Karl-Anthony Towns has averaged his most career points per game against the Pacers, with 27.3 per game.

karl-anthony towns highest career ppg by opponent

OPP	PPG	GP	MPG	RPG	APG	SPG	BPG	TPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	MIN	PTS	REB	AST	STL	BLK	TOV	PF	+/-
Pacers	27.3	15	33.9	10.9	2.9	0.9	1.3	3.4	9.9	17.7	56.0	1.6	4.1	38.7	5.9	6.7	87.1	508	410	163	44	14	19	51	52	+4
Hornets	27.3	16	33.7	11.1	3.5	0.9	1.6	2.8	9.7	19.4	49.8	2.4	6.1	40.2	5.4	6.7	81.3	539	436	178	56	14	25	44	53	+12
Wizards	26.9	14	36.0	10.6	3.5	0.7	1.1	2.9	10.3	19.3	53.3	1.9	4.6	40.0	4.5	5.1	87.5	504	377	149	49	10	15	40	45	-5
Rockets	26.2	25	33.5	12.8	3.6	1.0	1.4	2.9	10.0	18.3	54.6	1.7	4.0	42.4	4.5	5.2	86.2	837	654	319	91	24	36	72	84	+109
Nets	25.4	14	34.8	11.5	2.9	0.9	1.9	2.9	9.9	17.9	55.6	1.9	4.4	42.6	3.6	4.4	82.3	488	355	161	40	13	26	41	44	+74
Knicks	25.2	12	36.6	11.2	3.8	0.8	1.8	2.6	8.8	16.8	52.5	1.8	4.1	44.9	5.7	6.4	88.3	439	302	134	46	10	21	31	44	+6
Bulls	24.8	13	35.2	11.8	3.8	0.6	1.3	2.2	9.5	17.9	53.2	1.6	4.8	33.3	4.2	4.9	84.4	458	323	153	49	8	17	29	48	+145
Nuggets	24.0	23	34.8	11.0	3.7	1.0	1.5	2.4	8.9	16.7	53.1	1.5	3.8	39.8	4.7	5.5	85.7	800	551	252	86	22	34	56	81	+46
Pelicans	23.8	26	33.1	11.0	2.8	0.8	1.4	3.0	8.7	16.9	51.5	2.1	4.6	45.8	4.3	5.2	83.6	860	619	286	72	21	36	77	104	+59
Suns	23.3	27	34.4	10.9	3.1	0.8	1.0	2.9	8.3	16.3	51.3	1.9	4.8	40.0	4.7	5.4	86.3	930	628	293	85	22	28	77	93	-24
Kings	23.2	25	33.9	11.2	3.8	0.6	1.6	2.8	8.6	15.5	55.2	1.8	3.9	44.9	4.3	5.2	83.1	848	580	281	95	14	41	71	83	+97
Jazz	23.2	27	33.9	10.8	2.8	0.9	1.1	2.8	8.2	15.7	52.5	2.1	4.7	44.4	4.7	5.5	84.6	915	626	292	75	24	29	76	89	+34
Hawks	23.1	15	34.3	12.1	4.1	0.7	1.4	2.7	8.1	15.3	52.6	2.0	4.5	44.8	5.0	6.4	78.1	515	347	181	62	10	21	41	53	+16
Warriors	23.1	24	34.8	11.4	3.2	0.9	0.6	2.6	8.8	17.7	50.0	1.8	4.9	36.4	3.7	5.2	70.4	836	555	273	76	21	15	62	69	-80
Mavericks	22.8	25	34.2	11.1	3.5	0.8	1.2	2.8	8.6	15.4	55.7	1.6	3.9	41.8	4.0	4.8	83.3	856	569	277	87	20	31	71	82	+103
Cavaliers	22.6	11	34.8	9.3	2.8	0.6	1.5	2.4	9.2	15.3	60.1	1.6	3.7	43.9	2.6	3.1	85.3	383	249	102	31	7	16	26	32	-17
Thunder	22.5	29	32.9	10.1	2.7	0.8	1.2	2.8	7.9	15.3	51.8	1.4	3.8	37.6	5.2	5.8	89.9	954	653	293	77	23	34	82	95	+53
Celtics	22.3	13	37.0	13.0	3.7	0.5	0.9	2.7	8.4	16.6	50.5	1.2	4.2	29.1	4.3	5.1	84.8	481	290	169	48	6	12	35	47	-97
Lakers	22.0	25	34.4	10.8	3.4	0.9	1.6	2.6	8.1	15.9	51.0	1.5	4.5	33.9	4.3	5.0	85.6	859	551	271	84	22	40	65	90	+201
Spurs	22.0	27	34.2	11.2	3.1	0.6	0.9	3.0	8.0	15.7	50.8	1.8	4.2	43.0	4.2	5.0	83.8	923	593	302	84	17	23	81	93	-28
Magic	21.9	14	35.3	10.3	3.1	0.9	1.6	2.3	8.1	15.6	51.8	1.7	4.1	42.1	4.1	4.9	82.6	494	307	144	43	13	22	32	40	+68
Bucks	21.8	13	33.0	9.4	3.5	0.7	1.1	2.8	8.5	15.8	53.7	2.2	4.9	45.3	2.6	3.4	77.3	429	283	122	46	9	14	36	37	+23
Pistons	21.7	14	33.7	9.2	3.1	0.6	1.3	2.6	8.2	15.1	54.2	1.8	4.4	40.3	3.5	4.1	86.0	472	304	129	44	8	18	37	44	-23
Clippers	21.4	25	33.0	10.2	3.1	1.2	0.8	2.6	8.0	15.0	53.3	1.7	4.6	36.2	3.7	4.7	79.5	825	535	256	78	29	20	64	84	+9
Trail Blazers	20.8	27	32.4	10.1	2.4	0.6	1.3	2.4	7.3	14.1	51.6	1.2	3.0	39.0	5.0	6.0	83.9	876	561	273	66	17	36	64	84	+100