25 players are tied for the most interception touchdowns in a game, scoring 2 touchdowns. The first three are Zach Brown on December 30, 2012, Janoris Jenkins on November 25, 2012 and David Bowens on October 24, 2010.

what is the most interception return touchdowns in a game
Interpreted as:
What is the most interception return touchdowns by a player in a regular-season game?
Results may be incomplete. StatMuse has complete game-level data for interception touchdowns going back to the 1950 season.

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