL	37	19	16	.543	2.77	22	4	0	299.0	198	92	12	204	9	0	7	1,272	21	10.26	6.14	1.67	0.36	26.8	16.0	1.34	.263	3.31	72	3.11	79	5.96	27.9
8	Randy Johnson R. Johnson	334	78	35	2002	ARI	35	24	5	.828	2.32	8	4	0	260.0	197	67	26	71	13	0	1	1,035	3	11.56	2.46	4.70	0.90	32.3	6.9	1.03	.289	2.70	54	2.65	61	6.82	47
9	Randy Johnson R. Johnson	329	102	34	1998	TOT	34	19	11	.633	3.28	10	6	0	244.1	203	89	23	86	14	0	1	1,014	7	12.12	3.17	3.83	0.85	32.4	8.5	1.18	.320	3.76	72	2.89	65	7.48	42.2
10	Nolan Ryan N. Ryan	329	80	39	1972	CAL	39	19	16	.543	2.28	20	9	0	284.0	166	72	14	157	10	0	4	1,154	18	10.43	4.98	2.10	0.44	28.5	13.6	1.14	.236	2.54	79	2.48	83	5.26	16.6
11	Nolan Ryan N. Ryan	327	117	39	1976	CAL	39	17	18	.486	3.36	21	7	0	284.1	193	106	13	183	5	0	2	1,196	5	10.35	5.79	1.79	0.41	27.3	15.3	1.32	.269	3.70	99	2.91	85	6.11	16.5
12	Gerrit Cole G. Cole	326	66	33	2019	HOU	33	20	5	.800	2.50	0	0	0	212.1	142	59	29	48	3	0	0	817	4	13.82	2.03	6.79	1.23	39.9	5.9	0.89	.275	2.80	55	2.63	58	6.02	45
13	Sam McDowell S. McDowell	325	80	35	1965	CLE	42	17	11	.607	2.18	14	3	4	273.0	178	66	9	132	6	5	7	1,116	17	10.71	4.35	2.46	0.30	29.1	11.8	1.14	.262	2.64	63	2.08	58	5.87	45.4
14	Curt Schilling C. Schilling	319	96	35	1997	PHI	35	17	11	.607	2.97	7	2	0	254.1	208	84	25	58	5	0	3	1,009	5	11.29	2.05	5.50	0.88	31.6	5.7	1.05	.304	3.40	69	2.61	62	7.36	45.8
15	Sandy Koufax S. Koufax	317	74	41	1966	LAD	41	27	9	.750	1.73	27	5	0	323.0	241	62	19	77	0	0	4	1,274	7	8.83	2.15	4.12	0.53	24.9	6.0	0.98	.258	2.06	53	2.07	65	6.72	41.8
16	Curt Schilling C. Schilling	316	95	35	2002	ARI	36	23	7	.767	3.23	5	1	0	259.1	218	93	29	33	3	0	1	1,017	6	10.97	1.15	9.58	1.01	31.1	3.2	0.97	.297	3.30	75	2.39	55	7.57	54.3
17	Pedro Martinez P. Martinez	313	56	29	1999	BOS	31	23	4	.852	2.07	5	1	0	213.1	160	49	9	37	9	1	1	835	6	13.20	1.56	8.46	0.38	37.5	4.4	0.92	.323	2.36	42	1.38	30	6.75	79.4
18	J.R. Richard	313	98	38	1979	HOU	38	18	13	.581	2.71	19	4	0	292.1	220	88	13	98	3	0	5	1,175	19	9.64	3.02	3.19	0.40	26.6	8.3	1.09	.277	3.02	78	2.19	62	6.77	45.6
19	Steve Carlton S. Carlton	310	84	41	1972	PHI	41	27	10	.730	1.97	30	8	0	346.1	257	76	17	87	1	0	8	1,351	8	8.06	2.26	3.56	0.44	22.9	6.4	0.99	.256	2.18	56	2.00	59	6.68	53.5
20	Chris Sale C. Sale	308	73	32	2017	BOS	32	17	8	.680	2.90	1	0	0	214.1	165	69	24	43	8	0	0	851	3	12.93	1.81	7.16	1.01	36.2	5.1	0.97	.301	3.07	63	2.45	56	6.93	45.5
21	Randy Johnson R. Johnson	308	97	34	1993	SEA	35	19	8	.704	3.24	10	3	1	255.1	185	92	22	99	16	1	1	1,043	8	10.86	3.49	3.11	0.78	29.5	9.5	1.11	.273	3.42	74	3.04	70	6.52	36.2
22	Mickey Lolich M. Lolich	308	133	45	1971	DET	45	25	14	.641	2.92	29	4	0	376.0	336	122	36	92	7	0	2	1,538	7	7.37	2.20	3.35	0.86	20.0	6.0	1.14	.274	3.18	83	2.84	78	8.04	32.5
23	Mike Scott M. Scott	306	73	37	1986	HOU	37	18	10	.643	2.22	7	5	0	275.1	182	68	17	72	2	0	6	1,065	3	10.00	2.35	4.25	0.56	28.7	6.8	0.92	.247	2.39	63	2.15	61	5.95	43.6
24	Sandy Koufax S. Koufax	306	68	40	1963	LAD	40	25	5	.833	1.88	20	11	0	311.0	214	65	18	58	3	0	7	1,210	6	8.86	1.68	5.28	0.52	25.3	4.8	0.87	.238	1.97	62	1.85	62	6.19	41.9
25	Pedro Martinez P. Martinez	305	65	31	1997	MON	31	17	8	.680	1.90	13	4	0	241.1	158	51	16	67	9	0	5	947	3	11.37	2.50	4.55	0.60	32.2	7.1	0.93	.258	2.42	45	2.38	57	5.89	49