Michael Jordan has the most points in a game versus Shaquille O'Neal, with 64 points on January 16, 1993.

Interpreted as:

most points by a player scored vs shaq in a regular-season game

	NAME	PTS	DATE	TM		OPP	MIN	REB	AST	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF	+/-
1	Michael Jordan M. Jordan	64	1/16/1993	CHI	vs	ORL	47	6	1	5	0	27	49	55.1	1	5	20.0	9	11	81.8	59.4	4	2	2	5
2	Glen Rice G. Rice	56	4/15/1995	MIA	vs	ORL	45	4	0	0	0	20	27	74.1	7	8	87.5	9	10	90.0	89.2	1	3	2	4
3	Brandon Roy B. Roy	52	12/18/2008	POR	vs	PHX	44	5	6	0	1	14	27	51.9	5	7	71.4	19	21	90.5	71.7	1	4	0	1	+12
4	Jamal Crawford J. Crawford	52	1/26/2007	NYK	vs	MIA	39	3	1	2	0	20	30	66.7	8	10	80.0	4	4	100.0	81.9	2	1	3	2	+27
5	Vince Carter V. Carter	51	12/23/2005	NJN	@	MIA	44	8	4	0	0	13	25	52.0	2	5	40.0	23	24	95.8	71.7	2	6	2	3	+16
6	Antawn Jamison A. Jamison	51	12/6/2000	GSW	vs	LAL	53	13	5	2	1	21	29	72.4	2	5	40.0	7	8	87.5	78.4	5	8	4	2	+3
7	Stephon Marbury S. Marbury	50	2/13/2001	NJN	vs	LAL	47	3	12	0	0	17	29	58.6	4	8	50.0	12	16	75.0	69.4	2	1	5	4	-5
8	Kobe Bryant K. Bryant	49	3/1/2009	LAL	@	PHX	39	11	2	1	1	18	38	47.4	3	9	33.3	10	10	100.0	57.8	4	7	1	5	-11
9	Devin Harris D. Harris	47	11/30/2008	NJN	@	PHX	41	7	8	1	0	14	25	56.0	2	3	66.7	17	17	100.0	72.4	1	6	4	2	+10
10	LeBron James L. James	47	3/12/2006	CLE	@	MIA	45	7	4	0	1	11	27	40.7	1	6	16.7	24	28	85.7	59.8	2	5	5	2	-7
11	Gilbert Arenas G. Arenas	47	12/30/2005	WAS	vs	MIA	42	7	8	0	0	15	29	51.7	4	9	44.4	13	14	92.9	66.8	3	4	3	6	-9
12	Jerry Stackhouse J. Stackhouse	46	3/15/2001	DET	vs	LAL	49	4	4	0	0	13	30	43.3	3	8	37.5	17	19	89.5	60.0	0	4	8	4	-6
13	Allen Iverson A. Iverson	45	1/24/2005	PHI	vs	MIA	44	2	10	4	0	13	30	43.3	1	3	33.3	18	19	94.7	58.7	0	2	1	1	+11
14	Mo Williams M. Williams	44	2/11/2009	CLE	vs	PHX	40	2	7	3	1	18	26	69.2	7	9	77.8	1	3	33.3	80.5	2	0	4	1	+15
15	Jason Richardson J. Richardson	44	3/10/2006	GSW	@	MIA	39	6	3	0	0	17	26	65.4	6	7	85.7	4	10	40.0	72.4	1	5	3	1	+3
16	Steve Francis S. Francis	44	1/17/2003	HOU	vs	LAL	49	6	11	2	0	12	21	57.1	6	8	75.0	14	17	82.4	77.2	0	6	7	3	+2
17	Dwyane Wade D. Wade	43	11/28/2008	MIA	@	PHX	39	3	6	1	1	15	24	62.5	2	3	66.7	11	12	91.7	73.4	0	3	2	3	+13
18	Vince Carter V. Carter	43	4/2/2006	NJN	vs	MIA	41	3	6	2	1	16	27	59.3	6	9	66.7	5	6	83.3	72.5	0	3	1	0	+22
19	Kobe Bryant K. Bryant	42	12/25/2004	LAL	vs	MIA	50	3	6	1	0	12	30	40.0	5	13	38.5	13	13	100.0	58.8	0	3	9	4	0
20	Paul Pierce P. Pierce	42	3/13/2001	BOS	@	LAL	38	6	2	4	1	13	19	68.4	3	7	42.9	13	21	61.9	74.4	1	5	3	4	-19
21	Glenn Robinson G. Robinson	42	12/18/1996	MIL	vs	LAL	46	6	2	0	1	19	30	63.3	2	3	66.7	2	2	100.0	68.0	3	3	1	3	-10
22	Kobe Bryant K. Bryant	41	1/30/2011	LAL	vs	BOS	38	3	0	0	0	16	29	55.2	3	5	60.0	6	7	85.7	63.9	0	3	2	5	-9
23	Kobe Bryant K. Bryant	41	2/20/2008	LAL	@	PHX	46	5	3	2	2	16	25	64.0	1	2	50.0	8	10	80.0	69.7	1	4	5	3	+6
24	LeBron James L. James	41	12/17/2005	CLE	vs	MIA	46	5	10	1	0	12	19	63.2	2	4	50.0	15	16	93.8	78.7	0	5	4	3	+9
25	Dirk Nowitzki D. Nowitzki	41	11/11/2004	DAL	@	MIA	42	10	4	0	2	12	24	50.0	4	7	57.1	13	13	100.0	69.0	1	9	2	2	+30