Francesco Acerbi has made the most appearances by a defender in Europe's top five leagues with 3+ interceptions, with 127 appearances in Serie A.

most 3 or more interception games by defender

	NAME	M	INT	START	MIN	G	A	TKL	TKL-W	TKL-LM	SH-BLK	CLR	FOUL	YC	RC
1	Francesco Acerbi F. Acerbi	127	540	127	11,402	10	2	173	144	1	16	681	90	23	3
2	Armando Izzo A. Izzo	98	399	96	8,546	7	2	213	151	1	7	398	140	28	2
3	Hilton	96	396	96	8,580	3	0	150	105	4	14	588	73	4	1
4	Frédéric Guilbert F. Guilbert	95	373	93	8,396	1	7	308	215	0	14	326	133	20	0
5	Stefan Bell S. Bell	95	368	93	8,361	4	5	152	105	0	18	479	152	34	1
6	Mats Hummels M. Hummels	90	357	89	7,810	7	4	191	131	2	4	331	75	17	1
7	Daniel Congré D. Congré	89	378	88	7,961	4	2	200	152	0	2	359	94	10	0
8	Laurent Koscielny L. Koscielny	87	357	87	7,767	8	1	128	85	1	5	530	62	10	0
9	Alexander Djiku A. Djiku	85	348	84	7,575	2	1	180	128	4	9	444	124	22	2
10	Diego Godín D. Godín	85	338	84	7,481	5	1	164	113	1	9	411	105	21	1
11	Nicolas Nkoulou N. Nkoulou	82	330	82	7,349	4	0	129	97	2	5	382	95	18	1
12	Germán Pezzella G. Pezzella	80	308	78	7,088	4	1	135	94	1	6	387	102	18	1
13	José Luis Palomino J. Luis Palomino	79	328	77	6,905	3	1	180	105	0	5	266	124	17	1
14	Shkodran Mustafi S. Mustafi	79	349	78	7,007	8	0	168	116	2	9	462	88	22	0
15	Andrea Masiello A. Masiello	78	306	77	6,709	2	2	135	93	0	11	326	74	20	0
16	Aïssa Mandi A. Mandi	78	298	77	6,938	7	2	120	83	1	7	283	67	11	1
17	Hugo Mallo H. Mallo	77	312	77	6,886	4	8	202	134	0	11	221	133	22	1
18	Gabriel Paulista G. Paulista	76	308	74	6,694	2	2	99	68	1	3	387	55	17	1
19	Yeray Álvarez Y. Álvarez	75	294	74	6,697	1	0	123	82	1	8	300	102	17	0
20	Íñigo Martínez Í. Martínez	75	276	74	6,670	6	1	118	73	0	18	351	91	17	0
21	Jeffrey Gouweleeuw J. Gouweleeuw	73	274	73	6,562	0	1	118	76	1	3	381	81	17	1
22	Chris Smalling C. Smalling	73	274	71	6,536	6	3	100	63	1	18	424	73	8	0
23	Jonny Otto J. Otto	72	294	71	6,431	3	6	206	149	2	8	137	111	23	1
24	Víctor Ruíz V. Ruíz	72	292	71	6,418	2	2	72	41	3	3	365	61	14	1
25	Nacho Monreal N. Monreal	72	309	71	6,403	1	3	169	115	0	9	254	64	8	0