Matt Ryan had his most passing yards in a game versus the Panthers on October 2, 2016, with 503 yards.

Interpreted as:

Matt Ryan most passing yards in a regular-season game

	NAME	YDS	DATE	TM		OPP	CMP	ATT	PCT	AVG	TD	INT	RTG	TD%	INT%	SCK	SCKY
1	Matt Ryan M. Ryan	503	10/2/2016	ATL	vs	CAR	28	37	75.7	13.6	4	1	142.0	10.8	2.7	3	22
2	Matt Ryan M. Ryan	450	9/13/2020	ATL	vs	SEA	37	54	68.5	8.3	2	1	98.5	3.7	1.9	2	16
3	Matt Ryan M. Ryan	448	9/7/2014	ATL	vs	NO	31	43	72.1	10.4	3	0	128.8	7.0	0.0	1	3
4	Matt Ryan M. Ryan	421	9/29/2013	ATL	vs	NE	34	54	63.0	7.8	2	1	91.7	3.7	1.9	2	22
5	Matt Ryan M. Ryan	419	9/30/2018	ATL	vs	CIN	29	39	74.4	10.7	3	0	134.5	7.7	0.0	3	16
6	Matt Ryan M. Ryan	411	11/11/2012	ATL	@	NO	34	52	65.4	7.9	3	1	100.7	5.8	1.9	1	3
7	Matt Ryan M. Ryan	397	9/29/2019	ATL	vs	TEN	35	53	66.0	7.5	0	0	88.3	0.0	0.0	5	33
8	Matt Ryan M. Ryan	397	11/1/2015	ATL	vs	TB	37	45	82.2	8.8	2	1	109.0	4.4	2.2	1	2
9	Matt Ryan M. Ryan	396	9/18/2016	ATL	@	OAK	26	34	76.5	11.6	3	1	131.5	8.8	2.9	1	7
10	Matt Ryan M. Ryan	389	10/16/2022	IND	vs	JAX	42	58	72.4	6.7	3	0	107.6	5.2	0.0	0	0
11	Matt Ryan M. Ryan	384	12/22/2019	ATL	vs	JAX	32	45	71.1	8.5	1	2	85.8	2.2	4.4	1	1
12	Matt Ryan M. Ryan	379	10/22/2018	ATL	vs	NYG	31	39	79.5	9.7	1	0	115.7	2.6	0.0	3	23
13	Matt Ryan M. Ryan	378	12/30/2018	ATL	@	TB	31	44	70.5	8.6	2	1	102.3	4.5	2.3	1	3
14	Matt Ryan M. Ryan	377	11/22/2018	ATL	@	NO	35	47	74.5	8.0	2	1	102.9	4.3	2.1	6	37
15	Matt Ryan M. Ryan	375	12/8/2014	ATL	@	GB	24	39	61.5	9.6	4	1	116.9	10.3	2.6	1	1
16	Matt Ryan M. Ryan	374	9/23/2018	ATL	vs	NO	26	35	74.3	10.7	5	0	148.1	14.3	0.0	3	15
17	Matt Ryan M. Ryan	374	9/15/2013	ATL	vs	STL	33	43	76.7	8.7	2	0	117.8	4.7	0.0	2	17
18	Matt Ryan M. Ryan	373	12/26/2011	ATL	@	NO	34	52	65.4	7.2	1	0	92.9	1.9	0.0	0	0
19	Matt Ryan M. Ryan	371	10/18/2020	ATL	@	MIN	30	40	75.0	9.3	4	0	136.6	10.0	0.0	2	8
20	Matt Ryan M. Ryan	369	9/30/2012	ATL	vs	CAR	25	40	62.5	9.2	3	1	107.2	7.5	2.5	7	64
21	Matt Ryan M. Ryan	363	9/20/2015	ATL	@	NYG	30	46	65.2	7.9	1	0	96.6	2.2	0.0	2	17
22	Matt Ryan M. Ryan	361	11/30/2014	ATL	vs	ARI	30	41	73.2	8.8	2	1	105.8	4.9	2.4	1	3
23	Matt Ryan M. Ryan	356	10/2/2022	IND	vs	TEN	27	37	73.0	9.6	2	1	109.7	5.4	2.7	3	29
24	Matt Ryan M. Ryan	356	12/20/2020	ATL	vs	TB	34	49	69.4	7.3	3	0	110.6	6.1	0.0	3	24
25	Matt Ryan M. Ryan	356	10/13/2019	ATL	@	ARI	30	36	83.3	9.9	4	0	144.9	11.1	0.0	2	15

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Results may be incomplete. StatMuse has complete game-level data for passing yards going back to the 1950 season.

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Matt Ryan had his most passing yards in a game versus the Panthers on October 2, 2016, with 503 yards.

Interpreted as:

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