DeMar DeRozan has put up the most career points versus LeBron James, with 944 points.

who has scored the most points against lebron james

NAME	PTS	GP	MPG	PPG	RPG	APG	SPG	BPG	TPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	MIN	REB	AST	STL	BLK	TOV	PF	+/-
DeMar DeRozan	944	43	35.9	22.0	4.4	4.8	1.1	0.4	1.7	8.1	16.7	48.5	0.5	1.9	28.8	5.2	6.2	84.3	1,544	189	205	48	16	73	101	-189
Dwyane Wade	788	31	35.6	25.4	4.9	5.9	2.2	0.9	3.7	9.1	19.5	46.4	0.7	2.1	31.8	6.6	8.6	76.8	1,102	153	184	69	28	116	59	+79
Paul Pierce	786	39	36.4	20.2	5.6	3.9	1.0	0.4	2.8	6.5	15.1	42.9	1.5	4.3	35.7	5.6	6.6	85.3	1,419	219	151	39	16	108	132	+39
Carmelo Anthony	765	36	35.8	21.3	6.3	2.8	0.9	0.7	2.6	7.7	18.4	42.0	1.4	4.1	34.9	4.4	5.6	78.1	1,287	225	100	34	24	95	123	-110
Kevin Durant	746	26	38.5	28.7	6.8	4.1	1.3	1.2	3.4	9.8	20.0	48.8	2.3	5.7	41.2	6.8	7.8	86.8	1,000	178	107	33	31	89	62	-32
James Harden	725	30	36.5	24.2	6.2	7.6	1.5	0.6	4.1	7.2	15.9	45.1	2.4	7.3	33.0	7.4	8.8	84.5	1,096	186	229	46	18	123	86	+18
Joe Johnson	693	41	36.0	16.9	3.6	3.8	0.6	0.2	2.5	6.4	14.6	44.0	1.4	4.2	32.7	2.7	3.5	76.2	1,476	147	154	26	8	102	73	-105
Vince Carter	689	38	31.1	18.1	4.7	3.3	1.0	0.6	1.9	6.3	14.0	45.2	1.4	4.1	35.7	4.1	5.1	80.2	1,181	178	125	38	24	71	98	-71
Paul George	679	31	37.6	21.9	6.4	4.1	1.6	0.4	3.1	7.5	16.4	46.1	2.9	7.2	39.9	3.9	4.7	83.6	1,165	198	128	50	11	96	99	+6
Dwight Howard	670	41	35.0	16.3	12.5	1.6	0.8	1.7	2.2	6.1	11.0	55.7	0.0	0.0	0.0	4.1	7.8	53.3	1,436	513	67	32	70	91	134	-4
Jamal Crawford	598	35	31.4	17.1	2.5	3.5	1.0	0.2	2.3	6.4	14.3	44.6	1.9	5.6	34.0	2.4	3.0	81.7	1,099	86	122	34	6	82	57	-218
Damian Lillard	571	20	37.4	28.6	4.6	6.8	0.7	0.4	2.8	8.8	19.2	45.8	3.4	9.3	36.8	7.6	8.4	89.9	748	91	136	14	7	55	33	-87
Luol Deng	570	39	36.0	14.6	5.5	2.5	0.8	0.6	1.9	5.7	12.5	45.4	1.0	2.5	41.7	2.2	2.9	74.8	1,406	216	98	33	24	74	80	-42
Giannis Antetokounmpo	566	23	34.9	24.6	9.0	4.7	1.0	1.1	2.9	9.1	15.7	57.7	0.9	2.4	35.7	5.6	7.1	78.0	804	208	108	22	26	66	81	-89
Andre Iguodala	550	39	35.3	14.1	5.4	3.7	1.3	0.4	1.9	5.2	10.3	50.3	1.0	2.8	35.8	2.8	3.7	74.7	1,378	209	143	52	17	73	88	-62
LaMarcus Aldridge	548	28	34.1	19.6	7.0	2.1	0.8	0.6	1.4	7.7	15.0	51.3	0.2	0.6	27.8	4.0	5.0	79.9	955	196	58	22	18	40	66	-21
Stephen Curry	546	23	35.5	23.7	4.3	6.5	1.9	0.2	3.0	8.1	17.3	46.7	3.4	8.4	40.9	4.1	4.5	91.3	816	99	150	44	4	68	57	+75
Paul Millsap	545	36	29.3	15.1	7.1	2.0	1.1	0.7	1.7	5.6	11.3	49.8	0.7	1.9	38.8	3.2	4.0	79.9	1,055	257	72	40	26	61	117	+38
Kobe Bryant	542	22	36.9	24.6	5.0	5.2	1.1	0.2	3.2	8.7	20.4	42.8	1.4	4.1	34.1	5.8	6.8	84.7	811	111	115	24	5	70	51	-69
Rudy Gay	541	34	31.6	15.9	5.8	2.0	1.4	0.9	2.1	6.3	13.9	44.9	1.3	3.8	33.3	2.1	2.9	73.5	1,074	198	68	48	29	70	97	-188
Al Horford	537	43	32.2	12.5	7.7	2.8	0.8	1.0	1.5	5.1	9.9	51.3	0.4	1.6	26.5	1.9	2.4	79.4	1,383	330	122	34	41	64	92	-230
Russell Westbrook	534	25	34.7	21.4	6.4	7.5	2.0	0.2	3.6	7.5	18.7	40.0	0.9	2.8	31.0	5.5	7.0	79.3	867	160	188	51	6	90	80	-57
Richard Hamilton	534	32	33.4	16.7	2.8	3.5	0.8	0.2	2.3	6.1	13.6	45.0	0.6	1.7	33.3	3.9	4.5	86.7	1,070	90	113	24	5	72	75	+27
Lou Williams	531	37	26.8	14.4	2.1	3.8	0.9	0.2	1.6	4.7	11.0	42.9	1.3	3.7	35.8	3.6	4.3	82.5	991	78	141	33	6	60	41	-33
Kyle Lowry	530	33	32.0	16.1	3.8	6.3	1.3	0.2	1.8	5.1	11.7	43.4	2.0	5.2	37.6	4.0	4.7	85.1	1,056	125	209	43	6	59	98	-37