Aaron Rodgers had the most passing yards by a quarterback in a Week-11 game in 2021, with 385 yards against the Vikings on November 21, 2021.
| NAME | YDS | DATE | TM | OPP | CMP | ATT | PCT | AVG | TD | INT | RTG | TD% | INT% | SCK | SCKY | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | A. Rodgers | 385 | 11/21/2021 | @ | 23 | 33 | 69.7 | 11.7 | 4 | 0 | 148.4 | 12.1 | 0.0 | 2 | 13 | ||
| 2 |  | J. Herbert | 382 | 11/21/2021 | vs | 30 | 41 | 73.2 | 9.3 | 3 | 1 | 116.1 | 7.3 | 2.4 | 2 | 8 | ||
| 3 |  | K. Cousins | 341 | 11/21/2021 | vs | 24 | 35 | 68.6 | 9.7 | 3 | 0 | 128.4 | 8.6 | 0.0 | 2 | 23 | ||
| 4 |  | C. McCoy | 328 | 11/21/2021 | @ | 35 | 44 | 79.5 | 7.5 | 2 | 0 | 112.9 | 4.5 | 0.0 | 2 | 10 | ||
| 5 |  | R. Tannehill | 323 | 11/21/2021 | vs | 35 | 52 | 67.3 | 6.2 | 1 | 4 | 58.4 | 1.9 | 7.7 | 2 | 6 | ||
| 6 |  | T. Brady | 307 | 11/22/2021 | vs | 30 | 46 | 65.2 | 6.7 | 2 | 1 | 89.7 | 4.3 | 2.2 | 0 | 0 | ||
| 7 |  | J. Flacco | 291 | 11/21/2021 | vs | 24 | 39 | 61.5 | 7.5 | 2 | 0 | 101.5 | 5.1 | 0.0 | 2 | 13 | ||
| 8 |  | T. Tagovailoa | 273 | 11/21/2021 | @ | 27 | 33 | 81.8 | 8.3 | 2 | 1 | 108.7 | 6.1 | 3.0 | 0 | 0 | ||
| 9 |  | B. Roethlisberger | 273 | 11/21/2021 | @ | 28 | 44 | 63.6 | 6.2 | 3 | 0 | 103.7 | 6.8 | 0.0 | 3 | 28 | ||
| 10 |  | P. Mahomes | 260 | 11/21/2021 | vs | 23 | 37 | 62.2 | 7.0 | 0 | 1 | 71.9 | 0.0 | 2.7 | 3 | 16 | ||
| 11 | | T. Huntley | 219 | 11/21/2021 | @ | 26 | 36 | 72.2 | 6.1 | 0 | 1 | 76.0 | 0.0 | 2.8 | 6 | 43 | ||
| 12 |  | D. Prescott | 216 | 11/21/2021 | @ | 28 | 43 | 65.1 | 5.0 | 0 | 2 | 57.9 | 0.0 | 4.7 | 5 | 22 | ||
| 13 |  | D. Carr | 215 | 11/21/2021 | vs | 19 | 27 | 70.4 | 8.0 | 1 | 1 | 90.8 | 3.7 | 3.7 | 2 | 9 | ||
| 14 |  | T. Siemian | 214 | 11/21/2021 | @ | 22 | 40 | 55.0 | 5.4 | 3 | 2 | 74.4 | 7.5 | 5.0 | 0 | 0 | ||
| 15 |  | J. Allen | 209 | 11/21/2021 | vs | 21 | 35 | 60.0 | 6.0 | 2 | 2 | 72.2 | 5.7 | 5.7 | 1 | 8 | ||
| 16 |  | R. Wilson | 207 | 11/21/2021 | vs | 14 | 26 | 53.8 | 8.0 | 0 | 0 | 80.1 | 0.0 | 0.0 | 4 | 27 | ||
| 17 |  | M. Jones | 207 | 11/18/2021 | @ | 22 | 26 | 84.6 | 8.0 | 1 | 1 | 96.6 | 3.8 | 3.8 | 3 | 33 | ||
| 18 |  | T. Heinicke | 206 | 11/21/2021 | @ | 16 | 22 | 72.7 | 9.4 | 3 | 0 | 141.3 | 13.6 | 0.0 | 3 | 27 | ||
| 19 |  | A. Dalton | 201 | 11/21/2021 | vs | 11 | 23 | 47.8 | 8.7 | 2 | 0 | 107.3 | 8.7 | 0.0 | 1 | 18 | ||
| 20 |  | C. Newton | 189 | 11/21/2021 | vs | 21 | 27 | 77.8 | 7.0 | 2 | 0 | 120.5 | 7.4 | 0.0 | 1 | 3 | ||
| 21 |  | J. Garoppolo | 176 | 11/21/2021 | @ | 16 | 22 | 72.7 | 8.0 | 2 | 0 | 126.3 | 9.1 | 0.0 | 2 | 14 | ||
| 22 |  | B. Mayfield | 176 | 11/21/2021 | vs | 15 | 29 | 51.7 | 6.1 | 1 | 2 | 53.2 | 3.4 | 6.9 | 1 | 11 | ||
| 23 |  | D. Jones | 167 | 11/22/2021 | @ | 23 | 38 | 60.5 | 4.4 | 1 | 2 | 57.7 | 2.6 | 5.3 | 2 | 18 | ||
| 24 |  | T. Lawrence | 158 | 11/21/2021 | vs | 16 | 25 | 64.0 | 6.3 | 0 | 0 | 81.8 | 0.0 | 0.0 | 3 | 12 | ||
| 25 |  | M. Ryan | 153 | 11/18/2021 | vs | 19 | 28 | 67.9 | 5.5 | 0 | 2 | 51.6 | 0.0 | 7.1 | 4 | 33 | ||
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| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 13 | 3 | 0 | .813 |
 Bills - w | 11 | 5 | 0 | .688 |
 Dolphins - e | 7 | 9 | 0 | .438 |
 Jets - e | 3 | 13 | 0 | .188 |
| AFC North | W | L | T | PCT |
9 | 7 | 0 | .563 | |
8 | 8 | 0 | .500 | |
 Bengals - e | 6 | 10 | 0 | .375 |
 Browns - e | 4 | 12 | 0 | .250 |
| AFC South | W | L | T | PCT |
 Jaguars - x | 12 | 4 | 0 | .750 |
 Texans - x | 11 | 5 | 0 | .688 |
 Colts - e | 8 | 8 | 0 | .500 |
 Titans - e | 3 | 13 | 0 | .188 |
| AFC West | W | L | T | PCT |
 Broncos - y | 13 | 3 | 0 | .813 |
 Chargers - w | 11 | 5 | 0 | .688 |
 Chiefs - e | 6 | 10 | 0 | .375 |
 Raiders - e | 2 | 14 | 0 | .125 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 5 | 0 | .688 |
 Cowboys - e | 7 | 8 | 1 | .469 |
 Commanders - e | 4 | 12 | 0 | .250 |
 Giants - e | 3 | 13 | 0 | .188 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 5 | 0 | .688 |
 Packers - w | 9 | 6 | 1 | .594 |
 Vikings - e | 8 | 8 | 0 | .500 |
 Lions - e | 8 | 8 | 0 | .500 |
| NFC South | W | L | T | PCT |
8 | 8 | 0 | .500 | |
7 | 9 | 0 | .438 | |
 Falcons - e | 7 | 9 | 0 | .438 |
 Saints - e | 6 | 10 | 0 | .375 |
| NFC West | W | L | T | PCT |
 Seahawks - x | 13 | 3 | 0 | .813 |
 49ers - x | 12 | 4 | 0 | .750 |
 Rams - x | 11 | 5 | 0 | .688 |
 Cardinals - e | 3 | 13 | 0 | .188 |
