James Harden has the most games by an active guard with 40+ points, with 107 games.

Interpreted as:

active guards most 40 or more pts regular-season games

	NAME	GP	PTS	MPG	PPG	RPG	APG	SPG	BPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TPG	MIN	REB	AST	STL	BLK	TOV	PF	+/-
1	James Harden J. Harden	107	4,854	39.5	45.4	7.4	8.1	2.1	0.7	13.3	26.2	50.8	5.6	12.8	44.2	13.1	14.9	87.9	69.2	1.2	6.2	4.8	4,226	788	869	228	79	516	318	+1074
2	Stephen Curry S. Curry	74	3,352	36.4	45.3	5.3	5.6	1.4	0.3	14.9	25.4	58.5	8.5	15.2	56.1	7.0	7.6	92.9	78.8	0.7	4.7	3.4	2,693	395	416	103	23	248	150	+870
3	Damian Lillard D. Lillard	60	2,713	39.3	45.2	4.9	7.3	1.2	0.3	14.1	25.3	55.7	6.5	12.9	50.2	10.6	11.5	92.6	74.5	0.6	4.3	2.6	2,356	293	438	71	20	156	115	+423
4	Luka Dončić L. Dončić	51	2,270	38.8	44.5	9.7	9.1	1.5	0.5	15.0	26.4	57.0	4.9	10.8	45.7	9.5	12.0	79.3	70.3	0.9	8.8	3.8	1,977	495	465	79	23	195	139	+433
5	Russell Westbrook R. Westbrook	50	2,212	39.0	44.2	9.8	8.3	1.6	0.3	15.5	30.1	51.6	3.1	7.8	40.2	10.1	12.2	82.6	62.4	2.0	7.9	5.0	1,949	491	417	78	15	251	141	+74
6	Devin Booker D. Booker	37	1,711	38.0	46.2	5.3	5.9	1.2	0.5	16.4	27.5	59.8	3.9	8.5	46.3	9.4	10.7	88.4	71.9	0.8	4.5	3.5	1,405	197	219	45	18	130	107	+295
7	Kyrie Irving K. Irving	37	1,657	39.4	44.8	4.7	5.5	1.8	0.5	15.9	26.8	59.4	5.7	10.0	56.9	7.2	7.9	91.2	73.9	0.8	3.9	2.7	1,458	173	203	66	19	100	98	+292
8	Trae Young T. Young	34	1,487	38.1	43.7	4.2	9.1	1.1	0.1	13.7	25.6	53.6	5.2	11.0	47.1	11.1	12.6	88.1	70.2	0.8	3.4	4.8	1,294	142	310	39	5	164	57	+156
9	Donovan Mitchell D. Mitchell	32	1,397	38.9	43.7	5.5	4.9	1.4	0.3	15.1	27.9	54.0	5.3	11.8	44.9	8.3	9.4	87.7	68.2	1.1	4.5	3.2	1,246	177	157	46	11	101	75	+289
10	Bradley Beal B. Beal	31	1,378	40.8	44.5	4.8	5.5	1.2	0.4	15.8	28.0	56.5	4.6	9.4	48.6	8.3	9.6	86.2	69.0	1.4	3.4	3.1	1,265	148	169	36	12	96	80	+29
11	Shai Gilgeous-Alexander S. Gilgeous-Alexander	28	1,226	36.9	43.8	5.6	5.9	1.9	1.1	14.6	24.8	58.9	2.4	5.1	46.2	12.2	13.5	90.5	71.3	0.9	4.8	2.3	1,032	157	164	54	32	64	72	+377
12	DeMar DeRozan D. DeRozan	26	1,116	40.3	42.9	6.1	4.5	1.2	0.4	15.3	26.6	57.4	1.5	3.5	41.3	10.9	12.7	85.8	66.6	1.1	5.0	2.3	1,047	159	116	32	10	61	58	+211
13	Anthony Edwards A. Edwards	24	1,054	38.7	43.9	6.0	3.9	1.6	0.8	14.8	26.9	55.1	5.8	12.2	47.8	8.4	10.3	82.1	69.9	1.0	5.0	3.5	928	144	94	39	20	83	49	+227
14	Zach LaVine Z. LaVine	24	1,038	39.0	43.3	5.3	3.5	1.4	0.3	15.6	25.9	60.4	6.7	11.6	57.9	5.3	6.3	83.6	75.4	0.8	4.5	3.5	936	127	83	33	7	83	56	+140
15	Jalen Brunson J. Brunson	19	848	38.6	44.6	4.8	6.5	1.1	0.2	15.8	28.3	55.9	4.0	8.5	46.9	8.9	10.5	85.0	67.7	1.2	3.7	2.6	733	92	123	20	4	49	33	+155
16	Klay Thompson K. Thompson	18	803	33.5	44.6	3.8	1.8	0.9	0.7	15.6	24.9	62.6	8.8	14.3	61.2	4.6	5.0	92.2	82.2	0.4	3.4	1.9	603	69	33	16	12	34	23	+421
17	De'Aaron Fox D. Fox	16	698	39.4	43.6	4.6	6.8	2.3	0.3	16.0	28.0	57.1	4.3	9.3	46.3	7.3	9.7	75.5	67.6	0.7	3.9	3.3	630	73	108	36	5	52	50	+7
18	CJ McCollum	16	689	38.0	43.1	5.3	5.0	1.2	0.4	15.9	26.3	60.7	6.3	11.3	55.2	4.9	6.1	81.4	74.5	0.8	4.6	2.4	608	85	80	19	7	38	36	+178
19	Tyrese Maxey T. Maxey	13	590	43.1	45.4	4.5	5.6	1.4	0.9	15.4	28.8	53.3	5.2	11.5	44.7	9.5	10.8	87.2	67.5	0.4	4.1	2.6	560	58	73	18	12	34	35	+128
20	Cam Thomas C. Thomas	10	431	37.1	43.1	3.3	3.1	0.6	0.3	14.6	26.0	56.2	5.2	10.4	50.0	8.7	9.5	91.6	71.4	0.5	2.8	3.5	371	33	31	6	3	35	25	-8
21	Jalen Green J. Green	9	371	37.8	41.2	4.4	3.3	0.9	0.3	13.6	22.2	61.0	5.2	9.7	54.0	8.9	10.2	87.0	77.1	0.8	3.7	2.6	340	40	30	8	3	23	14	+86
22	Ja Morant J. Morant	9	401	35.6	44.6	5.3	6.7	1.3	0.7	15.7	25.4	61.6	3.2	5.0	64.4	10.0	12.3	81.1	72.2	1.2	4.1	3.3	321	48	60	12	6	30	19	+84
23	Jamal Murray J. Murray	8	380	38.1	47.5	5.0	4.9	1.0	0.1	18.0	27.4	65.8	7.0	11.0	63.6	4.5	5.0	90.0	80.3	0.5	4.5	2.8	305	40	39	8	1	22	12	+144
24	Chris Paul C. Paul	8	333	41.5	41.6	5.4	11.0	4.3	0.0	14.8	24.9	59.3	4.0	7.9	50.8	8.1	8.8	92.9	72.5	1.1	4.3	2.5	332	43	88	34	0	20	20	+60
25	Cade Cunningham C. Cunningham	6	252	39.3	42.0	7.7	6.8	2.0	0.8	14.8	29.2	50.9	3.2	7.5	42.2	9.2	10.5	87.3	62.2	2.0	5.7	3.0	236	46	41	12	5	18	15	+48