LeBron James averaged 29.8 points, 7.1 assists and 5.2 rebounds in 13 games versus Shaquille O'Neal between the 2003-04 and 2007-08 seasons.
| NAME | DATE | TM | OPP | MIN | PTS | REB | AST | STL | BLK | FGM | FGA | FG% | 3PM | 3PA | 3P% | FTM | FTA | FT% | TS% | OREB | DREB | TOV | PF | +/- | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | L. James | 2/4/2004 |  CLE | vs |  LAL | 43 | 32 | 4 | 4 | 0 | 0 | 12 | 26 | 46.2 | 4 | 4 | 100.0 | 4 | 5 | 80.0 | 56.7 | 0 | 4 | 0 | 0 | -2 |
| 2 | | L. James | 11/4/2004 | CLE | @ |  MIA | 43 | 21 | 6 | 8 | 1 | 0 | 9 | 22 | 40.9 | 2 | 3 | 66.7 | 1 | 1 | 100.0 | 46.8 | 3 | 3 | 1 | 0 | -8 |
| 3 | | L. James | 2/3/2005 | CLE | @ | MIA | 46 | 31 | 2 | 10 | 3 | 0 | 11 | 23 | 47.8 | 1 | 3 | 33.3 | 8 | 12 | 66.7 | 54.8 | 2 | 0 | 2 | 2 | -8 |
| 4 | | L. James | 3/6/2005 | CLE | vs | MIA | 41 | 23 | 4 | 5 | 2 | 0 | 9 | 19 | 47.4 | 0 | 1 | 0.0 | 5 | 7 | 71.4 | 52.1 | 0 | 4 | 1 | 1 | -17 |
| 5 | | L. James | 12/17/2005 | CLE | vs | MIA | 46 | 41 | 5 | 10 | 1 | 0 | 12 | 19 | 63.2 | 2 | 4 | 50.0 | 15 | 16 | 93.8 | 78.7 | 0 | 5 | 4 | 3 | +9 |
| 6 | | L. James | 2/2/2006 | CLE | @ | MIA | 39 | 29 | 5 | 7 | 1 | 0 | 12 | 29 | 41.4 | 2 | 5 | 40.0 | 3 | 3 | 100.0 | 47.8 | 1 | 4 | 1 | 0 | -15 |
| 7 | | L. James | 3/12/2006 | CLE | @ | MIA | 45 | 47 | 7 | 4 | 0 | 1 | 11 | 27 | 40.7 | 1 | 6 | 16.7 | 24 | 28 | 85.7 | 59.8 | 2 | 5 | 5 | 2 | -7 |
| 8 | | L. James | 2/1/2007 | CLE | @ | MIA | 36 | 17 | 6 | 9 | 1 | 0 | 6 | 18 | 33.3 | 2 | 7 | 28.6 | 3 | 8 | 37.5 | 39.5 | 1 | 5 | 2 | 4 | -12 |
| 9 | | L. James | 2/9/2007 | CLE | vs | MIA | 41 | 29 | 7 | 6 | 0 | 0 | 12 | 22 | 54.5 | 1 | 4 | 25.0 | 4 | 8 | 50.0 | 56.8 | 1 | 6 | 2 | 1 | +22 |
| 10 | | L. James | 2/25/2007 | CLE | @ | MIA | 42 | 29 | 3 | 7 | 0 | 1 | 10 | 22 | 45.5 | 2 | 5 | 40.0 | 7 | 12 | 58.3 | 53.2 | 0 | 3 | 2 | 2 | +6 |
| 11 | | L. James | 4/5/2007 | CLE | vs | MIA | 49 | 35 | 9 | 5 | 0 | 0 | 11 | 21 | 52.4 | 2 | 5 | 40.0 | 11 | 13 | 84.6 | 65.5 | 2 | 7 | 4 | 4 | +3 |
| 12 | | L. James | 12/25/2007 | CLE | vs | MIA | 39 | 25 | 6 | 12 | 1 | 1 | 9 | 19 | 47.4 | 0 | 3 | 0.0 | 7 | 11 | 63.6 | 52.4 | 0 | 6 | 2 | 3 | +18 |
| 13 | | L. James | 1/21/2008 | CLE | @ | MIA | 40 | 28 | 3 | 5 | 4 | 1 | 11 | 26 | 42.3 | 1 | 4 | 25.0 | 5 | 5 | 100.0 | 49.6 | 1 | 2 | 5 | 4 | +12 |
| Average | 42.2 | 29.8 | 5.2 | 7.1 | 1.1 | 0.3 | 10.4 | 22.5 | 46.1 | 1.5 | 4.2 | 37.0 | 7.5 | 9.9 | 75.2 | 55.3 | 1.0 | 4.2 | 2.4 | 2.0 | 0.1 | ||||||
| Total | 549 | 387 | 67 | 92 | 14 | 4 | 135 | 293 | 46.1 | 20 | 54 | 37.0 | 97 | 129 | 75.2 | 55.3 | 13 | 54 | 31 | 26 | +1 |
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