The Cincinnati Reds had their most strikeouts in a game versus the Dodgers on August 8, 1972, with 22 strikeouts.

Interpreted as:

reds most strikeouts in a regular-season game

	TEAM	SO	DATE	TM		OPP	RESULT	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Reds	22	8/8/1972	CIN	vs	LAD	W 2-1	60	2	8	1	0	0	2	9	1	2	2	71	9	1	1	0	3	1	.133	.257	.150	.407
2	Reds	21	5/8/2001	CIN	@	ARI	L 3-4	33	3	3	0	0	0	3	5	0	2	1	41	3	0	2	1	0	0	.091	.205	.091	.296
3	Reds	20	8/30/2009	CIN	vs	LAD	L 2-3	42	2	8	0	0	1	2	4	0	1	1	46	11	1	0	0	0	0	.190	.261	.262	.523
4	Reds	19	6/13/2013	CIN	@	CHC	L 5-6	55	5	13	1	0	0	5	5	0	1	0	60	14	1	0	0	0	0	.236	.300	.255	.555
5	Reds	19	9/30/2004	CIN	@	CHC	W 2-1	41	2	6	1	1	1	2	2	0	2	0	44	12	3	1	0	0	0	.146	.186	.293	.479
6	Reds	19	9/27/1960	CIN	@	PIT	L 3-4	56	3	11	1	0	0	2	5	0	1	2	61	12	1	0	0	0	1	.196	.262	.214	.477
7	Reds	18	7/26/2023	CIN	@	MIL	L 0-3	32	0	6	2	0	0	0	0	0	0	1	32	8	2	0	0	0	1	.188	.188	.250	.438
8	Reds	18	7/14/2023	CIN	vs	MIL	L 0-1	29	0	2	0	0	0	0	2	1	0	0	32	2	0	0	0	0	0	.069	.156	.069	.225
9	Reds	18	7/28/2014	CIN	vs	ARI	L 1-2	46	1	6	1	0	1	1	5	1	0	0	55	10	2	3	0	1	0	.130	.231	.217	.448
10	Reds	18	5/28/2001	CIN	vs	CHC	L 6-9	49	6	10	3	0	0	4	2	1	2	0	52	13	3	0	0	0	1	.204	.250	.265	.515
11	Reds	18	8/26/1998	CIN	vs	CHC	L 2-9	31	2	4	1	0	1	1	4	0	0	0	35	8	2	0	0	0	0	.129	.229	.258	.487
12	Reds	18	7/28/1989	CIN	@	ATL	W 4-2	64	4	15	2	0	0	4	3	0	0	1	68	17	2	1	0	1	2	.234	.269	.266	.534
13	Reds	18	9/21/1979	CIN	@	HOU	L 2-3	47	2	8	1	0	1	2	1	0	0	0	48	12	2	0	0	1	0	.170	.188	.255	.443
14	Reds	18	7/14/1968	CIN	vs	HOU	L 1-6	31	1	5	2	0	0	0	2	0	2	0	33	7	2	0	0	0	0	.161	.212	.226	.438
15	Reds	17	5/6/2025	CIN	@	ATL	L 1-2	37	1	7	1	0	0	1	3	1	4	0	41	8	1	0	0	0	0	.189	.268	.216	.485
16	Reds	17	4/1/2024	CIN	@	PHI	W 6-3	37	6	8	1	1	1	6	5	0	5	0	42	14	3	0	0	0	0	.216	.310	.378	.688
17	Reds	17	4/12/2015	CIN	vs	STL	L 5-7	43	5	11	1	0	2	5	8	1	0	0	53	18	3	1	0	0	0	.256	.385	.419	.803
18	Reds	17	10/1/2010	CIN	vs	MIL	L 3-4	36	3	7	1	1	0	3	3	0	2	0	42	10	2	1	2	1	0	.194	.244	.278	.522
19	Reds	17	6/30/1999	CIN	vs	ARI	W 2-0	30	2	7	0	0	1	2	0	0	2	0	30	10	1	0	0	0	0	.233	.233	.333	.567
20	Reds	17	8/24/1997	CIN	@	ATL	W 6-4	40	6	10	2	0	1	6	1	0	1	1	41	15	3	0	0	0	1	.250	.268	.375	.643
21	Reds	17	6/15/1987	CIN	@	HOU	L 0-4	36	0	7	1	0	0	0	0	1	1	0	37	8	1	0	0	0	0	.194	.216	.222	.438
22	Reds	17	9/30/1964	CIN	vs	PIT	L 0-1	56	0	9	0	0	0	0	9	0	4	0	66	9	0	1	0	4	0	.161	.277	.161	.438
23	Reds	17	5/30/1962	CIN	@	MIL	W 4-3	54	4	11	1	0	1	4	8	1	1	2	65	15	2	2	0	2	0	.204	.317	.278	.595
24	Reds	16	4/9/2025	CIN	@	SFG	L 6-8	37	6	6	2	0	0	6	4	0	0	0	41	8	2	0	0	0	0	.162	.244	.216	.460
25	Reds	16	5/23/2024	CIN	vs	SDP	L 4-6	35	4	8	1	1	1	4	5	1	2	2	41	14	3	0	0	0	1	.229	.341	.400	.741