best performing large cap stocks 2021 to 2025

Regencell Bioscience (RGC) had the highest return between 2021 and 2025 by a large-cap US stock, returning 6,549.8%.

ASSET	YEARS	% RETURN
Regencell Bioscience (RGC)	2021-2025	6,549.78%
Celestica (CLS)	2021-2025	3,527.12%
Comfort Systems USA (FIX)	2021-2025	1,711.62%
Sterling Construction (STRL)	2021-2025	1,539.35%
NVIDIA (NVDA)	2021-2025	1,327.2%
Credo Technology (CRDO)	2021-2025	1,089.17%
FTAI Aviation (FTAI)	2021-2025	1,072.96%
Carpenter Technology (CRS)	2021-2025	1,051.23%
Permian Resources (PR)	2021-2025	960.95%
Modine Manufacturing (MOD)	2021-2025	957.92%
Applovin (APP)	2021-2025	862.6%
Constellation Energy (CEG)	2021-2025	861.45%
Embraer (EMBJ)	2021-2025	836.24%
Super Micro Computer (SMCI)	2021-2025	820.44%
Vistra Energy (VST)	2021-2025	813.32%
Broadcom (AVGO)	2021-2025	775.64%
Vertiv (VRT)	2021-2025	767.34%
IES (IESC)	2021-2025	733.55%
Targa Resources (TRGP)	2021-2025	660.85%
YPF Sociedad Anonima (YPF)	2021-2025	648.65%
Palantir Technologies (PLTR)	2021-2025	643.41%
Howmet Aerospace (HWM)	2021-2025	629.47%
Arista Networks (ANET)	2021-2025	621.03%
Mueller Industries (MLI)	2021-2025	596.62%
Cameco (CCJ)	2021-2025	588.15%

Large-cap stocks are treated as having a market cap of $10B+.

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