James Harden has his most career points per game against the Wizards, with 27.3 per game.

james harden highest career ppg by opponent

OPP	PPG	GP	MPG	RPG	APG	SPG	BPG	TPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	MIN	PTS	REB	AST	STL	BLK	TOV	PF	+/-
Wizards	27.3	29	35.2	5.3	7.4	1.6	0.6	3.9	8.5	17.4	48.8	3.0	7.5	40.4	7.3	8.1	89.8	1,021	793	153	215	47	17	113	69	+137
76ers	27.2	25	35.0	6.8	7.5	1.4	0.7	4.3	8.4	17.8	47.3	2.7	7.4	37.0	7.6	8.6	88.0	874	680	170	188	34	18	107	57	+136
Thunder	26.8	35	37.2	6.3	7.8	1.6	0.7	4.0	7.7	18.9	40.8	3.1	9.2	34.2	8.3	9.6	86.3	1,302	939	222	272	57	24	140	96	-51
Knicks	26.4	31	34.9	6.5	8.1	1.8	0.4	3.2	7.8	16.9	46.5	2.9	8.0	36.1	7.8	8.9	87.7	1,083	818	201	252	56	12	100	71	+287
Lakers	26.2	50	34.8	5.1	7.3	1.6	0.6	3.7	8.0	17.5	46.0	2.6	7.2	36.2	7.5	8.8	85.3	1,739	1,310	257	363	82	30	186	125	+231
Trail Blazers	25.8	46	35.2	5.5	6.5	1.5	0.5	3.7	7.9	17.2	45.9	2.8	7.3	37.8	7.3	8.6	85.1	1,618	1,189	252	300	69	21	168	128	+135
Suns	25.5	42	35.0	6.0	6.5	1.7	0.6	3.7	7.2	15.9	45.1	2.9	8.0	36.3	8.3	9.8	84.7	1,471	1,073	254	275	72	25	157	116	+316
Hawks	25.5	24	34.7	5.8	7.7	1.4	0.5	3.6	7.3	16.3	44.6	2.9	7.6	38.5	8.1	9.3	87.8	833	613	139	184	34	13	86	53	+96
Kings	25.2	46	33.1	5.6	6.9	1.6	0.5	3.8	7.6	16.6	45.9	3.2	8.2	39.0	6.8	7.8	86.4	1,525	1,160	259	316	75	25	175	102	+358
Pacers	24.8	32	36.5	5.8	8.3	1.6	0.5	3.5	6.9	16.3	42.7	3.0	8.4	35.8	7.9	9.0	87.5	1,169	793	184	264	51	17	113	84	+197
Bucks	24.8	30	35.6	5.7	6.9	1.7	0.6	4.0	7.8	16.6	46.8	2.7	7.2	37.8	6.5	7.7	84.4	1,068	743	171	208	50	18	121	83	+38
Magic	24.7	30	35.7	6.6	7.4	1.8	0.4	3.7	7.4	17.1	43.1	2.6	8.2	31.7	7.4	8.7	85.4	1,071	742	198	221	53	13	112	79	+121
Raptors	24.7	29	37.3	5.4	8.1	1.3	0.6	3.9	7.4	16.2	45.5	2.3	6.7	34.0	7.7	8.7	88.4	1,083	716	157	234	37	16	113	85	+73
Cavaliers	24.6	32	36.0	5.7	8.2	1.8	0.4	3.9	6.9	14.9	46.5	3.0	7.5	40.2	7.7	8.9	85.7	1,153	786	181	262	57	14	125	73	+206
Hornets	24.2	26	35.2	6.6	8.2	1.3	0.5	3.5	7.2	16.7	43.0	2.7	7.8	34.7	7.2	8.4	85.3	915	628	171	213	35	14	92	72	+176
Spurs	24.1	45	34.7	5.6	6.6	1.2	0.6	3.4	7.6	17.2	44.1	2.4	6.9	35.5	6.5	7.7	84.4	1,559	1,086	253	297	55	26	151	115	+51
Nets	24.1	24	34.9	5.8	6.6	1.5	0.6	3.4	7.0	16.3	43.3	2.8	7.5	37.2	7.2	8.2	88.3	839	578	140	158	36	14	81	58	+45
Heat	23.8	30	35.0	5.6	6.9	1.3	0.6	3.7	6.8	15.3	44.3	3.1	8.1	38.4	7.1	8.1	87.6	1,049	713	168	206	40	17	110	68	+104
Pelicans	23.7	46	33.6	5.1	7.3	1.4	0.6	3.7	7.2	16.2	44.6	2.6	7.7	33.4	6.7	7.7	86.2	1,547	1,091	236	334	64	28	169	114	+166
Warriors	23.5	43	35.1	5.4	7.0	1.7	0.5	3.0	7.0	16.5	42.5	3.0	8.0	37.0	6.5	7.6	85.6	1,510	1,010	234	302	71	22	131	106	+69
Nuggets	23.3	45	34.0	5.0	6.6	1.4	0.5	3.7	6.6	15.4	42.7	2.6	7.1	37.0	7.5	9.1	82.9	1,528	1,049	226	299	65	22	165	112	+141
Pistons	23.2	29	34.4	7.1	8.6	1.3	0.8	3.9	7.0	16.2	43.3	2.4	6.9	35.2	6.8	7.9	86.0	999	673	205	249	39	23	112	71	+195
Grizzlies	23.1	47	34.1	5.3	6.4	1.3	0.9	3.6	6.5	14.7	44.2	2.9	7.2	40.8	7.2	8.4	85.1	1,603	1,087	249	300	61	42	170	105	+192
Jazz	23.1	42	32.7	4.8	5.5	1.4	0.5	3.5	7.0	15.3	46.0	2.2	6.5	33.8	6.8	7.9	85.8	1,373	969	203	232	58	21	148	115	+253
Timberwolves	23.1	47	33.6	4.9	7.4	1.4	0.6	3.7	6.8	16.2	41.9	2.9	7.9	37.4	6.6	7.6	85.8	1,578	1,084	229	350	68	28	173	113	+125