8 teams are tied for the most interception touchdowns in a Week-1 game, scoring 2 touchdowns. The first three are the San Francisco 49ers on September 8, 2019, the Los Angeles Rams on September 10, 2017 and the Minnesota Vikings on September 9, 2007.
| TEAM | INT TD | DATE | TM | OPP | RESULT | TKL | AST | COMB | SCK | SCKY | INT | INT YDS | FF | FR | FR TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 2 | 9/8/2019 | @ | W 31-17 | 44 | 15 | 59 | 3.0 | 20 | 3 | 57 | 2 | 1 | 0 | ||
| 2 |  | Rams | 2 | 9/10/2017 | vs | W 46-9 | 41 | 7 | 48 | 4.0 | 29 | 2 | 68 | 2 | 1 | 0 | ||
| 3 |  | Vikings | 2 | 9/9/2007 | vs | W 24-3 | 62 | 15 | 77 | 6.0 | 30 | 2 | 68 | 1 | 0 | 0 | ||
| 4 |  | Broncos | 2 | 9/10/1989 | vs | W 34-20 | 2.0 | 8 | 2 | 52 | 2 | 0 | ||||||
| 5 |  | Cowboys | 2 | 9/9/1985 | vs | W 44-14 | 2.0 | 8 | 6 | 84 | 1 | 0 | ||||||
| 6 |  | Dolphins | 2 | 9/12/1982 | @ | W 45-28 | 4.0 | 36 | 3 | 59 | 1 | 0 | ||||||
| 7 |  | Chiefs | 2 | 9/15/1974 | vs | W 24-16 | 0.0 | 0 | 4 | 96 | 2 | 0 | ||||||
| 8 |  | Packers | 2 | 9/10/1966 | vs | W 24-3 | 1.0 | 5 | 3 | 98 | 0 | 0 | ||||||
| 9 |  | Bears | 1 | 9/8/2025 | vs | L 24-27 | 38 | 22 | 60 | 3.0 | 9 | 1 | 74 | 0 | 0 | 0 | ||
| 10 | | Bears | 1 | 9/8/2024 | vs | W 24-17 | 48 | 22 | 70 | 3.0 | 23 | 2 | 52 | 1 | 1 | 0 | ||
| 11 | | Vikings | 1 | 9/8/2024 | @ | W 28-6 | 42 | 24 | 66 | 5.0 | 20 | 2 | 10 | 0 | 0 | 0 | ||
| 12 | | Packers | 1 | 9/10/2023 | @ | W 38-20 | 51 | 26 | 77 | 4.0 | 27 | 1 | 37 | 1 | 1 | 0 | ||
| 13 |  | Eagles | 1 | 9/10/2023 | @ | W 25-20 | 46 | 32 | 78 | 2.0 | 10 | 1 | 70 | 2 | 1 | 0 | ||
| 14 | | Cowboys | 1 | 9/10/2023 | @ | W 40-0 | 44 | 21 | 65 | 7.0 | 47 | 2 | 22 | 3 | 1 | 0 | ||
| 15 |  | Lions | 1 | 9/7/2023 | @ | W 21-20 | 40 | 13 | 53 | 0.0 | 0 | 1 | 50 | 0 | 0 | 0 | ||
| 16 | | Eagles | 1 | 9/11/2022 | @ | W 38-35 | 39 | 18 | 57 | 1.0 | 10 | 1 | 27 | 0 | 0 | 0 | ||
| 17 |  | Steelers | 1 | 9/11/2022 | @ | W 23-20 | 63 | 30 | 93 | 7.0 | 39 | 4 | 31 | 2 | 1 | 0 | ||
| 18 | | 49ers | 1 | 9/12/2021 | @ | W 41-33 | 49 | 26 | 75 | 3.0 | 24 | 1 | 39 | 0 | 0 | 0 | ||
| 19 |  | Saints | 1 | 9/13/2020 | vs | W 34-23 | 45 | 13 | 58 | 3.0 | 15 | 2 | 53 | 1 | 1 | 0 | ||
| 20 |  | Titans | 1 | 9/8/2019 | @ | W 43-13 | 46 | 14 | 60 | 5.0 | 41 | 3 | 66 | 0 | 0 | 0 | ||
| 21 |  | Jets | 1 | 9/8/2019 | vs | L 16-17 | 36 | 25 | 61 | 1.0 | 12 | 2 | 21 | 1 | 2 | 0 | ||
| 22 |  | Buccaneers | 1 | 9/8/2019 | vs | L 17-31 | 42 | 15 | 57 | 1.0 | 8 | 1 | 15 | 0 | 1 | 0 | ||
| 23 | | Lions | 1 | 9/10/2018 | vs | L 17-48 | 47 | 10 | 57 | 2.0 | 18 | 1 | 37 | 1 | 1 | 0 | ||
| 24 |  | Jets | 1 | 9/10/2018 | @ | W 48-17 | 38 | 8 | 46 | 0.0 | 0 | 5 | 102 | 0 | 0 | 0 | ||
| 25 | | Rams | 1 | 9/10/2018 | @ | W 33-13 | 45 | 24 | 69 | 1.0 | 3 | 3 | 57 | 0 | 0 | 0 | ||
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NYJResults may be incomplete. StatMuse has complete team, game-level data for interception touchdowns going back to the 1940 season.
More 49ers Stats
Team Leaders 
PASS
2,167
Purdy
RUSH
1,202
McCaffrey
REC
924
McCaffrey
Team Rankings
PPG
25.7
10th
OPP PPG
21.8
13th
RUSH YDS/G
106.9
24th
PASS YDS/G
254.0
6th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
