Between the 1999-00 and 2009-10 seasons, Thierry Henry scored the most goals in the Premier League, with 174 goals.

	NAME	G	M	MIN	START	G/M	A	G+A	PK
1	Thierry Henry T. Henry	174	254	21,219	235	0.69	74	248	23
2	Robbie Keane R. Keane	121	327	23,294	261	0.37	37	158	17
3	Frank Lampard F. Lampard	119	384	33,746	378	0.31	85	204	29
4	Michael Owen M. Owen	110	238	16,978	191	0.46	16	126	11
5	Alan Shearer A. Shearer	107	225	19,550	220	0.48	25	132	28
6	Wayne Rooney W. Rooney	106	256	19,386	213	0.41	49	155	4
7	Jermain Defoe J. Defoe	97	286	18,593	197	0.34	23	120	8
8	Ruud van Nistelrooy R. van Nistelrooy	95	150	12,181	137	0.63	14	109	18
9	Nicolas Anelka N. Anelka	93	246	20,084	227	0.38	31	124	7
10	Jimmy Floyd Hasselbaink J. Floyd Hasselbaink	93	219	15,812	178	0.42	39	132	13
11	Mark Viduka M. Viduka	92	240	18,233	207	0.38	28	120	5
12	Kevin Phillips K. Phillips	91	245	18,847	210	0.37	24	115	11
13	James Beattie J. Beattie	86	283	19,096	217	0.30	27	113	16
14	Didier Drogba D. Drogba	84	166	12,432	133	0.51	39	123	1
15	Cristiano Ronaldo C. Ronaldo	84	196	14,544	157	0.43	34	118	11
16	Andy Cole A. Cole	83	219	15,964	176	0.38	34	117	1
17	Emile Heskey E. Heskey	80	368	26,939	316	0.22	38	118	0
18	Steven Gerrard S. Gerrard	80	354	29,290	336	0.23	62	142	13
19	Yakubu Aiyegbeni Y. Aiyegbeni	77	208	15,887	180	0.37	23	100	14
20	Darren Bent D. Bent	74	171	12,949	140	0.43	11	85	12
21	Craig Bellamy C. Bellamy	74	245	19,240	218	0.30	27	101	3
22	Louis Saha L. Saha	73	217	14,016	149	0.34	18	91	12
23	Paul Scholes P. Scholes	69	315	24,411	276	0.22	36	105	1
24	Kevin Davies K. Davies	64	329	26,443	302	0.19	44	108	1
25	Robert Pirès R. Pirès	62	189	13,977	159	0.33	41	103	4