Jamal Murray had the most points in a road game versus the Cavaliers in 2020-21, with 50 points on February 19, 2021.

Interpreted as:

most points by a player in a regular-season game vs at cavs 2021

	NAME	PTS	DATE	TM		OPP	MIN	REB	AST	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF	+/-
1	Jamal Murray J. Murray	50	2/19/2021	DEN	@	CLE	38	6	2	2	0	21	25	84.0	8	10	80.0	0	0		100.0	0	6	1	4	+24
2	LeBron James L. James	46	1/25/2021	LAL	@	CLE	38	8	6	2	2	19	26	73.1	7	11	63.6	1	2	50.0	85.6	0	8	3	1	+11
3	Gary Trent Jr. G. Trent Jr.	44	4/10/2021	TOR	@	CLE	33	7	4	1	0	17	19	89.5	7	9	77.8	3	3	100.0	108.3	0	7	1	2	+31
4	Terry Rozier T. Rozier	42	12/23/2020	CHA	@	CLE	38	3	2	2	1	15	23	65.2	10	16	62.5	2	4	50.0	84.8	1	2	3	5	-4
5	Zion Williamson Z. Williamson	38	4/11/2021	NOP	@	CLE	36	9	4	0	2	16	22	72.7	0	0		6	8	75.0	74.5	2	7	4	3	+7
6	Kyrie Irving K. Irving	38	1/22/2021	BKN	@	CLE	31	1	5	0	1	14	24	58.3	4	9	44.4	6	6	100.0	71.3	1	0	2	3	-11
7	Kevin Durant K. Durant	38	1/20/2021	BKN	@	CLE	50	12	8	1	4	12	25	48.0	3	9	33.3	11	13	84.6	61.8	1	11	2	2	+2
8	Kyrie Irving K. Irving	37	1/20/2021	BKN	@	CLE	48	2	3	1	3	15	28	53.6	3	8	37.5	4	5	80.0	61.3	1	1	4	4	-7
9	Paul George P. George	36	2/3/2021	LAC	@	CLE	34	4	6	0	0	13	20	65.0	8	9	88.9	2	3	66.7	84.4	0	4	0	4	+29
10	Stephen Curry S. Curry	33	4/15/2021	GSW	@	CLE	35	4	5	0	2	12	25	48.0	4	13	30.8	5	5	100.0	60.7	0	4	4	3	+5
11	Giannis Antetokounmpo G. Antetokounmpo	33	2/5/2021	MIL	@	CLE	33	12	4	1	4	13	25	52.0	1	3	33.3	6	8	75.0	57.9	2	10	3	3	+15
12	Damian Lillard D. Lillard	32	5/5/2021	POR	@	CLE	31	3	9	2	0	10	17	58.8	6	10	60.0	6	7	85.7	79.7	0	3	2	1	+14
13	Devin Booker D. Booker	31	5/4/2021	PHX	@	CLE	40	6	5	1	0	14	27	51.9	1	6	16.7	2	2	100.0	55.6	4	2	0	5	+12
14	Shai Gilgeous-Alexander S. Gilgeous-Alexander	31	2/21/2021	OKC	@	CLE	36	4	9	1	0	9	15	60.0	3	3	100.0	10	12	83.3	76.4	0	4	3	3	+10
15	De'Aaron Fox D. Fox	30	3/22/2021	SAC	@	CLE	38	6	6	2	0	13	23	56.5	1	5	20.0	3	6	50.0	58.5	0	6	3	4	+17
16	Jayson Tatum J. Tatum	29	5/12/2021	BOS	@	CLE	35	8	1	2	2	11	26	42.3	1	6	16.7	6	8	75.0	49.1	1	7	2	3	-5
17	Jayson Tatum J. Tatum	29	3/17/2021	BOS	@	CLE	37	5	3	2	1	11	24	45.8	3	13	23.1	4	5	80.0	55.3	0	5	1	3	-8
18	Malcolm Brogdon M. Brogdon	29	3/3/2021	IND	@	CLE	35	4	3	2	0	12	15	80.0	3	3	100.0	2	3	66.7	88.8	2	2	5	1	-8
19	Tyrese Haliburton T. Haliburton	28	3/22/2021	SAC	@	CLE	36	1	2	1	1	11	15	73.3	4	5	80.0	2	2	100.0	88.2	0	1	1	2	+11
20	Jaylen Brown J. Brown	28	3/17/2021	BOS	@	CLE	39	3	4	2	3	11	26	42.3	2	10	20.0	4	8	50.0	47.4	1	2	2	4	+2
21	Trae Young T. Young	28	2/23/2021	ATL	@	CLE	38	7	12	0	1	9	27	33.3	1	7	14.3	9	13	69.2	42.8	3	4	5	2	+7
22	Julius Randle J. Randle	28	1/15/2021	NYK	@	CLE	38	6	6	0	0	11	20	55.0	2	4	50.0	4	5	80.0	63.1	1	5	1	3	-1
23	Julius Randle J. Randle	28	12/29/2020	NYK	@	CLE	44	12	11	1	0	9	16	56.3	4	4	100.0	6	10	60.0	68.6	1	11	9	4	+3
24	Gordon Hayward G. Hayward	28	12/23/2020	CHA	@	CLE	36	4	7	1	0	11	18	61.1	4	8	50.0	2	2	100.0	74.2	0	4	3	4	-2
25	Brandon Ingram B. Ingram	27	4/11/2021	NOP	@	CLE	36	4	8	1	0	8	18	44.4	3	6	50.0	8	8	100.0	62.7	1	3	5	2	-1