The San Francisco 49ers have a record of 80-71 against the AFC in the regular-season and playoffs since December 13, 1989.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 12/17/1989 | 1-0 |  SF | vs |  BUF | W 21-10 | 1.000 | 3 | 18 | 283 | 301 | ||
| 2 | | 49ers | 1/28/1990 | 1-0 | SF | @ |  DEN | W 55-10 | 1.000 | 8 | 28 | 461 | 167 | ||
| 3 | | 49ers | 10/7/1990 | 1-0 | SF | @ |  HOU | W 24-21 | 1.000 | 3 | 17 | 383 | 256 | ||
| 4 | | 49ers | 10/21/1990 | 1-0 | SF | vs |  PIT | W 27-7 | 1.000 | 3 | 22 | 304 | 200 | ||
| 5 | | 49ers | 10/28/1990 | 1-0 | SF | vs |  CLE | W 20-17 | 1.000 | 2 | 20 | 294 | 274 | ||
| 6 | | 49ers | 12/9/1990 | 1-0 | SF | @ |  CIN | W 20-17 | 1.000 | 2 | 25 | 372 | 215 | ||
| 7 | | 49ers | 9/8/1991 | 1-0 | SF | vs |  SD | W 34-14 | 1.000 | 4 | 24 | 458 | 326 | 36.4 | 0.0 |
| 8 | | 49ers | 9/29/1991 | 0-1 | SF | @ |  RAI | L 6-12 | .000 | 0 | 17 | 339 | 220 | 36.4 | 0.0 |
| 9 | | 49ers | 12/8/1991 | 1-0 | SF | @ |  SEA | W 24-22 | 1.000 | 3 | 19 | 329 | 278 | 50.0 | |
| 10 | | 49ers | 12/14/1991 | 1-0 | SF | vs |  KC | W 28-14 | 1.000 | 4 | 24 | 408 | 310 | 40.0 | 100.0 |
| 11 | | 49ers | 9/13/1992 | 0-1 | SF | vs | BUF | L 31-34 | .000 | 4 | 26 | 598 | 488 | 61.5 | 100.0 |
| 12 | | 49ers | 9/20/1992 | 1-0 | SF | @ |  NYJ | W 31-14 | 1.000 | 4 | 19 | 335 | 311 | 46.2 | 0.0 |
| 13 | | 49ers | 10/11/1992 | 1-0 | SF | @ |  NE | W 24-12 | 1.000 | 3 | 24 | 411 | 227 | 37.5 | 0.0 |
| 14 | | 49ers | 12/6/1992 | 1-0 | SF | vs |  MIA | W 27-3 | 1.000 | 4 | 20 | 356 | 239 | 53.8 | 100.0 |
| 15 | | 49ers | 9/5/1993 | 1-0 | SF | @ | PIT | W 24-13 | 1.000 | 3 | 21 | 326 | 211 | 41.7 | |
| 16 | | 49ers | 9/13/1993 | 0-1 | SF | @ | CLE | L 13-23 | .000 | 1 | 22 | 396 | 304 | 33.3 | 0.0 |
| 17 | | 49ers | 12/5/1993 | 1-0 | SF | vs | CIN | W 21-8 | 1.000 | 3 | 19 | 284 | 339 | 37.5 | 100.0 |
| 18 | | 49ers | 12/25/1993 | 0-1 | SF | vs | HOU | L 7-10 | .000 | 1 | 20 | 337 | 311 | 46.2 | |
| 19 | | 49ers | 9/5/1994 | 1-0 | SF | vs | RAI | W 44-14 | 1.000 | 6 | 24 | 448 | 181 | 40.0 | 100.0 |
| 20 | | 49ers | 9/11/1994 | 0-1 | SF | @ | KC | L 17-24 | .000 | 2 | 23 | 381 | 292 | 54.5 | |
| 21 | | 49ers | 12/11/1994 | 1-0 | SF | @ | SD | W 38-15 | 1.000 | 5 | 27 | 417 | 378 | 40.0 | 50.0 |
| 22 | | 49ers | 12/17/1994 | 1-0 | SF | vs | DEN | W 42-19 | 1.000 | 6 | 25 | 488 | 334 | 66.7 | 100.0 |
| 23 | | 49ers | 1/29/1995 | 1-0 | SF | vs | SD | W 49-26 | 1.000 | 7 | 28 | 455 | 354 | 53.8 | |
| 24 | | 49ers | 9/17/1995 | 1-0 | SF | vs | NE | W 28-3 | 1.000 | 4 | 21 | 363 | 302 | 38.5 | 100.0 |
| 25 | | 49ers | 10/15/1995 | 0-1 | SF | @ |  IND | L 17-18 | .000 | 2 | 21 | 269 | 257 | 50.0 | 0.0 |
| Average | .530 | 2.6 | 20.0 | 351.2 | 325.4 | ||||||||||
| Total | 80-71 | .530 | 395 | 3,015 | 53,036 | 49,141 | |||||||||
More 49ers Stats
Team Rankings
PPG
20.8
24th
OPP PPG
21.3
14th
RUSH YDS/G
82.2
30th
PASS YDS/G
306.3
1st
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Jaguars | NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles | 4 | 2 | 0 | .667 |
 Commanders | 3 | 2 | 0 | .600 |
| NFC North | W | L | T | PCT |
 Packers | 3 | 1 | 1 | .700 |
 Lions | 4 | 2 | 0 | .667 |
| NFC South | W | L | T | PCT |
 Buccaneers | 5 | 1 | 0 | .833 |
 Panthers | 3 | 3 | 0 | .500 |
| NFC West | W | L | T | PCT |
| 49ers | 4 | 2 | 0 | .667 |
| Seahawks | 4 | 2 | 0 | .667 |
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