The Brooklyn Grooms have scored the most runs by a team in a game on September 7, with 21 runs versus the Chicago Colts on September 7, 1891.

	TEAM	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Grooms	21	9/7/1891	BKN	vs	CHI	W 21-3
2	Senators	20	9/7/1901	WSH	@	MIL	W 20-8	39	15	4	0	0	13	7	1	-10	3	-10	47	19	4	0		-10	-10	.385	.489	.487	.977
3	Brewers	17	9/7/1976	MIL	vs	CLE	W 17-4	42	20	6	0	1	14	8	1	8	0	0	51	29	7	0	0	1	1	.476	.569	.690	1.259
4	Braves	17	9/7/1941	BSN	vs	PHN	W 17-6	44	20	2	1	1	15	7	0	3	1	0	51	27	4	0			0	.455	.529	.614	1.143
5	Angels	16	9/7/1984	CAL	@	CWS	W 16-8	46	19	5	1	1	15	6	0	9	0	0	53	29	7	1	0	0	1	.413	.481	.630	1.111
6	Twins	16	9/7/1969	MIN	@	OAK	W 16-4	41	15	0	0	4	16	9	1	5	2	0	51	27	4	0	0	1	0	.366	.490	.659	1.149
7	Yankees	16	9/7/1968	NYY	vs	WSH	W 16-2	43	19	4	1	3	16	6	0	1	1	0	50	34	8	1	0	1	0	.442	.510	.791	1.301
8	Giants	16	9/7/1892	NYG	vs	PIT	W 16-6
9	Solons	16	9/7/1891	COL	@	WSH	W 16-7
10	Blue Jays	15	9/7/1998	TOR	vs	CLE	W 15-1	41	18	4	0	3	15	8	0	6	1	0	49	31	7	0	0	1	1	.439	.531	.756	1.287
11	Rockies	15	9/7/1998	COL	vs	FLA	W 15-10	41	21	3	0	4	13	5	0	4	1	1	48	36	7	2	0	0	1	.512	.565	.878	1.443
12	Cardinals	15	9/7/1993	STL	@	CIN	W 15-2	36	11	0	0	5	15	6	0	11	1	0	44	26	5	1	1	0	0	.306	.395	.722	1.118
13	Yankees	15	9/7/1978	NYY	@	BOS	W 15-3	47	21	4	1	0	15	4	1	8	0	0	54	27	5	1	1	0	0	.447	.491	.574	1.065
14	Indians	15	9/7/1959	CLE	vs	DET	W 15-14	37	16	3	1	3	15	7	0	5	0	0	46	30	7	2	0	0	1	.432	.523	.811	1.334
15	Tigers	15	9/7/1935	DET	@	PHA	W 15-1	44	20	5	1	0	12	7	0	4	3	0	51	27	6	0				.455	.529	.614	1.143
16	Yankees	15	9/7/1931	NYY	@	PHA	W 15-3	42	16	2	0	0	11	11	0	3	1	1	53	18	2	0				.381	.509	.429	.938
17	Senators	15	9/7/1931	WSH	@	BSA	W 15-1	42	14	5	0	0	12	6	1	0	0	0	49	19	5	0				.333	.429	.452	.881
18	Cardinals	15	9/7/1924	SLN	vs	CHC	W 15-4	37	14	4	1	0	12	6	2	1	2	1	47	20	5	2				.378	.489	.541	1.029
19	Blues	15	9/7/1878	IND	vs	MIL	W 15-6
20	Rays	14	9/7/2018	TBR	vs	BAL	W 14-2	32	10	1	0	4	13	11	0	6	1	1	44	23	5	0	1	0	0	.313	.477	.719	1.196
21	Angels	14	9/7/2014	LAA	@	MIN	W 14-4	46	19	4	1	3	13	4	1	8	0	0	52	34	8	0	1	0	0	.413	.462	.739	1.201
22	Rays	14	9/7/2010	TBR	@	BOS	W 14-5	39	12	4	0	5	13	7	0	5	1	0	47	31	9	1	0	0	0	.308	.413	.795	1.208
23	Phillies	14	9/7/2006	PHI	@	FLA	W 14-8	44	17	2	3	4	14	8	0	4	2	0	52	37	9	0	0	1	0	.386	.481	.841	1.322
24	Brewers	14	9/7/2005	MIL	@	CIN	W 14-5	42	17	4	0	5	14	8	1	8	0	0	51	36	9	0	0	0	0	.405	.510	.857	1.367
25	Angels	14	9/7/1999	ANA	vs	CWS	W 14-1	36	12	4	0	1	14	6	1	2	2	1	44	19	5	0	1	1	0	.333	.432	.528	.960