Kobe Bryant and Joel Embiid had a plus/minus of +25.

Interpreted as:

most plus minus points by a player in a regular-season game

	NAME	+/-	PTS	DATE	TM		OPP	MIN	REB	AST	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF
1	Kobe Bryant K. Bryant	+25	81	1/22/2006	LAL	vs	TOR	42	6	2	3	1	28	46	60.9	7	13	53.8	18	20	90.0	73.9	2	4	3	1
2	Luka Dončić L. Dončić	+13	73	1/26/2024	DAL	@	ATL	45	10	7	1	0	25	33	75.8	8	13	61.5	15	16	93.8	91.2	0	10	4	1
3	Damian Lillard D. Lillard	+21	71	2/26/2023	POR	vs	HOU	39	6	6	0	0	22	38	57.9	13	22	59.1	14	14	100.0	80.4	1	5	2	0
4	Donovan Mitchell D. Mitchell	+19	71	1/2/2023	CLE	vs	CHI	50	8	11	0	1	22	34	64.7	7	15	46.7	20	25	80.0	78.9	3	5	4	3
5	Joel Embiid J. Embiid	+11	70	1/22/2024	PHI	vs	SAS	37	18	5	1	1	24	41	58.5	1	2	50.0	21	23	91.3	68.5	9	9	1	2
6	Devin Booker D. Booker	-6	70	3/24/2017	PHX	@	BOS	45	8	6	3	1	21	40	52.5	4	11	36.4	24	26	92.3	68.0	2	6	5	3
7	Kobe Bryant K. Bryant	+4	65	3/16/2007	LAL	vs	POR	50	7	3	3	0	23	39	59.0	8	12	66.7	11	12	91.7	73.4	1	6	2	3
8	Giannis Antetokounmpo G. Antetokounmpo	+29	64	12/13/2023	MIL	vs	IND	37	14	3	4	1	20	28	71.4	0	3	0.0	24	32	75.0	76.0	3	11	4	1
9	Devin Booker D. Booker	+1	62	1/26/2024	PHX	@	IND	38	5	4	1	2	22	37	59.5	6	12	50.0	12	13	92.3	72.6	0	5	4	2
10	Karl-Anthony Towns K. Towns	0	62	1/22/2024	MIN	vs	CHA	38	8	2	0	0	21	35	60.0	10	15	66.7	10	14	71.4	75.3	3	5	7	2
11	Stephen Curry S. Curry	+20	62	1/3/2021	GSW	vs	POR	36	5	4	0	0	18	31	58.1	8	16	50.0	18	19	94.7	78.8	1	4	5	0
12	Carmelo Anthony C. Anthony	+34	62	1/24/2014	NYK	vs	CHA	39	13	0	0	0	23	35	65.7	6	11	54.5	10	10	100.0	78.7	1	12	0	1
13	Kobe Bryant K. Bryant	+35	62	12/20/2005	LAL	vs	DAL	33	8	0	3	0	18	31	58.1	4	10	40.0	22	25	88.0	73.8	3	5	2	3
14	Tracy McGrady T. McGrady	+10	62	3/10/2004	ORL	vs	WAS	46	10	5	1	0	20	37	54.1	5	14	35.7	17	26	65.4	64.0	3	7	6	1
15	Nikola Jokić N. Jokić	+2	61	4/1/2025	DEN	vs	MIN	53	10	10	2	0	18	29	62.1	6	11	54.5	19	24	79.2	77.1	2	8	4	5
16	Jalen Brunson J. Brunson	+20	61	3/29/2024	NYK	@	SAS	43	4	6	1	0	25	47	53.2	5	13	38.5	6	6	100.0	61.4	1	3	1	2
17	Damian Lillard D. Lillard	+8	61	8/11/2020	POR	@	DAL	41	5	8	1	0	17	32	53.1	9	17	52.9	18	18	100.0	76.4	2	3	3	2
18	Damian Lillard D. Lillard	+13	61	1/20/2020	POR	vs	GSW	45	10	7	1	0	17	37	45.9	11	20	55.0	16	16	100.0	69.3	0	10	2	1
19	James Harden J. Harden	+18	61	3/22/2019	HOU	vs	SAS	37	7	1	3	0	19	34	55.9	9	13	69.2	14	17	82.4	73.5	2	5	3	3
20	James Harden J. Harden	+19	61	1/23/2019	HOU	@	NYK	40	15	4	5	0	17	38	44.7	5	20	25.0	22	25	88.0	62.2	6	9	5	3
21	LeBron James L. James	+16	61	3/3/2014	MIA	vs	CHA	41	7	4	0	0	22	33	66.7	8	10	80.0	9	12	75.0	79.7	3	4	2	2
22	Kobe Bryant K. Bryant	+19	61	2/2/2009	LAL	@	NYK	37	0	3	0	1	19	31	61.3	3	6	50.0	20	20	100.0	76.6	0	0	2	1
23	Shaquille O'Neal S. O'Neal	+16	61	3/6/2000	LAL	@	LAC	45	23	3	0	0	24	35	68.6	0	0		13	22	59.1	68.3	7	16	4	2
24	De'Aaron Fox D. Fox	+1	60	11/15/2024	SAC	vs	MIN	44	3	7	3	1	22	35	62.9	6	10	60.0	10	11	90.9	75.3	2	1	6	3
25	Stephen Curry S. Curry	-1	60	2/3/2024	GSW	@	ATL	41	6	4	0	1	22	38	57.9	10	23	43.5	6	6	100.0	73.8	1	5	2	1