The San Francisco 49ers have a record of 14-10 against the spread against the NFC West since January 9, 2022.
| TEAM | DATE | ATS | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 1/9/2022 | 1-0 |  SF | +151 | @ |  LAR | -178 | W 27-24 | +3.5 | +6.5 (Y) | 46.5 | +4.5 (O) | 3 | 23 | 449 | 265 | 64.3 | |
| 2 | | 49ers | 9/18/2022 | 1-0 | SF | -394 | vs |  SEA | +306 | W 27-7 | -8.5 | +11.5 (Y) | 39.5 | -5.5 (U) | 3 | 25 | 373 | 216 | 40.0 | 66.7 |
| 3 | | 49ers | 10/3/2022 | 1-0 | SF | -125 | vs | LAR | +105 | W 24-9 | -2 | +13 (Y) | 42 | -9 (U) | 3 | 13 | 327 | 257 | 41.7 | 0.0 |
| 4 | | 49ers | 10/30/2022 | 1-0 | SF | -107 | @ | LAR | -113 | W 31-14 | -1.5 | +15.5 (Y) | 42 | +3 (O) | 4 | 22 | 368 | 223 | 55.6 | |
| 5 | | 49ers | 11/21/2022 | 1-0 | SF | -442 | @ |  ARI | +341 | W 38-10 | -9.5 | +18.5 (Y) | 43 | +5 (O) | 5 | 21 | 387 | 314 | 54.5 | |
| 6 | | 49ers | 12/15/2022 | 1-0 | SF | -181 | @ | SEA | +152 | W 21-13 | -3 | +5 (Y) | 42.5 | -8.5 (U) | 3 | 15 | 381 | 277 | 46.2 | |
| 7 | | 49ers | 1/8/2023 | 1-0 | SF | -1057 | vs | ARI | +693 | W 38-13 | -14.5 | +10.5 (Y) | 39.5 | +11.5 (O) | 5 | 21 | 311 | 255 | 46.2 | 0.0 |
| 8 | | 49ers | 9/17/2023 | 0-1 | SF | -343 | @ | LAR | +273 | W 30-23 | -7.5 | -0.5 (N) | 45 | +8 (O) | 3 | 21 | 365 | 386 | 22.2 | |
| 9 | | 49ers | 10/1/2023 | 1-0 | SF | -1106 | vs | ARI | +692 | W 35-16 | -14.5 | +4.5 (Y) | 44 | +7 (O) | 5 | 30 | 395 | 362 | 60.0 | 100.0 |
| 10 | | 49ers | 11/23/2023 | 1-0 | SF | -334 | @ | SEA | +260 | W 31-13 | -7 | +11 (Y) | 43 | +1 (O) | 4 | 23 | 377 | 220 | 45.5 | |
| 11 | | 49ers | 12/10/2023 | 0-1 | SF | -1099 | vs | SEA | +683 | W 28-16 | -14.5 | -2.5 (N) | 44.5 | -0.5 (U) | 4 | 19 | 527 | 324 | 54.5 | |
| 12 | | 49ers | 12/17/2023 | 1-0 | SF | -771 | @ | ARI | +529 | W 45-29 | -12.5 | +3.5 (Y) | 48 | +26 (O) | 6 | 24 | 406 | 436 | 57.1 | |
| 13 | | 49ers | 1/7/2024 | 0-1 | SF | -246 | vs | LAR | +199 | L 20-21 | -5.5 | -6.5 (N) | 40 | +1 (O) | 3 | 20 | 300 | 258 | 50.0 | 100.0 |
| 14 | | 49ers | 9/22/2024 | 0-1 | SF | -270 | @ | LAR | +220 | L 24-27 | -6 | -9 (N) | 44.5 | +6.5 (O) | 3 | 25 | 425 | 296 | 54.5 | 100.0 |
| 15 | | 49ers | 10/6/2024 | 0-1 | SF | -350 | vs | ARI | +278 | L 23-24 | -7.5 | -8.5 (N) | 48.5 | -1.5 (U) | 2 | 22 | 384 | 358 | 54.5 | 0.0 |
| 16 | | 49ers | 10/10/2024 | 1-0 | SF | -199 | @ | SEA | +165 | W 36-24 | -3.5 | +8.5 (Y) | 49 | +11 (O) | 4 | 21 | 483 | 358 | 41.7 | |
| 17 | | 49ers | 11/17/2024 | 0-1 | SF | -262 | vs | SEA | +214 | L 17-20 | -6 | -9 (N) | 48.5 | -11.5 (U) | 2 | 21 | 277 | 289 | 63.6 | |
| 18 | | 49ers | 12/12/2024 | 0-1 | SF | -156 | vs | LAR | +131 | L 6-12 | -3 | -9 (N) | 48.5 | -30.5 (U) | 0 | 11 | 191 | 302 | 25.0 | |
| 19 | | 49ers | 1/5/2025 | 0-1 | SF | +188 | @ | ARI | -229 | L 24-47 | +4.5 | -18.5 (N) | 43 | +28 (O) | 3 | 26 | 436 | 393 | 38.5 | 50.0 |
| 20 | | 49ers | 9/7/2025 | 1-0 | SF | -139 | @ | SEA | +117 | W 17-13 | -2.5 | +1.5 (Y) | 43.5 | -13.5 (U) | 2 | 24 | 384 | 230 | 50.0 | 100.0 |
| 21 | | 49ers | 9/21/2025 | 0-1 | SF | -123 | vs | ARI | +103 | W 16-15 | -1.5 | -0.5 (N) | 44.5 | -13.5 (U) | 1 | 19 | 355 | 260 | 20.0 | 50.0 |
| 22 | | 49ers | 10/2/2025 | 1-0 | SF | +344 | @ | LAR | -444 | W 26-23 | +8.5 | +11.5 (Y) | 43.5 | +5.5 (O) | 2 | 27 | 407 | 456 | 38.9 | 100.0 |
| 23 | | 49ers | 11/9/2025 | 0-1 | SF | +210 | vs | LAR | -254 | L 26-42 | +5.5 | -10.5 (N) | 49.5 | +18.5 (O) | 4 | 24 | 393 | 401 | 37.5 | 33.3 |
| 24 | | 49ers | 11/16/2025 | 1-0 | SF | -191 | @ | ARI | +158 | W 41-22 | -3.5 | +15.5 (Y) | 48.5 | +14.5 (O) | 5 | 24 | 281 | 488 | 33.3 | |
| Average | 2.4 | 3.3 | 21.7 | 374.3 | 317.7 | 45.4 | 5.2 | |||||||||||||
| Total | 14-10 | 79 | 521 | 8,982 | 7,624 | 45.4 | 61.9 |
StatMuse has team, game-level data for spread records going back to the 1979 season.
More 49ers Stats
Team Rankings
PPG
23.7
14th
OPP PPG
22.9
16th
RUSH YDS/G
94.8
28th
PASS YDS/G
267.0
3rd
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