Kobe Bryant has the highest career plus/minus for the Lakers when playing 10.0+ minutes per game, at +4153.

	NAME	+/-	MPG	GP	PPG	RPG	APG	SPG	BPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TPG	MIN	PTS	REB	AST	STL	BLK	TOV	PF
1	Kobe Bryant K. Bryant	+4153	36.1	1,346	25.0	5.2	4.7	1.4	0.5	8.7	19.5	44.7	1.4	4.1	32.9	6.2	7.4	83.7	55.0	1.1	4.1	3.0	48,637	33,643	7,047	6,306	1,944	640	4,010	3,353
2	Derek Fisher D. Fisher	+3696	25.4	915	7.9	2.1	2.9	1.1	0.1	2.8	7.0	40.2	0.9	2.5	37.5	1.4	1.7	79.9	51.1	0.3	1.7	1.1	23,211	7,223	1,892	2,685	968	73	974	1,793
3	Shaquille O'Neal S. O'Neal	+3677	37.6	514	27.0	11.8	3.1	0.6	2.5	10.6	18.5	57.5	0.0	0.0	0.0	5.8	10.8	53.3	58.1	3.8	8.0	2.8	19,329	13,895	6,090	1,593	317	1,278	1,446	1,692
4	Lamar Odom L. Odom	+2073	35.1	519	13.7	9.5	3.7	0.9	0.9	5.2	10.6	49.1	0.7	2.1	33.0	2.5	3.7	68.3	55.8	2.2	7.2	2.2	18,204	7,092	4,906	1,944	444	451	1,120	1,533
5	Robert Horry R. Horry	+1745	25.4	448	6.3	5.5	2.2	1.1	1.0	2.3	5.4	42.1	0.6	1.9	32.5	1.2	1.6	74.4	52.1	1.8	3.7	1.2	11,367	2,842	2,462	986	497	446	526	1,267
6	Pau Gasol P. Gasol	+1571	35.7	429	17.7	9.9	3.5	0.6	1.4	7.0	13.3	52.2	0.0	0.2	26.3	3.8	4.8	78.0	57.4	2.9	7.0	2.0	15,326	7,610	4,240	1,508	239	607	873	925
7	Rick Fox R. Fox	+1482	26.2	486	8.7	3.7	2.9	0.9	0.3	3.3	7.5	43.6	1.0	2.9	34.5	1.1	1.4	76.7	53.0	0.9	2.8	1.6	12,733	4,207	1,784	1,399	415	152	781	1,409
8	LeBron James L. James	+1106	35.2	419	26.6	7.9	8.1	1.1	0.6	10.0	19.6	51.3	2.3	6.3	36.0	4.3	5.9	72.9	60.1	1.0	6.9	3.6	14,743	11,146	3,316	3,376	480	262	1,505	668
9	Eddie Jones E. Jones	+986	36.8	180	16.6	3.9	3.2	2.1	0.7	5.9	12.9	45.6	1.8	4.6	38.4	3.2	4.0	78.7	56.9	1.1	2.8	1.9	6,632	2,994	704	577	384	128	336	432
10	Andrew Bynum A. Bynum	+909	26.0	392	11.7	7.8	1.2	0.3	1.6	4.7	8.2	56.6	0.0	0.0	11.1	2.4	3.5	68.7	60.0	2.4	5.4	1.6	10,174	4,597	3,076	461	127	628	610	997
11	Metta Sandiford-Artest M. Sandiford-Artest	+900	28.0	358	8.9	3.6	2.0	1.3	0.4	3.2	8.2	39.4	1.2	3.5	33.5	1.3	1.9	68.5	49.5	1.1	2.5	1.1	10,015	3,197	1,297	699	453	139	400	766
12	Anthony Davis A. Davis	+641	34.4	312	24.8	11.0	3.2	1.2	2.2	9.2	17.3	53.2	0.6	2.1	28.2	5.8	7.3	79.4	60.4	2.8	8.2	2.2	10,741	7,739	3,419	987	389	674	684	718
13	Devean George D. George	+586	18.9	429	6.0	3.3	1.0	0.7	0.4	2.2	5.7	39.2	0.7	1.9	34.0	0.9	1.2	71.8	48.2	1.0	2.4	0.8	8,109	2,572	1,433	428	307	173	340	891
14	Nick Van Exel N. Van Exel	+579	34.9	143	14.6	2.9	7.8	1.0	0.1	5.2	12.7	40.9	2.1	5.5	38.3	2.1	2.6	80.9	52.7	0.5	2.4	2.2	4,990	2,087	420	1,114	139	16	316	230
15	Glen Rice G. Rice	+458	32.9	107	16.3	4.0	2.3	0.6	0.2	5.5	12.9	43.0	1.3	3.4	37.6	4.0	4.5	87.0	54.8	0.6	3.4	1.5	3,515	1,744	426	247	64	18	159	246
16	Luke Walton L. Walton	+435	17.3	493	4.9	2.9	2.3	0.5	0.2	1.9	4.5	43.3	0.3	1.0	32.6	0.7	1.0	72.4	50.0	0.9	2.0	1.0	8,529	2,434	1,408	1,121	268	88	512	680
17	Austin Reaves A. Reaves	+422	30.1	280	14.5	3.8	4.3	0.7	0.3	4.8	9.9	48.1	1.8	4.8	37.0	3.1	3.6	86.3	62.6	0.7	3.1	1.8	8,440	4,052	1,067	1,196	209	86	490	499
18	Alex Caruso A. Caruso	+413	18.9	184	5.9	2.3	2.4	1.0	0.3	2.1	4.8	42.9	0.7	1.9	37.7	1.0	1.4	72.0	54.0	0.5	1.9	1.2	3,484	1,082	425	436	181	52	213	312
19	Ron Harper R. Harper	+409	25.0	127	6.8	4.0	3.0	1.0	0.5	2.7	6.3	42.3	0.4	1.4	29.2	1.1	1.5	68.7	48.7	1.1	2.8	1.5	3,181	864	503	383	124	64	194	234
20	Vladimir Radmanovic V. Radmanovic	+338	19.5	166	7.1	3.1	1.4	0.6	0.2	2.6	5.8	44.2	1.2	2.9	40.0	0.8	1.0	77.6	56.6	0.8	2.3	1.1	3,240	1,177	512	227	99	37	189	323
21	Gary Payton G. Payton	+329	34.5	82	14.6	4.2	5.5	1.2	0.2	5.9	12.5	47.1	0.7	2.0	33.3	2.2	3.1	71.4	52.8	0.9	3.3	1.8	2,825	1,199	342	449	96	19	151	169
22	A.C. Green	+328	23.5	82	5.0	5.9	1.0	0.6	0.2	2.1	4.7	44.7	0.0	0.0	25.0	0.8	1.2	69.5	48.2	2.0	4.0	0.6	1,929	413	486	80	53	18	53	127
23	Rui Hachimura R. Hachimura	+322	27.7	160	12.6	4.7	1.2	0.6	0.4	4.9	9.5	51.7	1.4	3.4	40.2	1.4	1.9	74.7	61.2	1.1	3.6	0.7	4,433	2,015	744	187	94	65	112	239
24	Horace Grant H. Grant	+318	26.5	132	6.7	5.9	1.5	0.6	0.6	2.7	6.0	44.8	0.0	0.0	0.0	1.3	1.7	76.2	49.4	2.3	3.6	0.6	3,496	880	778	192	75	82	77	251
25	Jordan Farmar J. Farmar	+278	18.6	342	7.3	1.9	2.5	0.8	0.1	2.8	6.5	42.9	1.1	2.9	37.2	0.7	1.0	67.1	52.7	0.3	1.6	1.3	6,358	2,492	654	843	268	41	435	461