Fred Dryer has scored the most safeties by a defensive lineman in a game, with 2 safeties against the Packers on October 21, 1973.
Interpreted as:
most safeties in a regular-season game by a defensive lineman| NAME | SFTY | DATE | TM | OPP | TKL | AST | COMB | SCK | SCKY | INT | INT YDS | INT TD | FF | FR | FR TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | F. Dryer | 2 | 10/21/1973 |  LA | vs |  GB | 0 | 0 | 0 | 0 | |||||||
| 2 | | A.J. Epenesa | 1 | 12/29/2024 |  BUF | vs |  NYJ | 4 | 0 | 4 | 1.0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
| 3 | | Z. Harrison | 1 | 12/16/2024 |  ATL | @ |  LV | 2 | 2 | 4 | 1.0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
| 4 | | S. Hubbard | 1 | 10/6/2024 |  CIN | vs |  BAL | 7 | 2 | 9 | 1.0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 |
| 5 | | A. Wright | 1 | 9/15/2024 |  CLE | @ |  JAX | 2 | 1 | 3 | 1.0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
| 6 | | Z. Allen | 1 | 9/8/2024 |  DEN | @ |  SEA | 1 | 1 | 2 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 7 | | P. O'Connor | 1 | 12/10/2023 |  TB | @ | ATL | 1 | 0 | 1 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 8 | | C. Campbell | 1 | 11/5/2023 | ATL | vs |  MIN | 4 | 0 | 4 | 1.0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 9 | | S. Williams | 1 | 10/29/2023 |  DAL | vs |  LAR | 1 | 1 | 2 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 10 | | J. Johnson | 1 | 12/11/2022 |  NYJ | @ | BUF | 0 | 0 | 0 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 11 | | R. Lopez | 1 | 12/4/2022 |  HOU | vs | CLE | 5 | 0 | 5 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 12 | | E. Oliver | 1 | 11/24/2022 | BUF | @ |  DET | 4 | 2 | 6 | 1.0 | 3 | 0 | 0 | 0 | 1 | 1 | 0 |
| 13 | | F. Clark | 1 | 10/23/2022 |  KC | @ |  SF | 1 | 1 | 2 | 1.5 | 7.5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 14 | | S. Joseph-Day | 1 | 10/23/2022 |  LAC | vs | SEA | 2 | 2 | 4 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 15 | | D. Payne | 1 | 9/25/2022 |  WAS | vs |  PHI | 1 | 2 | 3 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 16 | | M. Purcell | 1 | 9/25/2022 | DEN | vs | SF | 4 | 1 | 5 | 1.0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
| 17 | | A. Blackson | 1 | 1/2/2022 |  CHI | vs |  NYG | 3 | 0 | 3 | 1.0 | 9 | 0 | 0 | 0 | 0 | 0 | 0 |
| 18 | | J. Martin | 1 | 10/24/2021 | HOU | @ |  ARI | 2 | 2 | 4 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 19 | | I. Rochell | 1 | 1/3/2021 | LAC | @ | KC | 1 | 1 | 2 | 1.0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 20 | | R. Okwara | 1 | 12/20/2020 | DET | @ |  TEN | 4 | 0 | 4 | 1.0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 21 |  | C. Jones | 1 | 12/13/2020 | KC | @ |  MIA | 4 | 0 | 4 | 1.0 | 6 | 0 | 0 | 0 | 0 | 0 | 0 |
| 22 |  | J. Houston | 1 | 12/6/2020 |  IND | @ | HOU | 4 | 0 | 4 | 3.0 | 25 | 0 | 0 | 0 | 1 | 0 | 0 |
| 23 | | I. Odenigbo | 1 | 12/6/2020 | MIN | vs | JAX | 1 | 1 | 2 | 1.0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 24 | | O. Vernon | 1 | 11/22/2020 | CLE | vs | PHI | 4 | 1 | 5 | 3.0 | 6 | 0 | 0 | 0 | 0 | 0 | 0 |
| 25 | | J. Allen | 1 | 10/25/2020 |  WAS | vs | DAL | 2 | 0 | 2 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Results may be incomplete. StatMuse has complete game-level data for safeties going back to the 1960 season.
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