Joey Gallo had the most strikeouts in 2021, with 213 strikeouts.

Interpreted as:

most ks by a player MLB 2021

	NAME	SO	SEASON	TM	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	wRC	WRAA	wOBA	wRC+	BRAA
1	Joey Gallo J. Gallo	213	2021	TOT	153	498	90	99	13	1	38	77	111	6	6	0	616	228	52	0	1	5	6	.199	.351	.458	.808	92	17.4	.348	121	16.2
2	Matt Chapman M. Chapman	202	2021	OAK	151	529	75	111	15	3	27	72	80	4	3	2	622	213	45	0	9	0	6	.210	.314	.403	.716	74	-1.5	.311	102	1.4
3	Adolis García A. García	194	2021	TEX	149	581	77	141	26	2	31	90	32	5	16	5	622	264	59	0	4	0	15	.243	.286	.454	.741	75	-0.1	.314	97	-2.5
4	Shohei Ohtani S. Ohtani	189	2021	LAA	155	537	103	138	26	8	46	100	96	4	26	10	639	318	80	0	2	20	7	.257	.372	.592	.965	119	41.8	.393	150	39.4
5	Javier Báez J. Báez	184	2021	TOT	138	502	80	133	18	2	31	87	28	13	18	5	546	248	51	0	3	2	12	.265	.319	.494	.813	79	13.4	.344	117	11.5
6	Miguel Sanó M. Sanó	183	2021	MIN	135	470	68	105	24	0	30	75	59	2	2	1	532	219	54	0	1	2	13	.223	.312	.466	.778	72	7.5	.332	111	7.4
7	Adam Duvall A. Duvall	174	2021	TOT	146	513	67	117	17	2	38	113	35	4	5	0	555	252	57	0	3	1	7	.228	.281	.491	.772	72	4.5	.324	101	0.8
8	Eugenio Suárez E. Suárez	171	2021	CIN	145	505	71	100	23	0	31	79	56	8	0	1	574	216	54	0	5	0	14	.198	.286	.428	.713	66	-3.9	.306	85	-11
9	Salvador Perez S. Perez	170	2021	KCR	161	620	88	169	24	0	48	121	28	13	1	0	665	337	72	0	4	4	14	.273	.316	.544	.859	105	24.6	.359	125	20.4
10	Randy Arozarena R. Arozarena	170	2021	TBR	141	529	94	145	32	3	20	69	56	14	20	10	604	243	55	0	5	4	9	.274	.356	.459	.815	91	17.6	.350	128	20.4
11	Mitch Haniger M. Haniger	169	2021	SEA	157	620	110	157	23	2	39	100	54	9	1	0	691	301	64	0	8	2	12	.253	.318	.485	.804	98	14.5	.340	120	16.9
12	Tyler O'Neill T. O'Neill	168	2021	STL	138	482	89	138	26	2	34	80	38	13	15	4	537	270	62	0	4	0	8	.286	.352	.560	.912	96	30.8	.384	143	29.4
13	Austin Riley A. Riley	168	2021	ATL	160	590	91	179	33	1	33	107	52	12	0	1	662	313	67	0	8	2	11	.303	.367	.531	.898	116	35.6	.379	136	30.7
14	Dansby Swanson D. Swanson	167	2021	ATL	160	588	78	146	33	2	27	88	52	5	9	3	653	264	62	1	7	4	7	.248	.311	.449	.760	83	4.3	.322	99	-0.5
15	Chris Taylor C. Taylor	167	2021	LAD	148	507	92	129	25	4	20	73	63	8	13	1	582	222	49	1	3	2	5	.254	.344	.438	.782	82	11.4	.338	113	9.9
16	Brandon Lowe B. Lowe	167	2021	TBR	149	535	97	132	31	0	39	99	68	9	7	1	615	280	70	0	3	4	2	.247	.340	.523	.863	99	24.9	.363	137	27.8
17	Nathaniel Lowe N. Lowe	162	2021	TEX	157	557	75	147	24	3	18	72	80	2	8	0	642	231	45	0	3	2	13	.264	.357	.415	.771	90	12	.337	112	9.6
18	Kyle Seager K. Seager	161	2021	SEA	159	603	73	128	29	1	35	101	59	4	3	1	670	264	65	0	4	2	7	.212	.285	.438	.723	77	-3.8	.308	98	-1.4
19	Ryan Mountcastle R. Mountcastle	161	2021	BAL	144	534	77	136	23	1	33	89	41	4	4	3	586	260	57	0	7	2	12	.255	.309	.487	.796	81	10	.335	111	7.8
20	Aaron Judge A. Judge	158	2021	NYY	148	550	89	158	24	0	39	98	75	3	6	1	633	299	63	0	5	2	16	.287	.373	.544	.916	115	38	.387	150	38.7
21	Giancarlo Stanton G. Stanton	157	2021	NYY	139	510	64	139	19	0	35	97	63	3	0	0	579	263	54	0	3	1	22	.273	.354	.516	.870	97	26.4	.370	138	27
22	Yoán Moncada Y. Moncada	157	2021	CWS	144	520	74	137	33	1	14	61	84	10	3	2	616	214	48	0	2	1	6	.263	.375	.412	.787	91	16.7	.347	120	15.1
23	Willy Adames W. Adames	156	2021	TOT	140	497	77	130	32	1	25	73	57	0	5	4	555	239	58	0	1	1	9	.262	.337	.481	.818	83	16	.349	120	14.1
24	Ian Happ I. Happ	156	2021	CHC	148	465	63	105	20	1	25	66	62	5	9	2	535	202	46	2	1	0	12	.226	.323	.434	.757	71	6.1	.328	105	3.4
25	Bobby Dalbec B. Dalbec	156	2021	BOS	133	417	50	100	21	5	25	78	28	7	2	0	453	206	51	0	1	1	3	.240	.298	.494	.792	62	7.3	.334	106	3.3