American International (AIG) had the lowest return between 2005 and 2010 by a US stock in the S&P 500 (GSPC), returning -95.4%.

ASSET	YEARS	% RETURN
American International (AIG)	2005-2010	-95.42%
Citigroup (C)	2005-2010	-88.45%
Builders FirstSource (BLDR)	2005-2010	-86.98%
Axon Enterprise (AXON)	2005-2010	-85.47%
Boston Scientific (BSX)	2005-2010	-77.74%
PulteGroup (PHM)	2005-2010	-75.7%
Regions Financial (RF)	2005-2010	-74.86%
Electronic Arts (EA)	2005-2010	-73.42%
KeyCorp (KEY)	2005-2010	-68.21%
Masco (MAS)	2005-2010	-65.35%
Huntington Bancshares (HBAN)	2005-2010	-65.07%
Bank of America (BAC)	2005-2010	-64.39%
Lennar (LEN)	2005-2010	-63.34%
Advanced Micro Devices (AMD)	2005-2010	-63%
Fifth Third Bancorp (FITB)	2005-2010	-62.82%
MGM Resorts International (MGM)	2005-2010	-59.17%
DR Horton (DHI)	2005-2010	-56.08%
Hartford Financial Services (HIG)	2005-2010	-55.46%
eBay (EBAY)	2005-2010	-52.5%
Blackstone (BX)	2005-2010	-51.12%
T-Mobile US (TMUS)	2005-2010	-49.68%
Take-Two Interactive Software (TTWO)	2005-2010	-47.57%
Interactive Brokers (IBKR)	2005-2010	-46%
Capital One Financial (COF)	2005-2010	-45.48%
Delta Air Lines (DAL)	2005-2010	-44.62%