Roman Josi had the most assists by a defenseman in 2021-22, with 73 assists.

	NAME	A	SEASON	TM	GP	G	P	+/-	PIM	PPG	PPA	SHG	SHA	GWG	OTG	S	S%	FOW	FO	FOW%	HIT	BKS	TKA	GVA	TOI/GP
1	Roman Josi R. Josi	73	2021-22	NSH	80	23	96	+13	46	11	26	0	0	2	0	281	8.2	0	0		66	133	48	71	25:33
2	Victor Hedman V. Hedman	65	2021-22	TBL	82	20	85	+26	36	6	32	0	0	6	1	219	9.1	0	0		93	129	52	56	25:05
3	Adam Fox A. Fox	63	2021-22	NYR	78	11	74	+18	26	0	33	1	1	2	1	158	7.0	0	0		30	128	78	58	23:54
4	Quinn Hughes Q. Hughes	60	2021-22	VAN	76	8	68	+10	28	0	31	0	2	1	1	150	5.3	0	0		19	56	41	42	25:15
5	Kris Letang K. Letang	58	2021-22	PIT	78	10	68	+20	49	2	20	0	0	3	2	214	4.7	0	0		171	122	59	79	25:47
6	Morgan Rielly M. Rielly	58	2021-22	TOR	82	10	68	+16	40	2	21	0	3	3	0	221	4.5	0	0		92	87	40	76	23:44
7	Cale Makar C. Makar	58	2021-22	COL	77	28	86	+48	26	9	25	0	0	6	3	240	11.7	0	0		95	110	49	40	25:40
8	John Carlson J. Carlson	54	2021-22	WSH	78	17	71	+13	20	7	18	0	3	2	0	195	8.7	0	0		73	112	42	55	23:49
9	Seth Jones S. Jones	46	2021-22	CHI	78	5	51	-37	28	0	19	0	1	0	0	194	2.6	0	0		99	155	34	71	26:13
10	Rasmus Andersson R. Andersson	46	2021-22	CGY	82	4	50	+30	28	2	17	0	1	1	0	152	2.6	0	0		63	125	24	44	22:40
11	Charlie McAvoy C. McAvoy	46	2021-22	BOS	78	10	56	+31	66	4	17	1	0	5	1	166	6.0	0	0		155	130	29	65	24:38
12	Brent Burns B. Burns	44	2021-22	SJS	82	10	54	-15	42	4	14	0	1	0	0	203	4.9	0	1	0.0	55	150	68	97	26:09
13	Devon Toews D. Toews	44	2021-22	COL	66	13	57	+52	20	2	10	0	0	3	1	158	8.2	0	0		54	85	45	34	25:22
14	Moritz Seider M. Seider	43	2021-22	DET	82	7	50	-9	34	2	19	0	2	4	2	187	3.7	0	0		151	161	41	48	23:02
15	Aaron Ekblad A. Ekblad	42	2021-22	FLA	61	15	57	+38	26	3	17	0	3	2	2	180	8.3	0	0		62	69	43	73	24:55
16	Tony DeAngelo T. DeAngelo	41	2021-22	CAR	64	10	51	+30	56	2	18	0	0	2	0	151	6.6	0	0		41	59	27	39	19:49
17	John Klingberg J. Klingberg	41	2021-22	DAL	74	6	47	-28	34	1	19	0	0	2	2	139	4.3	0	0		57	77	16	86	22:13
18	Rasmus Dahlin R. Dahlin	40	2021-22	BUF	80	13	53	-22	68	3	18	0	1	3	1	170	7.6	0	0		121	91	27	51	24:01
19	Noah Hanifin N. Hanifin	38	2021-22	CGY	81	10	48	+27	19	1	12	0	1	1	0	189	5.3	0	0		63	84	38	62	21:18
20	Jaccob Slavin J. Slavin	38	2021-22	CAR	79	4	42	+35	10	1	6	0	2	0	0	165	2.4	0	0		50	121	74	43	23:32
21	Shea Theodore S. Theodore	38	2021-22	VGK	78	14	52	+6	24	1	11	0	0	5	3	205	6.8	0	0		37	97	60	58	23:08
22	Noah Dobson N. Dobson	38	2021-22	NYI	80	13	51	-3	18	3	19	0	0	4	1	190	6.8	0	0		78	154	27	82	21:28
23	Shayne Gostisbehere S. Gostisbehere	37	2021-22	ARI	82	14	51	-23	26	2	17	0	0	2	1	151	9.3	0	0		60	115	44	78	22:11
24	Zach Werenski Z. Werenski	37	2021-22	CBJ	68	11	48	-15	22	4	10	0	1	2	0	216	5.1	0	0		33	95	39	39	25:40
25	MacKenzie Weegar M. Weegar	36	2021-22	FLA	80	8	44	+40	81	1	2	1	1	2	0	203	3.9	0	0		179	156	74	85	23:22