Since 2018, the Carolina Panthers have the worst record by a team as favorites when playing 20+ games, with a record of 10-16.

worst record by a favored team since 2018, min 20 games
PanthersCardinalsFalconsBroncos49ersChargersCowboysRaidersEaglesTitansSteelersTexansPatriotsBrownsRavensVikingsBuccaneersSeahawksRamsColtsSaintsBears10-1610-1414-1512-1220-1725-1925-1712-822-13-124-1325-13-218-935-1724-1134-1526-11-129-1230-1240-1629-1135-1123-7
TEAMGPRECW%WLTTDPTSPPGOPP PTSOPP PPG1DWN3DWN%4DWN%
Carolina PanthersCarolina Panthers2610-16.385101606555721.461323.652831.542.6
Arizona CardinalsArizona Cardinals2410-14.417101406556023.357123.851039.159.1
Atlanta FalconsAtlanta Falcons2914-15.483141508272925.171224.665444.540.7
Denver BroncosDenver Broncos2412-12.500121205449620.742417.746834.971.0
San Francisco 49ersSan Francisco 49ers3720-17.5412017011396326.082922.480641.845.2
Los Angeles ChargersLos Angeles Chargers4425-19.568251901311,13025.798722.41,00342.960.4
Dallas CowboysDallas Cowboys4225-17.595251701401,20028.696823.097443.954.2
Las Vegas RaidersLas Vegas Raiders2012-8.60012804845022.550125.142440.260.9
Philadelphia EaglesPhiladelphia Eagles3622-13-1.6252213110391625.473520.482444.647.3
Tennessee TitansTennessee Titans3724-13.6492413011895225.778721.379843.152.8
Pittsburgh SteelersPittsburgh Steelers4025-13-2.6502513211096624.278519.681039.545.2
Houston TexansHouston Texans2718-9.66718907367525.059822.156140.563.0
New England PatriotsNew England Patriots5235-17.673351701571,37926.591017.51,15441.553.2
Cleveland BrownsCleveland Browns3524-11.686241109278022.371120.372943.140.0
Baltimore RavensBaltimore Ravens4934-15.694341501561,36527.993119.01,13345.662.3
Minnesota VikingsMinnesota Vikings3826-11-1.697261111201,01826.880721.279339.043.6
Tampa Bay BuccaneersTampa Bay Buccaneers4129-12.707291201441,20529.489621.997645.556.4
Seattle SeahawksSeattle Seahawks4230-12.714301201381,14427.291221.785838.656.3
Los Angeles RamsLos Angeles Rams5640-16.714401601751,51827.11,16220.81,24842.242.4
Indianapolis ColtsIndianapolis Colts4029-11.725291101291,10327.678719.789241.458.3
New Orleans SaintsNew Orleans Saints4635-11.761351101581,33929.195720.81,02043.156.1
Chicago BearsChicago Bears3023-7.76723708271723.950516.860436.763.6
Green Bay PackersGreen Bay Packers4837-11.771371101601,29727.01,02721.41,03744.458.9
Buffalo BillsBuffalo Bills3527-8.771278011395827.462017.780747.351.6
Kansas City ChiefsKansas City Chiefs5645-11.804451101981,67029.81,16520.81,35749.367.3