Jordan Ayew has made the most career appearances by a Ghanaian in the Premier League, with 305 appearances.

most appearances by a player in the premier league ghana

	NAME	M	MIN	START	G	G/M	A	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	Jordan Ayew J. Ayew	305	21,479	246	42	0.14	25	67	3	0	396	135	10	12,052	729	66
2	Jeffrey Schlupp J. Schlupp	280	16,775	188	22	0.08	14	36	0	0	232	75	3	9,489	334	3
3	Michael Essien M. Essien	169	13,356	150	17	0.10	10	27	0
4	Thomas Partey T. Partey	130	9,643	109	9	0.07	5	14	0	0	132	29	4	8,291	104	1
5	Daniel Amartey D. Amartey	107	7,342	80	2	0.02	1	3	0	0	30	11	0	5,627	33	2
6	Tariq Lamptey T. Lamptey	104	5,280	57	3	0.03	9	12	0	0	44	8	0	3,672	130	7
7	André Ayew A. Ayew	102	6,529	70	21	0.21	9	30	0	1	131	54	5	3,240	117	21
8	John Paintsil J. Paintsil	94	7,553	81	0	0.00	2	2	0
9	Antoine Semenyo A. Semenyo	90	6,383	72	26	0.29	10	36	1	1	219	84	7	3,514	387	24
10	Christian Atsu C. Atsu	80	4,121	41	3	0.04	6	9	0	0	72	28	0	2,021	126	14
11	Mohammed Kudus M. Kudus	74	5,881	67	14	0.19	13	27	0	0	156	44	9	3,536	283	40
12	Mohammed Salisu M. Salisu	68	5,786	62	0	0.00	1	1	0	0	47	16	0	4,450	65	3
13	Tony Yeboah T. Yeboah	47	3,874	44	24	0.51	3	27	0
14	Kamal Deen Sulemana K. Deen Sulemana	44	2,373	27	3	0.07	2	5	0	0	54	15	2	1,162	113	5
15	Sulley Muntari S. Muntari	38	2,911	34	5	0.13	5	10	1
16	Kevin-Prince Boateng K. Boateng	36	2,448	27	3	0.08	2	5	1
17	Denis Odoi D. Odoi	34	2,864	32	0	0.00	1	1	0	0	12	2	0	2,110	17	1
18	Asamoah Gyan A. Gyan	34	2,233	23	10	0.29	4	14	0
19	John Mensah J. Mensah	34	2,266	29	1	0.03	1	2	0
20	Alex Nyarko A. Nyarko	33	2,289	26	1	0.03	0	1	0
21	Richard Kingson R. Kingson	25	2,138	23	0	0.00	0	0	0
22	Emmanuel Frimpong E. Frimpong	17	731	10	0	0.00	2	2	0
23	Abdul Rahman Baba A. Rahman Baba	15	1,016	11	0	0.00	1	1	0	0	6	2	0	853	0	2
24	Quincy Owusu-Abeyie Q. Owusu-Abeyie	15	475	4	0	0.00	0	0	0
25	Nii Lamptey N. Lamptey	12	547	4	0	0.00	1	1	0