Monster Beverage (MNST) had the highest return between 2003 and 2011 by a large-cap US stock, returning 17,390.4%.

ASSET	YEARS	% RETURN
Monster Beverage (MNST)	2003-2011	17,390.43%
Deckers Outdoor (DECK)	2003-2011	6,748.83%
Apple (AAPL)	2003-2011	5,541.62%
Booking (BKNG)	2003-2011	4,711.84%
Banco Bradesco SA ADR (BBD)	2003-2011	4,478.23%
Intuitive Surgical (ISRG)	2003-2011	3,664.49%
Grupo Cibest (CIB)	2003-2011	3,490.02%
Ambev SA ADR (ABEV)	2003-2011	3,022.94%
Williams Companies (WMB)	2003-2011	2,531.71%
Sociedad Quimica y Minera de Chile SA ADR B (SQM)	2003-2011	2,407.84%
Southern Copper (SCCO)	2003-2011	2,169.93%
Alamos Gold (AGI)	2003-2011	2,108.32%
Chunghwa Telecom (CHT)	2003-2011	1,951.25%
U-Haul (UHAL)	2003-2011	1,912.02%
F5 Networks (FFIV)	2003-2011	1,874.33%
Akamai Technologies (AKAM)	2003-2011	1,693.33%
Illumina (ILMN)	2003-2011	1,687.64%
Baidu (BIDU)	2003-2011	1,664.7%
Vale SA ADR (VALE)	2003-2011	1,558.24%
Companhia de Saneamento Basico do Estado de Sao Paulo SABESP ADR (SBS)	2003-2011	1,469.14%
NetEase (NTES)	2003-2011	1,432.03%
Axon Enterprise (AXON)	2003-2011	1,417.04%
Credicorp (BAP)	2003-2011	1,413.32%
Itau Unibanco Banco (ITUB)	2003-2011	1,392.82%
Cummins (CMI)	2003-2011	1,353.36%

Large-cap stocks are treated as having a market cap of $10B+.