Dwyane Wade had his most points in a game versus the Cavaliers on April 1, 2006, with 44 points.

Interpreted as:

dwayne wade most points in a regular-season game vs cavs

	NAME	PTS	DATE	TM		OPP	MIN	REB	AST	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF	+/-
1	Dwyane Wade D. Wade	44	4/1/2006	MIA	@	CLE	43	8	9	2	1	18	36	50.0	1	4	25.0	7	9	77.8	55.1	2	6	1	4	-1
2	Dwyane Wade D. Wade	42	1/21/2008	MIA	vs	CLE	40	6	7	3	1	17	29	58.6	1	3	33.3	7	8	87.5	64.6	3	3	4	3	-7
3	Dwyane Wade D. Wade	41	3/2/2009	MIA	vs	CLE	40	7	9	7	1	16	30	53.3	2	6	33.3	7	9	77.8	60.4	3	4	8	3	-7
4	Dwyane Wade D. Wade	41	2/1/2007	MIA	vs	CLE	42	4	5	3	2	9	20	45.0	0	1	0.0	23	24	95.8	67.1	0	4	12	0	+12
5	Dwyane Wade D. Wade	36	11/12/2009	MIA	vs	CLE	38	4	5	0	2	9	21	42.9	3	6	50.0	15	21	71.4	59.5	0	4	4	1	-4
6	Dwyane Wade D. Wade	35	3/12/2006	MIA	vs	CLE	45	9	7	2	1	11	26	42.3	0	0		13	18	72.2	51.6	3	6	2	5	+9
7	Dwyane Wade D. Wade	34	1/31/2011	MIA	vs	CLE	34	7	5	3	0	13	21	61.9	1	1	100.0	7	8	87.5	69.3	2	5	4	4	+17
8	Dwyane Wade D. Wade	33	12/17/2005	MIA	@	CLE	39	4	7	2	1	11	22	50.0	0	2	0.0	11	13	84.6	59.5	1	3	2	2	-12
9	Dwyane Wade D. Wade	32	3/16/2015	MIA	vs	CLE	31	2	2	5	0	13	18	72.2	0	0		6	8	75.0	74.3	0	2	3	2	+16
10	Dwyane Wade D. Wade	32	1/25/2010	MIA	vs	CLE	39	10	5	3	1	10	21	47.6	3	5	60.0	9	16	56.3	57.1	3	7	2	1	+2
11	Dwyane Wade D. Wade	31	12/25/2014	MIA	vs	CLE	37	5	5	2	1	12	28	42.9	2	5	40.0	5	5	100.0	51.3	1	4	1	0	+5
12	Dwyane Wade D. Wade	29	12/28/2008	MIA	@	CLE	40	4	8	2	0	12	25	48.0	0	2	0.0	5	7	71.4	51.6	0	4	2	2	-4
13	Dwyane Wade D. Wade	28	12/15/2010	MIA	vs	CLE	40	6	3	1	0	10	18	55.6	3	6	50.0	5	7	71.4	66.4	2	4	1	4	+15
14	Dwyane Wade D. Wade	28	11/4/2004	MIA	vs	CLE	41	6	5	3	3	10	20	50.0	0	0		8	10	80.0	57.4	1	5	2	1	+6
15	Dwyane Wade D. Wade	27	2/9/2007	MIA	@	CLE	39	1	7	2	2	10	17	58.8	0	0		7	9	77.8	64.4	1	0	7	2	-21
16	Dwyane Wade D. Wade	26	2/7/2012	MIA	vs	CLE	35	4	6	3	1	9	17	52.9	0	1	0.0	8	8	100.0	63.4	1	3	4	2	+2
17	Dwyane Wade D. Wade	25	10/30/2015	MIA	@	CLE	30	4	3	2	1	8	15	53.3	1	2	50.0	8	8	100.0	67.5	0	4	7	4	+4
18	Dwyane Wade D. Wade	25	3/7/2009	MIA	@	CLE	41	8	12	4	0	9	23	39.1	2	4	50.0	5	5	100.0	49.6	1	7	3	2	+3
19	Dwyane Wade D. Wade	24	12/2/2016	CHI	vs	CLE	37	5	4	2	0	11	23	47.8	1	4	25.0	1	2	50.0	50.3	3	2	4	2	0
20	Dwyane Wade D. Wade	24	3/19/2016	MIA	vs	CLE	28	4	4	1	0	10	17	58.8	0	0		4	4	100.0	64.0	2	2	2	1	+28
21	Dwyane Wade D. Wade	24	12/14/2013	MIA	vs	CLE	34	6	3	1	0	9	15	60.0	0	0		6	9	66.7	63.3	3	3	1	3	-13
22	Dwyane Wade D. Wade	24	2/24/2013	MIA	vs	CLE	38	5	6	1	2	11	22	50.0	0	0		2	3	66.7	51.5	0	5	1	3	-6
23	Dwyane Wade D. Wade	24	3/29/2011	MIA	@	CLE	43	4	6	3	2	8	20	40.0	2	4	50.0	6	8	75.0	51.0	3	1	3	3	-12
24	Dwyane Wade D. Wade	24	2/4/2010	MIA	@	CLE	39	3	9	4	0	11	26	42.3	1	3	33.3	1	2	50.0	44.6	3	0	6	4	-16
25	Dwyane Wade D. Wade	24	2/2/2006	MIA	vs	CLE	35	4	6	4	1	11	20	55.0	0	0		2	3	66.7	56.3	0	4	3	4	+30