Dwyane Wade averaged 23.9 points, 6.1 assists and 4.3 rebounds in 16 games versus Paul Pierce between the 2002-03 and 2009-10 seasons.
| NAME | DATE | TM | OPP | MIN | PTS | REB | AST | STL | BLK | FGM | FGA | FG% | 3PM | 3PA | 3P% | FTM | FTA | FT% | TS% | OREB | DREB | TOV | PF | +/- | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | D. Wade | 10/29/2003 |  MIA | @ |  BOS | 34 | 5 | 2 | 4 | 1 | 0 | 2 | 12 | 16.7 | 1 | 2 | 50.0 | 0 | 0 | 20.8 | 1 | 1 | 0 | 5 | -17 | |
| 2 | | D. Wade | 4/7/2004 | MIA | vs | BOS | 40 | 16 | 8 | 4 | 0 | 0 | 5 | 12 | 41.7 | 0 | 0 | 6 | 8 | 75.0 | 51.5 | 0 | 8 | 6 | 3 | +8 | |
| 3 | | D. Wade | 11/28/2004 | MIA | vs | BOS | 39 | 25 | 5 | 9 | 2 | 1 | 7 | 18 | 38.9 | 0 | 0 | 11 | 12 | 91.7 | 53.7 | 2 | 3 | 2 | 4 | +10 | |
| 4 | | D. Wade | 12/21/2004 | MIA | vs | BOS | 41 | 33 | 4 | 11 | 4 | 2 | 11 | 20 | 55.0 | 0 | 0 | 11 | 13 | 84.6 | 64.2 | 2 | 2 | 7 | 2 | +7 | |
| 5 | | D. Wade | 4/15/2005 | MIA | @ | BOS | 44 | 17 | 3 | 2 | 0 | 0 | 6 | 17 | 35.3 | 0 | 1 | 0.0 | 5 | 5 | 100.0 | 44.3 | 1 | 2 | 1 | 3 | +5 |
| 6 | | D. Wade | 2/6/2006 | MIA | vs | BOS | 39 | 34 | 8 | 8 | 2 | 1 | 10 | 17 | 58.8 | 1 | 1 | 100.0 | 13 | 15 | 86.7 | 72.0 | 3 | 5 | 2 | 4 | +19 |
| 7 | | D. Wade | 3/1/2006 | MIA | @ | BOS | 40 | 24 | 5 | 8 | 2 | 0 | 7 | 15 | 46.7 | 0 | 0 | 10 | 16 | 62.5 | 54.4 | 2 | 3 | 5 | 3 | +3 | |
| 8 | | D. Wade | 3/16/2006 | MIA | vs | BOS | 40 | 30 | 2 | 6 | 3 | 1 | 12 | 20 | 60.0 | 0 | 2 | 0.0 | 6 | 11 | 54.5 | 60.4 | 1 | 1 | 1 | 2 | +2 |
| 9 | | D. Wade | 11/16/2007 | MIA | @ | BOS | 38 | 23 | 1 | 6 | 1 | 0 | 8 | 15 | 53.3 | 0 | 1 | 0.0 | 7 | 12 | 58.3 | 56.7 | 0 | 1 | 3 | 0 | -4 |
| 10 | | D. Wade | 11/30/2007 | MIA | vs | BOS | 42 | 10 | 5 | 1 | 3 | 2 | 2 | 11 | 18.2 | 0 | 2 | 0.0 | 6 | 11 | 54.5 | 31.6 | 1 | 4 | 6 | 4 | -5 |
| 11 | | D. Wade | 1/29/2008 | MIA | vs | BOS | 28 | 7 | 4 | 6 | 0 | 0 | 1 | 9 | 11.1 | 0 | 1 | 0.0 | 5 | 5 | 100.0 | 31.3 | 1 | 3 | 4 | 2 | -25 |
| 12 | | D. Wade | 1/21/2009 | MIA | vs | BOS | 43 | 25 | 4 | 4 | 2 | 0 | 9 | 17 | 52.9 | 2 | 5 | 40.0 | 5 | 7 | 71.4 | 62.3 | 1 | 3 | 3 | 4 | -17 |
| 13 | | D. Wade | 3/11/2009 | MIA | vs | BOS | 37 | 32 | 4 | 7 | 4 | 0 | 9 | 20 | 45.0 | 1 | 4 | 25.0 | 13 | 16 | 81.3 | 59.2 | 2 | 2 | 1 | 0 | +13 |
| 14 | | D. Wade | 4/10/2009 | MIA | @ | BOS | 40 | 31 | 3 | 9 | 0 | 1 | 11 | 20 | 55.0 | 2 | 4 | 50.0 | 7 | 13 | 53.8 | 60.3 | 0 | 3 | 1 | 4 | -6 |
| 15 | | D. Wade | 11/29/2009 | MIA | vs | BOS | 37 | 27 | 5 | 6 | 2 | 1 | 11 | 23 | 47.8 | 0 | 3 | 0.0 | 5 | 8 | 62.5 | 50.9 | 1 | 4 | 3 | 1 | -14 |
| 16 | | D. Wade | 1/6/2010 | MIA | vs | BOS | 43 | 44 | 5 | 7 | 3 | 1 | 15 | 34 | 44.1 | 3 | 7 | 42.9 | 11 | 16 | 68.8 | 53.6 | 5 | 0 | 2 | 5 | -11 |
| Average | 39.1 | 23.9 | 4.3 | 6.1 | 1.8 | 0.6 | 7.9 | 17.5 | 45.0 | 0.6 | 2.1 | 30.3 | 7.6 | 10.5 | 72.0 | 54.1 | 1.4 | 2.8 | 2.9 | 2.9 | -2.0 | ||||||
| Total | 625 | 383 | 68 | 98 | 29 | 10 | 126 | 280 | 45.0 | 10 | 33 | 30.3 | 121 | 168 | 72.0 | 54.1 | 23 | 45 | 47 | 46 | -32 |
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