Argenx NV ADR (ARGX) had the highest return on November 30, 2017 by a US stock with a market cap of $10B+, returning 12.9%.

ASSET	DATE	% RETURN
argenx NV ADR (ARGX)	11/30/2017	12.91%
Madrigal Pharmaceuticals (MDGL)	11/30/2017	8.05%
Mr Cooper (COOP)	11/30/2017	6.33%
Insmed (INSM)	11/30/2017	5.62%
Plains All American Pipeline (PAA)	11/30/2017	5.12%
Pure Storage (PSTG)	11/30/2017	4.52%
MPLX (MPLX)	11/30/2017	4.24%
Sociedad Quimica y Minera de Chile SA ADR B (SQM)	11/30/2017	4.2%
Neurocrine Biosciences (NBIX)	11/30/2017	4.16%
Celsius (CELH)	11/30/2017	4.09%
Alnylam Pharmaceuticals (ALNY)	11/30/2017	3.96%
CVS Health (CVS)	11/30/2017	3.95%
Humana (HUM)	11/30/2017	3.88%
Ionis Pharmaceuticals (IONS)	11/30/2017	3.62%
Viper Energy Ut (VNOM)	11/30/2017	3.6%
Elevance Health (ELV)	11/30/2017	3.31%
Ascendis Pharma A-S (ASND)	11/30/2017	3.29%
Exelixis (EXEL)	11/30/2017	3.16%
Ingersoll Rand (IR)	11/30/2017	3.09%
Wayfair (W)	11/30/2017	3.08%
Devon Energy (DVN)	11/30/2017	3.08%
F5 Networks (FFIV)	11/30/2017	3.06%
Domino's Pizza Inc Common Stock (DPZ)	11/30/2017	3.04%
Targa Resources (TRGP)	11/30/2017	3.04%
Southwest Airlines (LUV)	11/30/2017	2.99%