best performing stocks in the past 50 years with cap over 50 billion

Altria (MO) has had the highest return between September 29, 1975 and September 29, 2025 by a US stock with a market cap of $50B+, returning 16,427,400%.

ASSET DATE % RETURN
Altria (MO)
9/29/1975 - 9/29/2025
16,427,400%
National Grid PLC ADR (NGG)
9/29/1975 - 9/29/2025
4,208,723.53%
Home Depot (HD)
9/29/1975 - 9/29/2025
2,440,911.9%
Nike (NKE)
9/29/1975 - 9/29/2025
1,980,185.71%
McDonald’s (MCD)
9/29/1975 - 9/29/2025
1,589,691.67%
Natwest (NWG)
9/29/1975 - 9/29/2025
1,401,900%
Walmart (WMT)
9/29/1975 - 9/29/2025
1,199,434.88%
Progressive (PGR)
9/29/1975 - 9/29/2025
977,731.33%
Microsoft (MSFT)
9/29/1975 - 9/29/2025
945,297.41%
Oracle (ORCL)
9/29/1975 - 9/29/2025
557,892.13%
Suncor Energy (SU)
9/29/1975 - 9/29/2025
539,393.67%
Danaher (DHR)
9/29/1975 - 9/29/2025
459,701%
NVIDIA (NVDA)
9/29/1975 - 9/29/2025
444,264.09%
UnitedHealth (UNH)
9/29/1975 - 9/29/2025
307,114.29%
Apple (AAPL)
9/29/1975 - 9/29/2025
259,250.25%
Berkshire Hathaway (BRK.A)
9/29/1975 - 9/29/2025
258,417.24%
Fastenal (FAST)
9/29/1975 - 9/29/2025
253,545.83%
Adobe Systems (ADBE)
9/29/1975 - 9/29/2025
234,821.77%
Sherwin-Williams (SHW)
9/29/1975 - 9/29/2025
231,703.39%
Aflac (AFL)
9/29/1975 - 9/29/2025
212,825.43%
Amazon (AMZN)
9/29/1975 - 9/29/2025
180,195.32%
KLA-Tencor (KLAC)
9/29/1975 - 9/29/2025
174,602.89%
S&P Global (SPGI)
9/29/1975 - 9/29/2025
174,017.23%
Eaton (ETN)
9/29/1975 - 9/29/2025
162,814.44%
Applied Materials (AMAT)
9/29/1975 - 9/29/2025
157,977.52%