most interceptions thrown vs 49ers

Johnny Unitas has the most career interceptions versus the 49ers, with 25 interceptions.

Interpreted as:
most interceptions thrown by a player vs 49ers
NAMEINTGPCMPATTPCTYDSAVGYDS/GTDRTGTD%INT%SCKSCKY
1Johnny Unitas
J. Unitas
25
28
397
728
54.5
5,725
7.9
204.5
40
84.3
5.5
3.4
2Tobin Rote
T. Rote
21
18
186
399
46.6
2,532
6.3
140.7
21
63.0
5.3
5.3
3Bobby Layne
B. Layne
21
16
184
389
47.3
2,496
6.4
156.0
15
58.6
3.9
5.4
4Chris Miller
C. Miller
20
14
190
385
49.4
2,443
6.3
174.5
13
59.3
3.4
5.2
27
180
5Norm Van Brocklin
N. Van Brocklin
20
18
199
370
53.8
2,730
7.4
151.7
20
73.1
5.4
5.4
6Jim Everett
J. Everett
19
18
324
604
53.6
3,880
6.4
215.6
21
72.0
3.5
3.1
25
171
7Bobby Hebert
B. Hebert
19
18
293
507
57.8
3,299
6.5
183.3
22
76.2
4.3
3.7
33
243
8Billy Wade
B. Wade
19
20
201
385
52.2
2,640
6.9
132.0
23
73.5
6.0
4.9
9Matt Hasselbeck
M. Hasselbeck
17
18
317
494
64.2
3,665
7.4
203.6
27
90.4
5.5
3.4
26
128
10Archie Manning
A. Manning
17
18
242
424
57.1
2,804
6.6
155.8
16
73.1
3.8
4.0
11Fran Tarkenton
F. Tarkenton
17
17
229
427
53.6
3,192
7.5
187.8
23
79.3
5.4
4.0
12Roman Gabriel
R. Gabriel
15
19
225
490
45.9
3,236
6.6
170.3
25
72.1
5.1
3.1
13Kurt Warner
K. Warner
14
14
307
473
64.9
3,807
8.0
271.9
24
94.3
5.1
3.0
30
209
14Steve Bartkowski
S. Bartkowski
14
18
290
492
58.9
3,416
6.9
189.8
20
81.8
4.1
2.8
15Bart Starr
B. Starr
14
26
224
364
61.5
2,908
8.0
111.8
21
89.9
5.8
3.8
16Kerry Collins
K. Collins
13
7
130
242
53.7
1,590
6.6
227.1
5
58.7
2.1
5.4
17
101
17Ed Brown
E. Brown
12
17
107
213
50.2
1,642
7.7
96.6
8
65.1
3.8
5.6
18Babe Parilli
B. Parilli
12
7
52
114
45.6
647
5.7
92.4
5
38.8
4.4
10.5
19George Blanda
G. Blanda
12
17
97
194
50.0
1,284
6.6
75.5
8
59.3
4.1
6.2
20Steve DeBerg
S. DeBerg
11
5
90
170
52.9
1,073
6.3
214.6
7
59.3
4.1
6.5
7
57
21Earl Morrall
E. Morrall
11
15
93
188
49.5
1,422
7.6
94.8
10
68.2
5.3
5.9
22Russell Wilson
R. Wilson
10
21
389
603
64.5
4,353
7.2
207.3
36
98.9
6.0
1.7
58
390
23Brett Favre
B. Favre
10
9
188
310
60.6
2,246
7.2
249.6
14
84.4
4.5
3.2
15
98
24Chris Chandler
C. Chandler
10
15
212
416
51.0
2,772
6.7
184.8
17
75.9
4.1
2.4
35
231
25Mike Tomczak
M. Tomczak
10
6
52
109
47.7
568
5.2
94.7
1
28.4
0.9
9.2
5
26
StatMuse has game-level data for intercepted passes going back to the 1950 season.

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RUSH YDS/G

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2025 Division Standings
TEAMWLTPCT
13
4
0
.765
12
5
0
.706
Colts Colts
8
9
0
.471
3
14
0
.176
Last Game
IND Colts

8 - 9

30

Final

38

HOU Texans

12 - 5

Sun 4 Jan 2026

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NFL 2025 Rankings

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NFL 2025 Standings

AFC EastWLTPCT
14
3
0
.824
Bills Bills - w
12
5
0
.706
7
10
0
.412
Jets Jets - e
3
14
0
.176
AFC NorthWLTPCT
10
7
0
.588
8
9
0
.471
6
11
0
.353
5
12
0
.294
AFC SouthWLTPCT
13
4
0
.765
12
5
0
.706
Colts Colts - e
8
9
0
.471
3
14
0
.176
AFC WestWLTPCT
14
3
0
.824
11
6
0
.647
6
11
0
.353
3
14
0
.176
NFC EastWLTPCT
11
6
0
.647
7
9
1
.441
5
12
0
.294
4
13
0
.235
NFC NorthWLTPCT
Bears Bears - y
11
6
0
.647
9
7
1
.559
9
8
0
.529
Lions Lions - e
9
8
0
.529
NFC SouthWLTPCT
8
9
0
.471
8
9
0
.471
8
9
0
.471
6
11
0
.353
NFC WestWLTPCT
14
3
0
.824
Rams Rams - w
12
5
0
.706
49ers 49ers - w
12
5
0
.706
3
14
0
.176