Arrowhead Pharmaceuticals (ARWR) had the best month in 2010 by a mid-cap US stock in March 2010, returning 111.1%.

ASSET	MONTH	% RETURN
Arrowhead Pharmaceuticals (ARWR)	March 2010	111.11%
Novanta (NOVT)	March 2010	102.04%
First Bancorp (FBP)	December 2010	84%
Vera Therapeutics (VERA)	January 2010	80%
Oruka Therapeutics (ORKA)	March 2010	79.28%
Uranium Energy (UEC)	November 2010	77.22%
Applied Digital (APLD)	December 2010	74.63%
Energy Fuels (UUUU)	October 2010	69.48%
Riot Blockchain (RIOT)	April 2010	69.33%
ACADIA Pharmaceuticals (ACAD)	December 2010	69.01%
Green Brick Partners (GRBK)	September 2010	68.65%
Energy Fuels (UUUU)	July 2010	64.89%
Energy Fuels (UUUU)	September 2010	61.26%
Catalyst Pharmaceuticals (CPRX)	April 2010	60.71%
Radian (RDN)	March 2010	57.98%
Applied Digital (APLD)	February 2010	55.33%
MakeMyTrip (MMYT)	August 2010	54.55%
Casella Waste Systems (CWST)	December 2010	52.8%
Radian (RDN)	February 2010	51.36%
Cirrus Logic (CRUS)	April 2010	51.31%
Western Alliance Bancorporation (WAL)	April 2010	51.04%
Popular (BPOP)	March 2010	50.78%
Applied Digital (APLD)	October 2010	49.25%
Silicon Motion Technology (SIMO)	March 2010	49%
Banner (BANR)	April 2010	47.97%

Mid-cap stocks are treated as having a market cap between $2B and $10B.