Peyton Manning had the most passing yards in a Week-1 game in 2010, with 433 yards against the Texans on September 12, 2010.
- Regular season
| NAME | YDS | DATE | TM | OPP | CMP | ATT | PCT | AVG | TD | INT | RTG | TD% | INT% | SCK | SCKY | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | P. Manning | 433 | 9/12/2010 | @ | 40 | 57 | 70.2 | 7.6 | 3 | 0 | 109.8 | 5.3 | 0.0 | 2 | 14 | ||
| 2 |  | J. Cutler | 372 | 9/12/2010 | vs | 23 | 35 | 65.7 | 10.6 | 2 | 1 | 108.3 | 5.7 | 2.9 | 4 | 10 | ||
| 3 |  | C. Palmer | 345 | 9/12/2010 | @ | 34 | 50 | 68.0 | 6.9 | 2 | 1 | 92.5 | 4.0 | 2.0 | 1 | 4 | ||
| 4 |  | P. Rivers | 298 | 9/13/2010 | @ | 22 | 39 | 56.4 | 7.6 | 2 | 0 | 98.0 | 5.1 | 0.0 | 2 | 18 | ||
| 5 |  | D. Anderson | 297 | 9/12/2010 | @ | 22 | 41 | 53.7 | 7.2 | 1 | 0 | 85.1 | 2.4 | 0.0 | 2 | 31 | ||
| 6 | | K. Orton | 295 | 9/12/2010 | @ | 21 | 33 | 63.6 | 8.9 | 1 | 1 | 89.8 | 3.0 | 3.0 | 3 | 21 | ||
| 7 |  | T. Romo | 282 | 9/12/2010 | @ | 31 | 47 | 66.0 | 6.0 | 1 | 0 | 89.1 | 2.1 | 0.0 | 1 | 5 | ||
| 8 |  | E. Manning | 263 | 9/12/2010 | vs | 20 | 30 | 66.7 | 8.8 | 3 | 3 | 87.9 | 10.0 | 10.0 | 1 | 5 | ||
| 9 |  | T. Brady | 258 | 9/12/2010 | vs | 25 | 35 | 71.4 | 7.4 | 3 | 0 | 120.9 | 8.6 | 0.0 | 0 | 0 | ||
| 10 |  | S. Bradford | 253 | 9/12/2010 | vs | 32 | 55 | 58.2 | 4.6 | 1 | 3 | 53.1 | 1.8 | 5.5 | 2 | 13 | ||
| 11 |  | M. Ryan | 252 | 9/12/2010 | @ | 27 | 44 | 61.4 | 5.7 | 0 | 1 | 67.6 | 0.0 | 2.3 | 2 | 15 | ||
| 12 |  | J. Flacco | 248 | 9/13/2010 | @ | 20 | 38 | 52.6 | 6.5 | 0 | 1 | 62.2 | 0.0 | 2.6 | 2 | 15 | ||
| 13 |  | D. Brees | 237 | 9/9/2010 | vs | 27 | 36 | 75.0 | 6.6 | 1 | 0 | 101.3 | 2.8 | 0.0 | 1 | 8 | ||
| 14 | | D. Dixon | 236 | 9/12/2010 | vs | 18 | 26 | 69.2 | 9.1 | 0 | 1 | 81.6 | 0.0 | 3.8 | 3 | 25 | ||
| 15 | | J. Delhomme | 227 | 9/12/2010 | @ | 20 | 37 | 54.1 | 6.1 | 1 | 2 | 59.2 | 2.7 | 5.4 | 0 | 0 | ||
| 16 |  | A. Smith | 225 | 9/12/2010 | @ | 26 | 45 | 57.8 | 5.0 | 0 | 2 | 52.5 | 0.0 | 4.4 | 2 | 11 | ||
| 17 |  | A. Rodgers | 188 | 9/12/2010 | @ | 19 | 31 | 61.3 | 6.1 | 2 | 2 | 73.1 | 6.5 | 6.5 | 3 | 21 | ||
| 18 | | C. Henne | 182 | 9/12/2010 | @ | 21 | 34 | 61.8 | 5.4 | 0 | 0 | 75.9 | 0.0 | 0.0 | 3 | 18 | ||
| 19 | | M. Moore | 182 | 9/12/2010 | @ | 14 | 33 | 42.4 | 5.5 | 1 | 3 | 32.6 | 3.0 | 9.1 | 4 | 34 | ||
| 20 | | J. Freeman | 182 | 9/12/2010 | vs | 17 | 28 | 60.7 | 6.5 | 2 | 1 | 88.7 | 7.1 | 3.6 | 3 | 13 | ||
| 21 | | J. Campbell | 180 | 9/12/2010 | @ | 22 | 37 | 59.5 | 4.9 | 1 | 1 | 69.7 | 2.7 | 2.7 | 4 | 30 | ||
| 22 |  | M. Vick | 175 | 9/12/2010 | vs | 16 | 24 | 66.7 | 7.3 | 1 | 0 | 101.9 | 4.2 | 0.0 | 3 | 11 | ||
| 23 | | D. McNabb | 171 | 9/12/2010 | vs | 15 | 32 | 46.9 | 5.3 | 0 | 0 | 63.4 | 0.0 | 0.0 | 1 | 10 | ||
| 24 |  | B. Favre | 171 | 9/9/2010 | @ | 15 | 27 | 55.6 | 6.3 | 1 | 1 | 71.7 | 3.7 | 3.7 | 1 | 9 | ||
| 25 | | D. Garrard | 170 | 9/12/2010 | vs | 16 | 21 | 76.2 | 8.1 | 3 | 0 | 138.9 | 14.3 | 0.0 | 1 | 5 | ||
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More Colts Stats
Team Leaders 
PASS
166
Jones
RUSH
98
Taylor
REC
61
Pierce
Team Rankings
PPG
23.0
18th
OPP PPG
41.0
31st
RUSH YDS/G
102.0
20th
PASS YDS/G
166.0
26th
WAS
NFL 2026 Leaders
NFL 2026 Rankings
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NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
| NFC North | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
| NFC South | W | L | T | PCT |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
| NFC West | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 |
Bears
Rams| AFC East | W | L | T | PCT |
|---|---|---|---|---|
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
| AFC North | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
| AFC South | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
| AFC West | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 |
Jets