best performing stock in the last 20 years with a market cap of 5 billion +

Natwest (NWG) has had the highest return between September 26, 2005 and September 26, 2025 by a US stock with a market cap of $5B+, returning 1,361,900%.

ASSET DATE % RETURN
Natwest (NWG)
9/26/2005 - 9/26/2025
1,361,900%
QXO (QXO)
9/26/2005 - 9/26/2025
946,400%
Ferguson (FERG)
9/26/2005 - 9/26/2025
779,726.99%
NVIDIA (NVDA)
9/26/2005 - 9/26/2025
70,467.91%
Netflix (NFLX)
9/26/2005 - 9/26/2025
34,965.15%
Tesla (TSLA)
9/26/2005 - 9/26/2025
33,324.65%
Booking (BKNG)
9/26/2005 - 9/26/2025
29,653.57%
Broadcom (AVGO)
9/26/2005 - 9/26/2025
28,358.93%
Apple (AAPL)
9/26/2005 - 9/26/2025
15,737.6%
Mastercard (MA)
9/26/2005 - 9/26/2025
15,370.83%
Transdigm (TDG)
9/26/2005 - 9/26/2025
14,802.27%
XPO Logistics (XPO)
9/26/2005 - 9/26/2025
14,494.87%
Nova (NVMI)
9/26/2005 - 9/26/2025
13,664.57%
Monolithic Power Systems (MPWR)
9/26/2005 - 9/26/2025
12,107.14%
RadNet (RDNT)
9/26/2005 - 9/26/2025
11,637.5%
MercadoLibre (MELI)
9/26/2005 - 9/26/2025
11,590.88%
Comfort Systems USA (FIX)
9/26/2005 - 9/26/2025
11,141.34%
Texas Pacific Land Trust (TPL)
9/26/2005 - 9/26/2025
10,428.61%
Amazon (AMZN)
9/26/2005 - 9/26/2025
10,177.97%
Coca-Cola Consolidated (COKE)
9/26/2005 - 9/26/2025
10,173.22%
HEICO (HEI.A)
9/26/2005 - 9/26/2025
9,630.18%
Axon Enterprise (AXON)
9/26/2005 - 9/26/2025
9,523.65%
Deckers Outdoor (DECK)
9/26/2005 - 9/26/2025
8,005.85%
Monster Beverage (MNST)
9/26/2005 - 9/26/2025
7,480.1%
NewMarket (NEU)
9/26/2005 - 9/26/2025
7,238.48%