Between the 2004-05 and 2006-07 seasons, Shaquille O'Neal dropped his most points in a game 2 in Game 2 of the 2006 First Round versus the Bulls, with 22 points.
| NAME | PTS | DATE | TM | OPP | MIN | REB | AST | STL | BLK | FGM | FGA | FG% | 3PM | 3PA | 3P% | FTM | FTA | FT% | TS% | OREB | DREB | TOV | PF | +/- | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | S. O'Neal | 22 | 4/24/2006 |  MIA | vs |  CHI | 35 | 7 | 3 | 0 | 3 | 8 | 14 | 57.1 | 0 | 0 | 6 | 7 | 85.7 | 64.4 | 2 | 5 | 2 | 4 | +11 | |
| 2 | | S. O'Neal | 21 | 5/25/2006 | MIA | @ |  DET | 40 | 12 | 0 | 0 | 4 | 9 | 16 | 56.3 | 0 | 0 | 3 | 5 | 60.0 | 57.7 | 4 | 8 | 4 | 3 | -10 | |
| 3 | | S. O'Neal | 21 | 5/10/2006 | MIA | vs |  NJN | 29 | 6 | 3 | 0 | 0 | 9 | 17 | 52.9 | 0 | 0 | 3 | 10 | 30.0 | 49.1 | 4 | 2 | 0 | 2 | +22 | |
| 4 | | S. O'Neal | 17 | 4/24/2007 | MIA | @ | CHI | 31 | 8 | 1 | 0 | 1 | 6 | 14 | 42.9 | 0 | 0 | 5 | 5 | 100.0 | 52.5 | 5 | 3 | 7 | 3 | -19 | |
| 5 | | S. O'Neal | 17 | 5/25/2005 | MIA | vs |  DET | 33 | 10 | 1 | 0 | 2 | 8 | 15 | 53.3 | 0 | 0 | 1 | 5 | 20.0 | 49.4 | 2 | 8 | 2 | 4 | +7 | |
| 6 | | S. O'Neal | 16 | 5/10/2005 | MIA | vs |  WAS | 37 | 7 | 2 | 0 | 2 | 6 | 11 | 54.5 | 0 | 0 | 4 | 8 | 50.0 | 55.1 | 1 | 6 | 3 | 4 | -4 | |
| 7 | | S. O'Neal | 14 | 4/26/2005 | MIA | vs | NJN | 26 | 10 | 4 | 0 | 1 | 4 | 9 | 44.4 | 0 | 0 | 6 | 11 | 54.5 | 50.6 | 1 | 9 | 2 | 4 | +10 | |
| 8 | | S. O'Neal | 5 | 6/11/2006 | MIA | @ |  DAL | 28 | 6 | 2 | 0 | 0 | 2 | 5 | 40.0 | 0 | 0 | 1 | 7 | 14.3 | 30.9 | 1 | 5 | 2 | 1 | -27 |
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